Portage Microbiology Exam #6 Questions With Complete
Solutions
A drug company is trying to develop a new drug that will inhibit
the release of newly produced viral particles. Would the drug
company target hemagglutin proteins or nauraminidase proteins?
Why? Correct Answers Neuraminidase because it involves the
budding and release of viral particles from the host cell
A patient diagnosed with German measles may additionally
experience what disease? Select all that apply
A. Impetigo
B. Conjuctivitis
C. Rheumatic fever
D. Influenza-like symptoms Correct Answers B and D
A person who has neither previously had chickenpox nor been
administered the VZV vaccine is exposed to someone with an
active VZV (shingles) outbreak and becomes infected. Explain
why (or why not) the person will only develop shingles Correct
Answers The infected individual will not develop shingles, but
will develop chicken pox. Unvaccinated and unexposed
individuals must first develop chickenpox, as shingles is the
reactivation of the dormant VZV virus from the chickenpox
infection
A virus that infects bacteria is called a _____ and contains a
_____ -side polygon capsid (fill in the blank) Correct Answers
Bacteriophage; 20-sided
, As individual infected with HIV is placed on anti-retroviral
medication. Describe how the medication will affect the virus.
Correct Answers Anti-retrovirals are intended to inhibit the
process of reverse-transcription. Once the virus enters the cell
and uncoating is complete, the viral enzyme reverse
transcriptase acts on the two RNA copies, creating a
complementary DNA strand. Anti-retrovirals attempt to block
this step. In the absence of anti-retroviral medications, the now
double-stranded DNA is transported to the nucleus where it can
integrate into the host genome and begin replicating. By
inhibiting the process of RT, anti-retroviral medications
effectively block the production of new viruses by preventing its
integration and replication.
Based on the following image, would you expect the viral titer
to be high or low? Why? (cloudy) Correct Answers Low. As
turbidity is a function of the number of intact bacterial cells
present in the media, the amount of virus contained within the
above tube must be low. As the lytic continues more and more
bacterial cells will be destroyed, effectively clearing the media.
By whom and where was the first Polio vaccine developed?
Correct Answers Jonas Salk and his research team developed
the polio vaccine at the University of Pittsburgh in 1955
Describe the main differences between lytic and temperate
phages (short answer) Correct Answers Lytic bacteriophages
replicate within the host bacteria until it ruptures, whereas
temperate phages primarily exist in a non-replicative state that
does not kill the host cell
Solutions
A drug company is trying to develop a new drug that will inhibit
the release of newly produced viral particles. Would the drug
company target hemagglutin proteins or nauraminidase proteins?
Why? Correct Answers Neuraminidase because it involves the
budding and release of viral particles from the host cell
A patient diagnosed with German measles may additionally
experience what disease? Select all that apply
A. Impetigo
B. Conjuctivitis
C. Rheumatic fever
D. Influenza-like symptoms Correct Answers B and D
A person who has neither previously had chickenpox nor been
administered the VZV vaccine is exposed to someone with an
active VZV (shingles) outbreak and becomes infected. Explain
why (or why not) the person will only develop shingles Correct
Answers The infected individual will not develop shingles, but
will develop chicken pox. Unvaccinated and unexposed
individuals must first develop chickenpox, as shingles is the
reactivation of the dormant VZV virus from the chickenpox
infection
A virus that infects bacteria is called a _____ and contains a
_____ -side polygon capsid (fill in the blank) Correct Answers
Bacteriophage; 20-sided
, As individual infected with HIV is placed on anti-retroviral
medication. Describe how the medication will affect the virus.
Correct Answers Anti-retrovirals are intended to inhibit the
process of reverse-transcription. Once the virus enters the cell
and uncoating is complete, the viral enzyme reverse
transcriptase acts on the two RNA copies, creating a
complementary DNA strand. Anti-retrovirals attempt to block
this step. In the absence of anti-retroviral medications, the now
double-stranded DNA is transported to the nucleus where it can
integrate into the host genome and begin replicating. By
inhibiting the process of RT, anti-retroviral medications
effectively block the production of new viruses by preventing its
integration and replication.
Based on the following image, would you expect the viral titer
to be high or low? Why? (cloudy) Correct Answers Low. As
turbidity is a function of the number of intact bacterial cells
present in the media, the amount of virus contained within the
above tube must be low. As the lytic continues more and more
bacterial cells will be destroyed, effectively clearing the media.
By whom and where was the first Polio vaccine developed?
Correct Answers Jonas Salk and his research team developed
the polio vaccine at the University of Pittsburgh in 1955
Describe the main differences between lytic and temperate
phages (short answer) Correct Answers Lytic bacteriophages
replicate within the host bacteria until it ruptures, whereas
temperate phages primarily exist in a non-replicative state that
does not kill the host cell
