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Examen

HOSA PHARMACOLOGY LATEST EXAM ACTUAL EXAM 2025

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HOSA PHARMACOLOGY LATEST EXAM ACTUAL EXAM 2025 Which method of medication administration provides the client with the greatest first pass effect? A) Oral. B) Sublingual. C) Intravenous. D) Subcutaneous - Correct Answer-A) Oral An older client with a decreased percentage of lean body mass is likely to receive a prescription that is adjusted based on which pharmacokinetic process? A) Absorption B) Metabolism C) Elimination D) Distribution - Correct Answer-D) Distribution Which of the following is a parenteral method of administering a drug? A) Topical B) Oral C) Sublingual D) Rectal - Correct Answer-A) Topical Which of the following is an enteral method of administering drugs? A. Rectal B. Intranasal C. Topical D. Tracheal - Correct Answer-A. Rectal How are the solid forms of drugs most frequently administered? A. Parenteral B. Intravenous C. Enteral D. Inhalation - Correct Answer-C. Enteral Which of the following methods of medication administration is described as readily available, painless, and noninvasive but has limited value in an emergent situation because of slow or erratic absorption? A. Sublingual B. Oral C. Topical D. Rectal - Correct Answer-B. Oral HOSA HOSA What method of medication administration is best described as painless and has a rapid onset of action but requires a responsive, cooperative patient with an intact gag reflex? A. Topical B. Oral C. IV D. Buccal - Correct Answer-D. Buccal Which of the following methods of medication administration is easily accessible during an active seizure if an IV is unobtainable? A. IO B. SL C. Rectal D. Tracheal - Correct Answer-C. Rectal Which of the following medication administration methods has an immediate onset and is easily accessible, but is painful and time-consuming and has a significant potential for causing adverse reactions? A. IM B. SL C. Rectal D. IV - Correct Answer-D. IV Valium is an example of which type of drug name? A. Generic name B. Chemical name C. Official name D. Trade name - Correct Answer-D. Trade name Which of the following best describes the absorption of topical nitroglycerin in a patient with poor peripheral circulation? A. Absorption is enhanced, and the results may be stronger than expected. B. Absorption decreases, and the results may be stronger than expected. C. Absorption is unchanged, and the results can be typical. D. Absorption decreases, and the results may be less than desired. - Correct Answer-D. Absorption decreases, and the results may be less than desired. Which of the following terms is best defined as the passive transport of solutes? A. Absorption B. Diffusion C. Osmosis D. Concentration - Correct Answer-B. Diffusion The method of administration of a drug will have the greatest impact on which of the following actions? HOSA HOSA A. Absorption B. Excretion C. Metabolism D. Elimination - Correct Answer-A. Absorption Which of the following terms is used to describe a drug that produces a physiologic response when bonded with a receptor? A. Affinity B. Partial agonist C. Antagonist D. Agonist - Correct Answer-D. Agonist Which of the following terms describes the amount of a drug that is required to provide a beneficial effect in 50% of the drug-tested population? A. Therapeutic dose B. Plasma-level profile C. Therapy state D. Lethal dose - Correct Answer-A. Therapeutic dose Which of the following routes of administration provides the fastest rate of absorption? A. IM B. PO C. IV D. Sub-Q - Correct Answer-C. IV Which of the following actions is most likely to occur when a patient with chronic renal failure receives a medication? A. Liver failure along with renal failure B. Impaired ability to eliminate the drug C. Kidney stones from an excess of drug in the system D. A need for a diuretic to help eliminate the drug - Correct Answer-B. Impaired ability to eliminate the drug Which of the following drug classifications is an example of a drug's mechanism of action? A. Chemical classification B. Cardiac therapy C. Therapeutic classification D. Physiologic classification - Correct Answer-C. Therapeutic classification Which of the following drug classifications would best describe the bronchodilation effects of Brethine? A. Class of agent B. Mechanism of action C. Body system HOSA HOSA D. Physiologic classification - Correct Answer-B. Mechanism of action Once a drug has been developed, what is the next step the pharmaceutical company must take to gain FDA approval? A. Put the drug into the U.S. Pharmacopoia before allowing any sales. B. Secure a patent on the medication, and then sell it to various pharmacies. C. List the medication on the stock market to recoup development costs. D. Test the drug's effectiveness as an investigational drug. - Correct Answer-D. Test the drug's effectiveness as an investigational drug. Which of the following best describes why standardization of drugs is necessary? A. Drugs are produced by the same company under different names. B. Drugs have different doses depending on whether they are brand-name or generic drugs. C. Drugs do not vary by dose and length of action based on where the drug is made. D. Drugs may vary by strength and activity among drug manufacturers. - Correct Answer-D. Drugs may vary by strength and activity among drug manufacturers. Why is it important to know and understand the medications a patient is taking? A. For testing purposes B. For safe medication administration C. For documentation purposes D. For billing purposes - Correct Answer-B. For safe medication administration With ________ classifications, drugs are organized on the basis of their usefulness in treating a particular disorder. A. therapeutic B. pharmacologic c. chemical - Correct Answer-A. therapeutic Drugs organized by ______ classifications are categorized based on how they produce their effects in the body. A. therapeutic B. pharmacologic c. chemical - Correct Answer-B. pharmacologic A ________ drug is the original, well-understood drug model from which other drugs in a particular class have been deployed. - Correct Answer-Prototype The description given to a drug by the International Union of Pure and Applied Chemistry (IUPAC) is its __________ name. - Correct Answer-Chemical The three types of drug names are: - Correct Answer-chemical, generic, and trade names HOSA HOSA One of the main arguments against substituting generic drugs for brand name drugs is differences in: - Correct Answer-Bioavailability Drugs with more than one active ingredient are called: - Correct Answer-Combination drugs The process of drug movement to achieve drug action - Correct Answer Pharmacokinetics What is the key to the therapeutic classification of a drug? - Correct Answer-Link the disorder to the drug's clinical usefulness A drug's trade name is assigned by whom? - Correct Answer-developing pharmaceutical company Why is a drug scheduled drug? - Correct Answer-the drug can cause dependency What is an example of a commonly scheduled drug? - Correct Answer-Morphine In the United States, what law or agency restricts the use of controlled substances? - Correct Answer-Controlled Substances Act If for a particular drug there are no controlled studies in women or if studies in women and animals are not available to establish risk in pregnancy, the FDA classification is: - Correct Answer-Category C The _______ route means the nurse will administer the drug to the patient by mounts, under the tongue, or into the rectum. - Correct Answer

