CORRECT AND WELL DETAILED
ANSWERS|LATEST 2025/2026|GRADED
Acute symptoms of diabetes plus casual plasma glucose concentration greater than or equal t
B B B B B B B B B B B B B
o 200 mg/dL.
B B
*Casual is defined as any time of day without regard to time since last meal. The classic sympt
B B B B B B B B B B B B B B B B B
oms of diabetes are polyuria, polydipsia, and unexplained weight loss.
B B B B B B B B B
a. Pre-diabetes
B
b. Diabetes mellitus - ANSWER
B B B B b
Fasting plasma glucose greater than or equal to 126 mg/dL.
B B B B B B B B B
*Fasting is defined as no caloric intake for at least 8 hours.
B B B B B B B B B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B a
2 hour post-
B B
load plasma glucose in an oral glucose tolerance test greater than or equal to 200 mg/dL. The t
B B B B B B B B B B B B B B B B B
est uses a glucose load containing the equivalent of 75 g anhydrous glucose dissolved in water.
B B B B B B B B B B B B B B B
a. Pre-diabetes
B
b. Diabetes mellitus - ANSWER
B B B B b
HgbA1c greater than or equal to 6.5%
B B B B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B a
Fasting plasma glucose 100 to 125 mg/dL (IFG) or
B B B B B B B B
a. Diabetes mellitus
B B
1
,b. Pre-diabetes - ANSWER
B B B b
Plasma glucose 140 to 199 mg/dL (IGT) 2 hours post-
B B B B B B B B B
ingestion of standard glucose load (75 g) or
B B B B B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B b
HgbA1c 5.7% to 6.4% B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B b
SGLT2i (sodium-glucose cotransporter-2 inhibitors) - ANSWER
B B B B B -ozin
Biguanides - ANSWER B B Metformin (Glucophage) B
DPP-4i (Dipeptidyl Peptidase-4 Inhibitors) - ANSWER
B B B B B - iptin
B
Sulfonylureas - ANSWER B B - Gly or Gli
B B B
GLP-1 (Glucagon-like peptide 1 receptor agonists) - ANSWER
B B B B B B B - glutides
B
TZD (Thiazolidinediones) - ANSWER
B B B - azone
B
Rapid onset insulin - ANSWER
B B B B aspart (Novolog), glulisine (apidra) and lispro (humalog)
B B B B B B
Rapid acting onset - ANSWER
B B B B 5-30 minutes B
2
,rapid acting peak - ANSWER
B B B B 0.5 - 3 hours
B B B
rapid acting duration - ANSWER
B B B B 3-4 hours
B
short acting insulin - ANSWER
B B B B Regular (Humulin R, Novolin R)
B B B B
short acting onset - ANSWER
B B B B 30-60 min B
short acting peak - ANSWER
B B B B 2-4 h
B
short acting duration - ANSWER
B B B B 3-7 h B
intermediate acting insulin - ANSWER
B B B B Isophane (NPH) B
intermediate acting onset - ANSWER
B B B B 1-2 hours
B
intermediate acting peak - ANSWER
B B B B 4-10 hours B
intermediate acting duration - ANSWER
B B B B 10-16 h B
long acting insulin - ANSWER
B B B B glargine (Lantus)
B
detemir (Levemir)
B
long acting onset - ANSWER
B B B B 1-2 hours
B
long acting peak - ANSWER
B B B B none
3
, long acting duration - ANSWER
B B B B 20-24 h B
fixed combination insulin - ANSWER
B B B B NPH mixed with regular or lisper or aspirate
B B B B B B B
fixed combination onset - ANSWER
B B B B 5-60 minutes B
fixed combination peak - ANSWER
B B B B dual
fixed combination duration - ANSWER
B B B B 16 h B
TSH is low, free T4 is high and T3 is normal -
B B B B B B B B B B B
BANSWER Etiology can be related to exogenous T4 ingestion, a concurrent non- B B B B B B B B B B
thyroidal illness, or amiodarone-induced thyroid dysfunction.
