MICROBIO Chapter 18
1. integument: - skin
- hair
- nails
- sweat and oil glands
2. epidermis: - stratum corneum
- packaged with keratin (withstand damage and abrasion)
- stratum basale: basal layer (contains all cells)
3. dermis: - connective tissue
- dense network of nerves, blood vessels, and lymphatic vessels
- damage results in bleeding
- blister formation
4. follies: - roots of hair located in dermis
- sebaceous oil glands and scent glands are associated with follicle
- sweat glands are separate from follicle
1/6
, 5. antimicrobial peptides: - in epithelial cells
- positively charged chemicals that act by disrupting negatively charged membranes of bacteria
6. sebum: - secreted by sebaceous glands
- low pH makes skin inhospitable to most microorganisms
- high concentration of lipids serve as nutrients for normal microbiota
- breakdown of fatty acids leads to toxic byproducts that inhibit growth of other microbes not adapted to the skin
7. sweat: low pH and high salt concentration inhibit microbes
8. lysozyme: - enzyme found in sweat, tears, and saliva
- specifically breaks down peptidoglycan
9. acne: - all follicle-associated lesions
2/6
1. integument: - skin
- hair
- nails
- sweat and oil glands
2. epidermis: - stratum corneum
- packaged with keratin (withstand damage and abrasion)
- stratum basale: basal layer (contains all cells)
3. dermis: - connective tissue
- dense network of nerves, blood vessels, and lymphatic vessels
- damage results in bleeding
- blister formation
4. follies: - roots of hair located in dermis
- sebaceous oil glands and scent glands are associated with follicle
- sweat glands are separate from follicle
1/6
, 5. antimicrobial peptides: - in epithelial cells
- positively charged chemicals that act by disrupting negatively charged membranes of bacteria
6. sebum: - secreted by sebaceous glands
- low pH makes skin inhospitable to most microorganisms
- high concentration of lipids serve as nutrients for normal microbiota
- breakdown of fatty acids leads to toxic byproducts that inhibit growth of other microbes not adapted to the skin
7. sweat: low pH and high salt concentration inhibit microbes
8. lysozyme: - enzyme found in sweat, tears, and saliva
- specifically breaks down peptidoglycan
9. acne: - all follicle-associated lesions
2/6
