GMS 6540 Homework exam with correct |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answers
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Genetic changes are required for which of the following to occur? Select all that apply. - correct
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answer✔✔Initiation/Transformation of a cell
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Formation of a malignant tumor from a pre-neoplastic lesion |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Formation of clinical cancer from a malignant tumor |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Metastasis of a clinical cancer |||\\\ |||\\\ |||\\\ |||\\\
What effect would a G12V mutation in Ras have on ERK? - correct answer✔✔It would lead to
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increased activation of ERK |||\\\ |||\\\ |||\\\
Are cancers more likely to develop mutation that activate or inactivate Rb? - correct
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answer✔✔Inactivate
Metabolites of nicotine commonly result in DNA point mutations. Which type of DNA instability |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
is this an example of? - correct answer✔✔Genetic instability
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If a human cell underwent endoreduplication followed by failed cytokinesis, how many
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
chromosomes would you expect that cell to now contain? - correct answer✔✔184 |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Which of the following statements is true regarding apoptosis. - correct answer✔✔Cancer
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cells must avoid it |||\\\ |||\\\ |||\\\
Which statement best describes the Warburg effect? - correct answer✔✔The switching of
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
cancer cells from oxidative phosphorylation to aerobic glycolysis |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
, A patient undergoes an FdG-PET scan. Will a tumor contain more or less 18fluorodeoxyglucose
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
than normal the surrounding tissue? - correct answer✔✔More
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Angiogenesis is __________________. - correct answer✔✔the process of creating new blood |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
vessels from current blood vessels |||\\\ |||\\\ |||\\\ |||\\\
Is inflammation harmful or beneficial to cancer? - correct answer✔✔Beneficial
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If a cell expresses a mutant form of EGFR, would this be considered a tumor specific antigen or
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
a tumor associated antigen? - correct answer✔✔Tumor specific antigen
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Which statement best describes how cancer cells overcome the Hayflick limit? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔They upregulate telomerase |||\\\ |||\\\
What chemical causes the most cigarette-related DNA mutations? - correct
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answer✔✔Benzo[a]pyrene
The Epstein-Barr virus, most famous for causing mononucleosis, also plays a prevalent role in
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
the formation of what type of cancer? - correct answer✔✔Burkitt's lymphoma
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What viral protein is capable of inhibiting p53? - correct answer✔✔E6
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Which class of cancer drugs is the least selective towards cancer cells? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Chemotherapy
Is chemotherapy generally more effective when tumors are small or large? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Small
answers
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Genetic changes are required for which of the following to occur? Select all that apply. - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Initiation/Transformation of a cell
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Formation of a malignant tumor from a pre-neoplastic lesion |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Formation of clinical cancer from a malignant tumor |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Metastasis of a clinical cancer |||\\\ |||\\\ |||\\\ |||\\\
What effect would a G12V mutation in Ras have on ERK? - correct answer✔✔It would lead to
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
increased activation of ERK |||\\\ |||\\\ |||\\\
Are cancers more likely to develop mutation that activate or inactivate Rb? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Inactivate
Metabolites of nicotine commonly result in DNA point mutations. Which type of DNA instability |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
is this an example of? - correct answer✔✔Genetic instability
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
If a human cell underwent endoreduplication followed by failed cytokinesis, how many
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
chromosomes would you expect that cell to now contain? - correct answer✔✔184 |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Which of the following statements is true regarding apoptosis. - correct answer✔✔Cancer
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
cells must avoid it |||\\\ |||\\\ |||\\\
Which statement best describes the Warburg effect? - correct answer✔✔The switching of
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
cancer cells from oxidative phosphorylation to aerobic glycolysis |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
, A patient undergoes an FdG-PET scan. Will a tumor contain more or less 18fluorodeoxyglucose
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
than normal the surrounding tissue? - correct answer✔✔More
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Angiogenesis is __________________. - correct answer✔✔the process of creating new blood |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
vessels from current blood vessels |||\\\ |||\\\ |||\\\ |||\\\
Is inflammation harmful or beneficial to cancer? - correct answer✔✔Beneficial
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
If a cell expresses a mutant form of EGFR, would this be considered a tumor specific antigen or
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
a tumor associated antigen? - correct answer✔✔Tumor specific antigen
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Which statement best describes how cancer cells overcome the Hayflick limit? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔They upregulate telomerase |||\\\ |||\\\
What chemical causes the most cigarette-related DNA mutations? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Benzo[a]pyrene
The Epstein-Barr virus, most famous for causing mononucleosis, also plays a prevalent role in
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
the formation of what type of cancer? - correct answer✔✔Burkitt's lymphoma
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
What viral protein is capable of inhibiting p53? - correct answer✔✔E6
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
Which class of cancer drugs is the least selective towards cancer cells? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Chemotherapy
Is chemotherapy generally more effective when tumors are small or large? - correct
|||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\ |||\\\
answer✔✔Small
