COMSAE Phase 1 Form 104 practice
Exam With Actual 120 Questions &
Verified Answers,Plus
Rationales/Expert Verified For
Guaranteed Pass Graded A+/
2025/2026 /Latest Update/Instant
Download Pdf
1. A 25-year-old man presents with fatigue and pallor. Lab results show Hb 9 g/dL, MCV
70 fL, and ferritin 8 ng/mL. What is the most likely diagnosis?
A) Vitamin B12 deficiency
B) Iron deficiency anemia
C) Thalassemia minor
D) Aplastic anemia
B) Iron deficiency anemia
Rationale: Microcytic anemia (low MCV) with low ferritin indicates iron deficiency anemia,
commonly due to blood loss or poor dietary intake.
2. A patient with chronic hypertension develops sudden severe headache, vomiting,
and neurological deficits. What is the most likely diagnosis?
A) Ischemic stroke
B) Subarachnoid hemorrhage
C) Intracerebral hemorrhage
D) Migraine
C) Intracerebral hemorrhage
Rationale: Sudden headache with neurological deficits in a hypertensive patient suggests
intracerebral hemorrhage.
3. Which of the following is the most common cause of community-acquired
pneumonia in adults?
A) Staphylococcus aureus
, B) Streptococcus pneumoniae
C) Haemophilus influenzae
D) Mycoplasma pneumoniae
B) Streptococcus pneumoniae
Rationale: Streptococcus pneumoniae is the leading cause of community-acquired
pneumonia in adults.
4. A 35-year-old woman presents with fatigue, weight gain, and constipation. Lab shows
elevated TSH and low free T4. What is the diagnosis?
A) Hyperthyroidism
B) Subclinical hypothyroidism
C) Primary hypothyroidism
D) Secondary hypothyroidism
C) Primary hypothyroidism
Rationale: Elevated TSH with low T4 indicates primary hypothyroidism, typically due to
autoimmune thyroiditis.
5. Which of the following antibiotics is first-line treatment for uncomplicated urinary
tract infection in a non-pregnant adult woman?
A) Ciprofloxacin
B) Nitrofurantoin
C) Amoxicillin-clavulanate
D) Vancomycin
B) Nitrofurantoin
Rationale: Nitrofurantoin is effective and safe for uncomplicated UTIs in non-pregnant
adult women.
6. A 60-year-old man with chronic alcohol use presents with confusion, ataxia, and
ophthalmoplegia. What is the most likely diagnosis?
A) Korsakoff syndrome
B) Wernicke encephalopathy
C) Alcoholic hepatitis
D) Hepatic encephalopathy
B) Wernicke encephalopathy
Rationale: The classic triad of confusion, ataxia, and ophthalmoplegia is characteristic of
Wernicke encephalopathy due to thiamine deficiency.
7. Which of the following is a risk factor for developing deep vein thrombosis?
A) Hypotension
B) Immobility
, C) Hyperthyroidism
D) Asthma
B) Immobility
Rationale: Prolonged immobility promotes venous stasis, a major risk factor for DVT.
8. A 22-year-old woman presents with fever, dysuria, and flank pain. Urinalysis shows
pyuria and bacteriuria. What is the best initial management?
A) Oral antibiotics
B) Hospitalization for IV antibiotics
C) Bladder catheterization
D) Observation only
A) Oral antibiotics
Rationale: For uncomplicated pyelonephritis in an otherwise healthy adult, oral antibiotics
are appropriate initial management.
9. Which of the following is the most sensitive test for diagnosing pulmonary
embolism?
A) Chest X-ray
B) ECG
C) D-dimer
D) CT pulmonary angiography
D) CT pulmonary angiography
Rationale: CT pulmonary angiography is the gold standard and most sensitive imaging test
for pulmonary embolism.
10. A 40-year-old woman presents with joint pain, malar rash, and photosensitivity.
Which antibody is most specific for her condition?
A) Anti-dsDNA
B) Anti-Ro/SSA
C) Anti-La/SSB
D) Rheumatoid factor
A) Anti-dsDNA
Rationale: Anti-dsDNA antibodies are highly specific for systemic lupus erythematosus.
11. Which of the following is a contraindication to live vaccines?
A) Mild cold
B) Pregnancy
C) History of chickenpox
D) Prior influenza vaccination
B) Pregnancy
Rationale: Live vaccines are contraindicated in pregnancy due to risk of fetal infection.
