APHON Principles of Chemo and
Biotherapy Exam Questions and Answers
(Solved Papers)
Biotherapy - Correct Answers ✅Targeted anticancer agents
also known as biological response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what class - Correct
Answers ✅Biotherapy
Monoclonal antibodies (MoAbs) are what class - Correct
Answers ✅Biotherapy
Define pharmacokinetics - Correct Answers ✅Study of drug
absorption, metabolism, and excretion
Define pharmacodynamics - Correct Answers ✅The
concentration of the drug in the body and how it produces a
response
Define adjuvant chemotherapy - Correct Answers ✅The
use of chemo after another type of therapy, such as surgery,
to treat residual disease or undetectable metastasis.
Define neoadjuvant chemotherapy - Correct Answers
✅When chemo is used preoperatively to decrease tumor
burden in order to make it easier to remove the tumor
surgically.
, APHON Principles of Chemo and
Biotherapy Exam Questions and Answers
(Solved Papers)
Define sanctuary sites - Correct Answers ✅Sites within the
body where tumor cells sequester and are not easily reached
by chemo such as the CNS
What normal cells are most often effected by chemotherapy -
Correct Answers ✅Hematopoietic, mucosal (mouth & GI),
hair follicles
Why use chemotherapy - Correct Answers ✅To prevent
cancer cells from dividing, metastasizing, and ultimately
causing the death of the patient
Cure - Correct Answers ✅To permanently eradicate the
cancer
Control - Correct Answers ✅To extend the length & QOL
when cure is not feasible or realistic
Palliation - Correct Answers ✅Minimize pain and suffering
during end of life
Resting phase of cell cycle - Correct Answers ✅Gap 0 -
cells not dividing
Biotherapy Exam Questions and Answers
(Solved Papers)
Biotherapy - Correct Answers ✅Targeted anticancer agents
also known as biological response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what class - Correct
Answers ✅Biotherapy
Monoclonal antibodies (MoAbs) are what class - Correct
Answers ✅Biotherapy
Define pharmacokinetics - Correct Answers ✅Study of drug
absorption, metabolism, and excretion
Define pharmacodynamics - Correct Answers ✅The
concentration of the drug in the body and how it produces a
response
Define adjuvant chemotherapy - Correct Answers ✅The
use of chemo after another type of therapy, such as surgery,
to treat residual disease or undetectable metastasis.
Define neoadjuvant chemotherapy - Correct Answers
✅When chemo is used preoperatively to decrease tumor
burden in order to make it easier to remove the tumor
surgically.
, APHON Principles of Chemo and
Biotherapy Exam Questions and Answers
(Solved Papers)
Define sanctuary sites - Correct Answers ✅Sites within the
body where tumor cells sequester and are not easily reached
by chemo such as the CNS
What normal cells are most often effected by chemotherapy -
Correct Answers ✅Hematopoietic, mucosal (mouth & GI),
hair follicles
Why use chemotherapy - Correct Answers ✅To prevent
cancer cells from dividing, metastasizing, and ultimately
causing the death of the patient
Cure - Correct Answers ✅To permanently eradicate the
cancer
Control - Correct Answers ✅To extend the length & QOL
when cure is not feasible or realistic
Palliation - Correct Answers ✅Minimize pain and suffering
during end of life
Resting phase of cell cycle - Correct Answers ✅Gap 0 -
cells not dividing
