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Samenvatting H19 Protozoa

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H19 protozoa zelfgeschreven cursus/samenvatting !! best in bundel te kopen

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🦟
19 protozoa
= 1-cellige dieren
vnl tropische regio’s, meestal aseksuele voortplanting
Meeste problemen zijn bij zwakke immuunrespons

meestal IC, afgewisseld met migrerende stadia
verscheidene ontwijkingsstrategiën

transmisie kan: per os (!), seksueel, of met insecten



trypanosomen:
slaapziekte, in tsetsevlieg → is gastheer, als ook de mens; overdracht via bloed

leishmaniasis:
zandvlieg en mens als gastheer; overdracht via bloed

entamoebiasis:

GI kanaal
cryptosporiodosis:

wereldwijd

GI kanaal, via water en voedsel cysten; diarree
Toxoplasmose:


in kat → oöcyste (blijft tot 1.5j infectieus) via stoelgang → inslikken: sneldelende
tachyzoïeten liften met leukocyten en invaderen weefsels → weefselcysten, mgls
transplacentaire invasie

replicatie w gecontroleerd dr macrofagen, humorale en cellulaire immuniteit → dormante en niet-
inflammogene weefselcysten

vooral in hersenen, retina en spieren
onschuldig tenzij immuungedeprimeerd of zwanger (foetus is immuungedeprimeerd)
→ 90-90% asymptomatisch en persistentie
→ aangetast kind: convulsies, microcephalie, hydrocephalie, mentale achterstand, vermidnerde visus,
hepatosplenomegalie. W vaak pas laat ontdekt (jaren). Hoe vroeger in de zwangerschap hoe meer schade

→ vermijden rauw vlees, zelf geteelde groenten etc. Koken verneitigd de cysten
diagnostiek
IgG vr vorig contact, IgM vr acute infectie (soms IgA, blijft korter)

eventueel PCR vruchtwater indien overweging abortus
Malaria:
Plasmodium spp.


via mug op mens → via bloed nr lever → IC replicatie en vrijstellen merozoieten die
erythrocyten infecteren en er in repliceren




19 protozoa 1

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October 1, 2025
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Written in
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