Exam With Actual 120 Questions &
Verified Answers,Plus
Rationales/Expert Verified For
Guaranteed Pass Graded A+/
2025/2026 /Latest Update/Instant
Download Pdf
1. A 25-year-old man presents with fatigue and pallor. Lab results show Hb 9 g/dL, MCV
70 fL, and ferritin 8 ng/mL. What is the most likely diagnosis?
A) Vitamin B12 deficiency
B) Iron deficiency anemia
C) Thalassemia minor
D) Aplastic anemia
B) Iron deficiency anemia
Rationale: Microcytic anemia (low MCV) with low ferritin indicates iron deficiency anemia,
commonly due to blood loss or poor dietary intake.
2. A patient with chronic hypertension develops sudden severe headache, vomiting,
and neurological deficits. What is the most likely diagnosis?
A) Ischemic stroke
B) Subarachnoid hemorrhage
C) Intracerebral hemorrhage
D) Migraine
C) Intracerebral hemorrhage
Rationale: Sudden headache with neurological deficits in a hypertensive patient suggests
intracerebral hemorrhage.
3. Which of the following is the most common cause of community-acquired
pneumonia in adults?
A) Staphylococcus aureus
, B) Streptococcus pneumoniae
C) Haemophilus influenzae
D) Mycoplasma pneumoniae
B) Streptococcus pneumoniae
Rationale: Streptococcus pneumoniae is the leading cause of community-acquired
pneumonia in adults.
4. A 35-year-old woman presents with fatigue, weight gain, and constipation. Lab shows
elevated TSH and low free T4. What is the diagnosis?
A) Hyperthyroidism
B) Subclinical hypothyroidism
C) Primary hypothyroidism
D) Secondary hypothyroidism
C) Primary hypothyroidism
Rationale: Elevated TSH with low T4 indicates primary hypothyroidism, typically due to
autoimmune thyroiditis.
5. Which of the following antibiotics is first-line treatment for uncomplicated urinary
tract infection in a non-pregnant adult woman?
A) Ciprofloxacin
B) Nitrofurantoin
C) Amoxicillin-clavulanate
D) Vancomycin
B) Nitrofurantoin
Rationale: Nitrofurantoin is effective and safe for uncomplicated UTIs in non-pregnant
adult women.
6. A 60-year-old man with chronic alcohol use presents with confusion, ataxia, and
ophthalmoplegia. What is the most likely diagnosis?
A) Korsakoff syndrome
B) Wernicke encephalopathy
C) Alcoholic hepatitis
D) Hepatic encephalopathy
B) Wernicke encephalopathy
Rationale: The classic triad of confusion, ataxia, and ophthalmoplegia is characteristic of
Wernicke encephalopathy due to thiamine deficiency.
7. Which of the following is a risk factor for developing deep vein thrombosis?
A) Hypotension
B) Immobility
, C) Hyperthyroidism
D) Asthma
B) Immobility
Rationale: Prolonged immobility promotes venous stasis, a major risk factor for DVT.
8. A 22-year-old woman presents with fever, dysuria, and flank pain. Urinalysis shows
pyuria and bacteriuria. What is the best initial management?
A) Oral antibiotics
B) Hospitalization for IV antibiotics
C) Bladder catheterization
D) Observation only
A) Oral antibiotics
Rationale: For uncomplicated pyelonephritis in an otherwise healthy adult, oral antibiotics
are appropriate initial management.
9. Which of the following is the most sensitive test for diagnosing pulmonary
embolism?
A) Chest X-ray
B) ECG
C) D-dimer
D) CT pulmonary angiography
D) CT pulmonary angiography
Rationale: CT pulmonary angiography is the gold standard and most sensitive imaging test
for pulmonary embolism.
10. A 40-year-old woman presents with joint pain, malar rash, and photosensitivity.
Which antibody is most specific for her condition?
A) Anti-dsDNA
B) Anti-Ro/SSA
C) Anti-La/SSB
D) Rheumatoid factor
A) Anti-dsDNA
Rationale: Anti-dsDNA antibodies are highly specific for systemic lupus erythematosus.
11. Which of the following is a contraindication to live vaccines?
A) Mild cold
B) Pregnancy
C) History of chickenpox
D) Prior influenza vaccination
B) Pregnancy
Rationale: Live vaccines are contraindicated in pregnancy due to risk of fetal infection.
