CHEMOTHERAPY AND BIOTHERAPY
GUIDELINES - ONS 942P QUESTIONS
AND ANSWERS WITH COMPLETE
SOLUTIONS 100% CORRECT!!!
nadir -ANSWER✔✔lowest blood cell count after chemotherapy, 10-14 days but
varies with individual agents
cisplatin -ANSWER✔✔ototoxic --> report tinnitus
nephrotoxic --> monitor BUN and creatinine
depletes K and Mg --> replacement prior/after
cytoxan -ANSWER✔✔hemorrhagic cystitis
>3000ml/day fluid intake unless contraindicated
void q2-4 hours day, q4 hours night
can also cause sinus drainage, slow infusion
oxaliplatin -ANSWER✔✔hang with D5W
cold sensitivity
(Ixnay on the ice, okay?)
irinotecan -ANSWER✔✔diarrhea
(I run to the can)
nephrotoxic -ANSWER✔✔avastin - protein in urine
cisplatin
, zometa
hypersensitivity reactions -ANSWER✔✔taxol
rituxan and other MAbs
herceptin
zometa -ANSWER✔✔know creatinine prior
run over at least 15 mins
osteonecrosis of jaw
taxol -ANSWER✔✔titrate first couple doses
peripheral neuropathy
cryotherapy
need filtered line
(Are YEW going to react?)
avastin -ANSWER✔✔MAb - angiogenesis inhibitor
colorectal, kidney, cervical, NSCLC, brain
HTN, proteinuria
can affect healing; hold 4 weeks prior to/after surgery
cardiotoxic -ANSWER✔✔adriamycin/doxorubicin
herceptin
kadcyla
perjeta
GUIDELINES - ONS 942P QUESTIONS
AND ANSWERS WITH COMPLETE
SOLUTIONS 100% CORRECT!!!
nadir -ANSWER✔✔lowest blood cell count after chemotherapy, 10-14 days but
varies with individual agents
cisplatin -ANSWER✔✔ototoxic --> report tinnitus
nephrotoxic --> monitor BUN and creatinine
depletes K and Mg --> replacement prior/after
cytoxan -ANSWER✔✔hemorrhagic cystitis
>3000ml/day fluid intake unless contraindicated
void q2-4 hours day, q4 hours night
can also cause sinus drainage, slow infusion
oxaliplatin -ANSWER✔✔hang with D5W
cold sensitivity
(Ixnay on the ice, okay?)
irinotecan -ANSWER✔✔diarrhea
(I run to the can)
nephrotoxic -ANSWER✔✔avastin - protein in urine
cisplatin
, zometa
hypersensitivity reactions -ANSWER✔✔taxol
rituxan and other MAbs
herceptin
zometa -ANSWER✔✔know creatinine prior
run over at least 15 mins
osteonecrosis of jaw
taxol -ANSWER✔✔titrate first couple doses
peripheral neuropathy
cryotherapy
need filtered line
(Are YEW going to react?)
avastin -ANSWER✔✔MAb - angiogenesis inhibitor
colorectal, kidney, cervical, NSCLC, brain
HTN, proteinuria
can affect healing; hold 4 weeks prior to/after surgery
cardiotoxic -ANSWER✔✔adriamycin/doxorubicin
herceptin
kadcyla
perjeta