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HOSA




HOSA PHARMACOLOGY MIDTERM
EXAM 2025
Absorption - -Process by which a drug enters the circulatory system (blood).

Intravenous (IV) & Intra-Arterial - -Administration/Dosage routs that do not require
absorption.

Absorption, Distribution, Metabolism, & Elimination... The Pharmacokinetic Process - -
ADME

Addiction - -Dependence characterized by a perceived need to take a drug to attain the
psychological & physical effects of mood altering substances.

Affinity - -Natural attraction - the strength by which a particular chemical messenger
binds to its receptor site on a cell

Agonist - -Drug that mimics the action of a neurotransmitter when it binds to a particular
receptor site - i.e. & triggers the cell's response in a manner similar to the action of the
body's own chemical messenger.

Allergen - -Substance of a usually harmless nature that produces an abnormal
hypersensitive reaction.

Allergic Response - -A hypersensitive reaction to any usually harmless substance that
does not normally cause a reaction.

Anaphylactic Reaction - -Severe allergic response resulting in immediate life-
threatening respiratory distress, usually followed by vascular collapse & shock
accompanied w/ hives.

Angioedema - -Abnormal accumulation of fluid in tissue.

Antagonist - -Drug that neutralizes or counteracts the effects of a neurotransmitter or
another drug when it binds to a particular receptor site.

Antigen - -Foreign substance that is recognized by the immune system & induces the
immune system to produce antibodies to defend against the foreign substance.

Bioavailability - -Degree to which a drug or other substance becomes available to the
target tissue after administration.




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Blood-Brain Barrier - -Fortified area that prevents many substances from entering the
cerebro-spinal fluid from the blood. This area is formed by glial cells that envelope
capillaries in the fcentral nervous system. This creates a shield that blocks many water-
soluble compounds, but is permeable to lipid-soluble substances.

Ceiling Effect - -Point @ which no clinical response occurs w/ increased dosage of a
drug.

Clearance - -Rate @ which a drug is eliminated from a specific volume of blood per unit
of time.

Contraindication - -Any disease, condition, or symptom for which a drug will not be
beneficial & may be harmful.

Dependence - -State in which a person's body has adapted physiologically &
psychologically to a drug & cannot function w/o it.

