,Genetics: An Integrated Approach (Sanders)
Chapter 1 The Molecular Basis of Heredity, Variation, and Evolution
1.1 Multiple-Choice Questions
1) Bacteria are single-celled organisms with a single chromosome found in which cell space?
A) nucleus
B) nucleolus
C) nucleoid
D) nuclear envelope
E) mitochondria
Answer: C
Section: 1.1
Skill: Knowledge/Comprehension
2) Sexual reproduction uses to generate gametes, which join at fertilization.
A) meiosis; haploid
B) mitosis; haploid
C) meiosis; diploid
D) mitosis; diploid
E) mitosis; identical
Answer: A
Section: 1.1
Skill: Knowledge/Comprehension
3) When a diploid cell divides by mitosis, the result is .
A) identical haploid cells
B) identical diploid cells
C) unique diploid cells
D) unique haploid cells
E) a zygote.
Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
4) Modern genetics consists of three major branches. Which of these branches, also known as
“transmission genetics,” involves the study of the transmission of traits and characteristics in
successive generations?
A) evolutionary
B) Mendelian
C) molecular
D) population
E) reproductive
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, Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
5) You identify a new unicellular organism with multiple chromosomes organized by proteins within
the cell’s nucleus. Into which of the three domains of life might this organism fit?
A) Archaea
B) Bacteria
C) Eukarya
D) Archaea or Bacteria
E) Archaea or Eukarya
Answer: C
Section: 1.1
Skill: Application/Analysis
6) Watson and Crick used evidence from several studies to determine the structure of DNA. What
conclusion were they able to draw from Rosalind Franklin’s X-ray diffraction data, specifically?
A) DNA consists of four types of nucleotide bases: A, T, C, and G.
B) DNA nucleotides form complementary base pairs.
C) Adenine pairs with thymine and cytosine pairs with guanine when they are on opposite DNA
strands.
D) DNA is a duplex, with two strands forming a double helix.
E) The DNA strands are antiparallel, and the strands are held together by hydrogen bonds.
Answer: D
Section: 1.2
Skill: Knowledge/Comprehension
7) What kind of bond is formed between the 5′ phosphate group of one nucleotide and the 3′ hydroxyl
(OH) group of the adjacent nucleotide?
A) ionic bond
B) phosphodiester bond
C) hydrogen bond
D) disulfide bond
E) hydroxyl bond
Answer: B
Section: 1.2
Skill: Knowledge/Comprehension
8) What kind of bond is formed between complementary base pairs to join the two DNA strands into a
double helix?
A) ionic bond
B) phosphodiester bond
C) hydrogen bond
D) disulfide bond
E) peptide bond
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, Answer: C
Section: 1.2
Skill: Knowledge/Comprehension
9) Which type(s) of RNA is/are translated into proteins?
A) mRNA
B) rRNA
C) tRNA
D) mRNA and rRNA
E) mRNA, rRNA, and tRNA
Answer: A
Section: 1.3
Skill: Knowledge/Comprehension
10) Which enzyme is active in DNA replication?
A) DNA polymerase
B) RNA polymerase
C) reverse transcriptase
D) aminoacyl-tRNA synthetase
E) RNase
Answer: A
Section: 1.2
Skill: Knowledge/Comprehension
11) The promoter is bound by which enzyme?
A) DNA polymerase
B) RNA polymerase
C) Reverse transcriptase
D) DNase
E) RNase
Answer: B
Section: 1.3
Skill: Knowledge/Comprehension
12) What is the process of synthesizing proteins from mRNA sequences?
A) replication
B) transcription
C) translation
D) transformation
E) transduction
Answer: C
Section: 1.3
Skill: Knowledge/Comprehension
3
Copyright © 2016 Pearson Education, Inc.
Chapter 1 The Molecular Basis of Heredity, Variation, and Evolution
1.1 Multiple-Choice Questions
1) Bacteria are single-celled organisms with a single chromosome found in which cell space?
A) nucleus
B) nucleolus
C) nucleoid
D) nuclear envelope
E) mitochondria
Answer: C
Section: 1.1
Skill: Knowledge/Comprehension
2) Sexual reproduction uses to generate gametes, which join at fertilization.
A) meiosis; haploid
B) mitosis; haploid
C) meiosis; diploid
D) mitosis; diploid
E) mitosis; identical
Answer: A
Section: 1.1
Skill: Knowledge/Comprehension
3) When a diploid cell divides by mitosis, the result is .
A) identical haploid cells
B) identical diploid cells
C) unique diploid cells
D) unique haploid cells
E) a zygote.
Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
4) Modern genetics consists of three major branches. Which of these branches, also known as
“transmission genetics,” involves the study of the transmission of traits and characteristics in
successive generations?
A) evolutionary
B) Mendelian
C) molecular
D) population
E) reproductive
1
Copyright © 2016 Pearson Education, Inc.
, Answer: B
Section: 1.1
Skill: Knowledge/Comprehension
5) You identify a new unicellular organism with multiple chromosomes organized by proteins within
the cell’s nucleus. Into which of the three domains of life might this organism fit?
A) Archaea
B) Bacteria
C) Eukarya
D) Archaea or Bacteria
E) Archaea or Eukarya
Answer: C
Section: 1.1
Skill: Application/Analysis
6) Watson and Crick used evidence from several studies to determine the structure of DNA. What
conclusion were they able to draw from Rosalind Franklin’s X-ray diffraction data, specifically?
A) DNA consists of four types of nucleotide bases: A, T, C, and G.
B) DNA nucleotides form complementary base pairs.
C) Adenine pairs with thymine and cytosine pairs with guanine when they are on opposite DNA
strands.
D) DNA is a duplex, with two strands forming a double helix.
E) The DNA strands are antiparallel, and the strands are held together by hydrogen bonds.
Answer: D
Section: 1.2
Skill: Knowledge/Comprehension
7) What kind of bond is formed between the 5′ phosphate group of one nucleotide and the 3′ hydroxyl
(OH) group of the adjacent nucleotide?
A) ionic bond
B) phosphodiester bond
C) hydrogen bond
D) disulfide bond
E) hydroxyl bond
Answer: B
Section: 1.2
Skill: Knowledge/Comprehension
8) What kind of bond is formed between complementary base pairs to join the two DNA strands into a
double helix?
A) ionic bond
B) phosphodiester bond
C) hydrogen bond
D) disulfide bond
E) peptide bond
2
Copyright © 2016 Pearson Education, Inc.
, Answer: C
Section: 1.2
Skill: Knowledge/Comprehension
9) Which type(s) of RNA is/are translated into proteins?
A) mRNA
B) rRNA
C) tRNA
D) mRNA and rRNA
E) mRNA, rRNA, and tRNA
Answer: A
Section: 1.3
Skill: Knowledge/Comprehension
10) Which enzyme is active in DNA replication?
A) DNA polymerase
B) RNA polymerase
C) reverse transcriptase
D) aminoacyl-tRNA synthetase
E) RNase
Answer: A
Section: 1.2
Skill: Knowledge/Comprehension
11) The promoter is bound by which enzyme?
A) DNA polymerase
B) RNA polymerase
C) Reverse transcriptase
D) DNase
E) RNase
Answer: B
Section: 1.3
Skill: Knowledge/Comprehension
12) What is the process of synthesizing proteins from mRNA sequences?
A) replication
B) transcription
C) translation
D) transformation
E) transduction
Answer: C
Section: 1.3
Skill: Knowledge/Comprehension
3
Copyright © 2016 Pearson Education, Inc.
