TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY 16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1- 66/COMPLETE GUIDE

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE 2024-2025

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a hospital client who is
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having a computed tomography (CT) scan. The nursing attendant working
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on the oncology unit administers chemotherapy to hospital clients who
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have cancer. At the Public Health Department, a nursing attendant
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administers a measles-mumps-rubella (MMR) vaccine to a 14-month-old
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child as a routine immunization. Which branch of pharmacology best
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describes the actions of all three
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nursing attendants? P




A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- P B
Reasoning :->>>>>> P




Pharmacology is the study of the biologic effects of chemicals. Nursing P P P P P P P P P P



attendants are involved with clinical pharmacology or
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pharmacotherapeutics, which is a branch of pharmacology that deals with
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the uses of drugs to treat,prevent, and diagnose disease. The radiology
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nursing attendant is administering a drug to help diagnose a disease. The
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oncology nursing attendant is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and P P P P P P P P




pharmacokinetics is how the body acts on the body. P P P P P P P P




2. When involved in phase III drug evaluation studies, what
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responsibilities would the nursing attendant have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate hospital clients to be involved in the drug study
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C) Monitoring and observing hospital clients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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,ACCURATE CHOICE:-
P C
Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in which
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hospital clients are asked to record any symptoms they experience while
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taking the drugs. Nursing attendants may be responsible for helping collect
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and analyzethe information to be shared with the Food and Drug
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Administration (FDA)but would not conduct research independently
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because nursing attendants donot prescribe medications. Use of animals in
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drug testing is done in the preclinical trials. Select hospital clients who are
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involved in phase II studies to participate in studies where the participants
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have the disease the drug is intended to treat. These hospital clients are
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monitored closely for drug action and adverse effects. Phase I studies
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involve healthy human volunteers who are usually paid for their
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participation. Nursing attendants may observe for
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adverse effects and toxicity.
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3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
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The nursing attendant is aware this drug has a high abuse potential. Under
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what category would morphine be classified?
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A) Schedule I P




B) Schedule II P




C) Schedule III P




D) Schedule IV P




ACCURATE CHOICE:-
P B
Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
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Pbecause of severe dependence liability. Schedule I drugs have high abuse
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Ppotential and no accepted medical use. Schedule III drugs have a lesser
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Pabuse potential than II and an accepted medical use. Schedule IV drugs have
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low abuse potential and limited dependence liability.
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4. What concept is considered when generic drugs are substituted for brand
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name drugs?
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A) Bioavailability

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B) Critical concentration P




C) Distribution
D) Half-life
ACCURATE CHOICE:-AP




Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemic P P P P P P P P P P P P P



circulation and is available to act on body cells. Binders used in a generic
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drug may not be the same as those used in the brand name drug.
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Therefore, the way the body breaks down and uses the drug may differ,
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which may eliminate a generic drug substitution. Critical concentration is
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the amount ofa drug that is needed to cause a therapeutic effect and should
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not differ between generic and brand name medications. Distribution is
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the phase of pharmacokinetics, which involves the movement of a drug to
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the bodys tissues and is the same in generic and brand name drugs. A
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drugs half-life isthe time it takes for the amount of drug to decrease to
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half the peak level, which should not change when substituting a generic
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Pmedication.


5. A nursing attendant is assessing the hospital clients home medication use. After
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listening to the hospital client list current medications, the nursing
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Pattendant askswhat priority question? P P P P




A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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ACCURATE CHOICE:- P D
Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of
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Pover- the-counter medications because hospital clients may not consider
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Pthem important. The hospital client is unlikely to know the meaning of
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Porphan drugs unless they too are primary health care providers. Safety
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during pregnancy, use of a genericmedication, or classification of orphan
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Pdrugs are things the hospital client would be unable to answer but could
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Pbe found in reference books if the nursing attendant wishes to research
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them.
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