Distribution - -Process by which a drug moves from the blood into other body fluids &
tissues & ultimately to its site(s) of action.

Dose - -Quantity of a drug administered at one time.

Drug Abuse - -Use of a drug for purposes other than those prescribed &/or in amounts
that were not directed. This is often linked to addiction.

Drug Interaction - -When a drug is affected in some way by another drug, foods, or
other substances, such as when enzymes that metabolize the drug are induced or
inhibited.

Drug Interaction Relationship: Addition - -The combined effect of 2 drugs is equal to the
sum of the effects of each drug taken alone.

Drug Interaction Relationship: Antagonism - -The action of 1 drug negates the action of
a 2nd drug.

Drug Interaction Relationship: Potentiation - -1 drug increases or prolongs the action of
another drug, & the total effect is greater than the sum of the effects of each drug used
alone - drug potency is increased.

Drug Interaction Relationship: Synergism - -The combined effect of 2 drugs is more
intense or longer in duration than the sum of their individual effects. Drugs that work in
combination like this are usually prescribed together.

Enzymes, Nucleic Acids, Receptors, & Transport Proteins - -Types of specific body
molecules that drugs can combine w/.



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Duration Of Action - -Length of time a drug gives the desired response/remains at the
therapeutic level.

Elimination - -Removal of a drug or the drugs metabolites from the body by excretion.

First-Order - -Drugs for which the rate of elimination is concentration dependent (as
opposed to ____ _ _____).

First-Pass Effect - -Extent to which a drug is metabolized by the liver before reaching
full body circulation. This can substantially decrease bioavailability of certain drugs
when administered orally, in which case administration by injection is required.

Half-Life - -Time necessary for the body to eliminate half of the drug in the body @ any
1 time (written as T 1/2).

Homeostasis - -Maintenance of stability in the internal environment of the body.

Induction - -Process by which a drug increases the concentration of certain enzymes
that affect the pharmacologic response to other drugs.

Inhibition - -Process by which a drug blocks enzyme activity & impairs the metabolism of
another drug.

Interaction - -Change in the action of a drug caused by another drug, food, or another
substance, such as alcohol or nicotine.

Lipid - -Fatty molecule - An important constituent of cell membranes; they generally
repel water.

Local Effect - -Action of a drug that is confined to a specific part of the body.

Loading Dose - -Amt of a drug that will bring the blood concentration rapidly to a
therapeutic level.

Maintenance Dose - -Amt of a drug administered at regular intervals to keep the blood
concentration @ a therapeutic level. An important factor in determining this, is a drug's
clearance rate.

Metabolic Pathway - -Sequence of chemical steps that convert a drug tinto a metabolite.

Metabolism - -Process by which drugs are chemically converted to other compounds.

Metabolite - -Substance into which a drug is chemically converted in the body.




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Peak - -Top or upper limit of a drug's concentration in the blood.

Pharmacokinetic Modeling - -Method of describing the process of absorption,
distribution, metabolism, & elimination (ADME) of drug w/i the body mathematically.

Pharmacokinetics - -Activity of a drug w/i the body over a period of time; includes
absorption, distribution, metabolism, & elimination (ADME).

Prophylaxis - -Effect of a drug in preventing infection or disease.

Pruritus - -Itching Sensation.

Receptor - -Protein molecule on the surface of or w/i a cell that recognizes & binds w/
specific molecules, thereby producing some effect w/i the cell.

Side Effect - -Secondary response to a drug other than the primary therapeutic effect for
which the drug was inteneded.

Solubility - -Ability of a drug to dissolve in body fluids.

Specificity - -Property of a cell receptor that enables it to bind only w/ a specific
chemical messenger complementary to the structure of the receptor.

Systemic Effect - -Action of a drug that has generalized - the all-inclusive effect of the
drug on the body.

Therapeutic Effect - -Desired action of a drug in the treatment of a particular disease ,
state, or symptom.

Therapeutic Level - -Amount of a drug in the blood @ which beneficial effects occur.
The amt. of time required to achieve this can be shortened by administering a loading
dose.

Therapeutic Range - -Optimum Dosage, providing the best chance for achieving the
most effective & desired action... Dosing below this range has little effect, while dosing
above this level (overdosing) can lead to toxicity & death.

Tolerance - -Decrease in response to the effects of a drug as it continues to be
administered.

Trough - -Lowest level of a drug in the blood.

Urticaria - -Hives, itching sensation.




HOSA

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