REAL HESI PHARMACOLOGY EXAM QUESTIONS AND
ANSWERS LATEST UPDATE 2025/ 2026
A male client who has been taking a high dose of a nonsteroidal anti-inflammatory drug (NSAID) comes
to the clinic complaining of gastric pain and blood in his stool. The healthcare provider discontinues the
NSAIDs and prescribes esomeprazole. Which information should the client include in the nurse's
teaching plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland foods
C. Notify the healthcare provider of the passage of black stool
D. Call the clinic if diarrhea or headache occur when taking esomeprazole - CORRECT ANSWERS >> C.
Notify the healthcare provider of the passage of black stool
When administering zolpidem to an older client, which computer documentation indicates that the
desired outcome has
been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate - CORRECT ANSWERS >> A. Sleeps soundly through the night
A male client with a fungal infection of the toenail reports to the nurse that he has been applying an
over-the-counter triple antibiotic ointment to the infection daily for two weeks without any
improvement. Which action should the nurse take?
A. Instruct the client to obtain a prescription for oral terbinafine
B. Suggest that the client use the ointment twice a day to be more effective
C. Reassure that the treatment of fungus-infected toenails often takes several months
D. Advise the client to obtain a prescription-strength formulation of the ointment - CORRECT ANSWERS
>> A. Instruct the client to obtain a prescription for oral terbinafine
A client with a nasogastric tube (NGT) has a prescription for sucralfate. The liquid form of the medication
is not currently available in the pharmacy and tablets have been delivered to the medication dispensing
system. Which action should the nurse include when administering the medication?
, A. Crush the tablet and mix it with water separately from other medications
B. Crush the tablet and mix it with other crushed tablets diluted in water
C. Withhold the medication until a liquid form is available on the nursing unit
D. Crush the tablet and mix it with other liquid medications for administration - CORRECT ANSWERS >>
A. Crush the tablet and mix it with water separately from other medications
A client with chronic asthma receives a prescription for montelukast, a leukotriene modifier. Which
statement by the client indicates to the nurse that medication teaching was effective?
A. I should take this medication only when I am having an asthma attack
B. I will take the tablet every evening to control my asthma
C. This medication will stop an asthma attack immediately
D. I will not need to use my inhalers twice a day when I start this medication - CORRECT ANSWERS >> B.
I will take the tablet every evening to control my asthma
The nurse is planning to administer the antiulcer GI agent sucralfate to a client with peptic ulcer disease.
Which action should the nurse include in this client's plan of care?
A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
D. Monitor for electrolyte imbalance - CORRECT ANSWERS >> C. Give sucralfate once a day, preferably
at bedtime
A client with anemia secondary to chronic kidney disease (CKD) started a prescription for epoetin alfa
two months ago. Which client finding best indicates that the medication is effective?
A. Reports of increased energy levels and decreased fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich foods
D. Hemoglobin level increased to 12 grams/dL (120 mmol/L) - CORRECT ANSWERS >> D. Hemoglobin
level increased to 12 grams/dL (120 mmol/L)
ANSWERS LATEST UPDATE 2025/ 2026
A male client who has been taking a high dose of a nonsteroidal anti-inflammatory drug (NSAID) comes
to the clinic complaining of gastric pain and blood in his stool. The healthcare provider discontinues the
NSAIDs and prescribes esomeprazole. Which information should the client include in the nurse's
teaching plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland foods
C. Notify the healthcare provider of the passage of black stool
D. Call the clinic if diarrhea or headache occur when taking esomeprazole - CORRECT ANSWERS >> C.
Notify the healthcare provider of the passage of black stool
When administering zolpidem to an older client, which computer documentation indicates that the
desired outcome has
been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate - CORRECT ANSWERS >> A. Sleeps soundly through the night
A male client with a fungal infection of the toenail reports to the nurse that he has been applying an
over-the-counter triple antibiotic ointment to the infection daily for two weeks without any
improvement. Which action should the nurse take?
A. Instruct the client to obtain a prescription for oral terbinafine
B. Suggest that the client use the ointment twice a day to be more effective
C. Reassure that the treatment of fungus-infected toenails often takes several months
D. Advise the client to obtain a prescription-strength formulation of the ointment - CORRECT ANSWERS
>> A. Instruct the client to obtain a prescription for oral terbinafine
A client with a nasogastric tube (NGT) has a prescription for sucralfate. The liquid form of the medication
is not currently available in the pharmacy and tablets have been delivered to the medication dispensing
system. Which action should the nurse include when administering the medication?
, A. Crush the tablet and mix it with water separately from other medications
B. Crush the tablet and mix it with other crushed tablets diluted in water
C. Withhold the medication until a liquid form is available on the nursing unit
D. Crush the tablet and mix it with other liquid medications for administration - CORRECT ANSWERS >>
A. Crush the tablet and mix it with water separately from other medications
A client with chronic asthma receives a prescription for montelukast, a leukotriene modifier. Which
statement by the client indicates to the nurse that medication teaching was effective?
A. I should take this medication only when I am having an asthma attack
B. I will take the tablet every evening to control my asthma
C. This medication will stop an asthma attack immediately
D. I will not need to use my inhalers twice a day when I start this medication - CORRECT ANSWERS >> B.
I will take the tablet every evening to control my asthma
The nurse is planning to administer the antiulcer GI agent sucralfate to a client with peptic ulcer disease.
Which action should the nurse include in this client's plan of care?
A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
D. Monitor for electrolyte imbalance - CORRECT ANSWERS >> C. Give sucralfate once a day, preferably
at bedtime
A client with anemia secondary to chronic kidney disease (CKD) started a prescription for epoetin alfa
two months ago. Which client finding best indicates that the medication is effective?
A. Reports of increased energy levels and decreased fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich foods
D. Hemoglobin level increased to 12 grams/dL (120 mmol/L) - CORRECT ANSWERS >> D. Hemoglobin
level increased to 12 grams/dL (120 mmol/L)
