1
NUR 378
Exam 1: NUR 378 Pharmacology – Concordia
University St. Paul.
What are the effects of kidney disease on drugs excreted by the
kidneys? - ANS Kidney disease can reduce drug excretion causing drugs
to accumulate in the body.
What are the advantages and disadvantages of medications? - ANS
Advantages: medications have a therapeutic objective which is to
provide maximum benefit with minimal harm.
Disadvantages: unwanted side effects, drug-drug/food interactions,
narrow therapeutic index, toxicity, paradoxical effect, idiosyncratic
effect, allergic reaction, teratogenicity, and iatrogenic disease.
How can nonpharmacologic treatments affect pharmacologic
treatments? - ANS Nondrug measures can help promote therapeutic
effects and should be included in the plan of care.
NUR 378
, 2
NUR 378
How does medication compliance affect therapeutic effects of
medications? - ANS Adherence is essential to achieve therapeutic
objective of a drug.
Describe the principles of pharmacodynamics. - ANS
Pharmacodynamics is: the study of the biochemical and physiologic
effects of drugs on the body and the molecular mechanisms by which
those effects are produced.
1: Dose-response relationship
Size of an administered dose and the intensity of the response
produced.
2: Drug-receptor interactions
Because most drugs work at the receptor level to alter the physiological
function and produce its effects.
3: therapeutic index:
Lower the index = less amount of the drug needed before it is lethal.
NUR 378
, 3
NUR 378
What are the priorities of the nurse after administering new
medications to a patient? - ANS - Evaluate clients' response to
medications
- Use knowledge of therapeutic effect and common adverse effects to
compare expected outcomes with actual findings
- Identify adverse effects
- Notify provider of all errors, and implement corrective measures
immediately
How does a patient with CYP2C9 variant metabolize warfarin? - ANS
The variant causes Warfarin to be metabolized slowly and accumulate
in the body to a dangerous level. = TOXICITY
What is the nurse's responsibilities before administering any
medication? - ANS - Knowledge about the medication being
administered
- Obtaining information regarding medical diagnosis and conditions that
might affect medication administration
NUR 378
NUR 378
Exam 1: NUR 378 Pharmacology – Concordia
University St. Paul.
What are the effects of kidney disease on drugs excreted by the
kidneys? - ANS Kidney disease can reduce drug excretion causing drugs
to accumulate in the body.
What are the advantages and disadvantages of medications? - ANS
Advantages: medications have a therapeutic objective which is to
provide maximum benefit with minimal harm.
Disadvantages: unwanted side effects, drug-drug/food interactions,
narrow therapeutic index, toxicity, paradoxical effect, idiosyncratic
effect, allergic reaction, teratogenicity, and iatrogenic disease.
How can nonpharmacologic treatments affect pharmacologic
treatments? - ANS Nondrug measures can help promote therapeutic
effects and should be included in the plan of care.
NUR 378
, 2
NUR 378
How does medication compliance affect therapeutic effects of
medications? - ANS Adherence is essential to achieve therapeutic
objective of a drug.
Describe the principles of pharmacodynamics. - ANS
Pharmacodynamics is: the study of the biochemical and physiologic
effects of drugs on the body and the molecular mechanisms by which
those effects are produced.
1: Dose-response relationship
Size of an administered dose and the intensity of the response
produced.
2: Drug-receptor interactions
Because most drugs work at the receptor level to alter the physiological
function and produce its effects.
3: therapeutic index:
Lower the index = less amount of the drug needed before it is lethal.
NUR 378
, 3
NUR 378
What are the priorities of the nurse after administering new
medications to a patient? - ANS - Evaluate clients' response to
medications
- Use knowledge of therapeutic effect and common adverse effects to
compare expected outcomes with actual findings
- Identify adverse effects
- Notify provider of all errors, and implement corrective measures
immediately
How does a patient with CYP2C9 variant metabolize warfarin? - ANS
The variant causes Warfarin to be metabolized slowly and accumulate
in the body to a dangerous level. = TOXICITY
What is the nurse's responsibilities before administering any
medication? - ANS - Knowledge about the medication being
administered
- Obtaining information regarding medical diagnosis and conditions that
might affect medication administration
NUR 378