B B B B B
Serum TSH is normal or elevated, and free T4 and T3 are elevated -
B B B B B B B B B B B B B
BANSWER Possibility of a TSH producing pituitary tumor, which would need to be evalua B B B B B B B B B B B B
ted further with magnetic resonance imaging.
B B B B B
TSH is low, the free T4 is normal and the serum T3 is high -
B B B B B B B B B B B B B B
BANSWER Primary hyperthyroidism. However, other reasons for this thyroid function tes B B B B B B B B B
t abnormality could be exogenous T3 ingestion, or a functioning adenoma.
B B B B B B B B B B
Which of the following agents is the first-
B B B B B B B
line treatment for hyperthyroidism or Grave's disease?
B B B B B B
a. Metoprolol
B
b. Methimazole
B
c. Allopurinol
B
d. Levothyroxine - ANSWER
B B B b
4
ANSWERS|LATEST 2025/2026|GRADED
Acute symptoms of diabetes plus casual plasma glucose concentration greater than or equal t
B B B B B B B B B B B B B
o 200 mg/dL.
B B
*Casual is defined as any time of day without regard to time since last meal. The classic sympt
B B B B B B B B B B B B B B B B B
oms of diabetes are polyuria, polydipsia, and unexplained weight loss.
B B B B B B B B B
a. Pre-diabetes
B
b. Diabetes mellitus - ANSWER
B B B B b
Fasting plasma glucose greater than or equal to 126 mg/dL.
B B B B B B B B B
*Fasting is defined as no caloric intake for at least 8 hours.
B B B B B B B B B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B a
2 hour post-
B B
load plasma glucose in an oral glucose tolerance test greater than or equal to 200 mg/dL. The t
B B B B B B B B B B B B B B B B B
est uses a glucose load containing the equivalent of 75 g anhydrous glucose dissolved in water.
B B B B B B B B B B B B B B B
a. Pre-diabetes
B
b. Diabetes mellitus - ANSWER
B B B B b
HgbA1c greater than or equal to 6.5%
B B B B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B a
Fasting plasma glucose 100 to 125 mg/dL (IFG) or
B B B B B B B B
a. Diabetes mellitus
B B
1
,b. Pre-diabetes - ANSWER
B B B b
Plasma glucose 140 to 199 mg/dL (IGT) 2 hours post-
B B B B B B B B B
ingestion of standard glucose load (75 g) or
B B B B B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B b
HgbA1c 5.7% to 6.4% B B B
a. Diabetes mellitus
B B
b. Pre-diabetes - ANSWER
B B B b
SGLT2i (sodium-glucose cotransporter-2 inhibitors) - ANSWER
B B B B B -ozin
Biguanides - ANSWER B B Metformin (Glucophage) B
DPP-4i (Dipeptidyl Peptidase-4 Inhibitors) - ANSWER
B B B B B - iptin
B
Sulfonylureas - ANSWER B B - Gly or Gli
B B B
GLP-1 (Glucagon-like peptide 1 receptor agonists) - ANSWER
B B B B B B B - glutides
B
TZD (Thiazolidinediones) - ANSWER
B B B - azone
B
Rapid onset insulin - ANSWER
B B B B aspart (Novolog), glulisine (apidra) and lispro (humalog)
B B B B B B
Rapid acting onset - ANSWER
B B B B 5-30 minutes B
2
,rapid acting peak - ANSWER
B B B B 0.5 - 3 hours
B B B
rapid acting duration - ANSWER
B B B B 3-4 hours
B
short acting insulin - ANSWER
B B B B Regular (Humulin R, Novolin R)
B B B B
short acting onset - ANSWER
B B B B 30-60 min B
short acting peak - ANSWER
B B B B 2-4 h
B
short acting duration - ANSWER
B B B B 3-7 h B
intermediate acting insulin - ANSWER
B B B B Isophane (NPH) B
intermediate acting onset - ANSWER
B B B B 1-2 hours
B
intermediate acting peak - ANSWER
B B B B 4-10 hours B
intermediate acting duration - ANSWER
B B B B 10-16 h B
long acting insulin - ANSWER
B B B B glargine (Lantus)
B
detemir (Levemir)
B
long acting onset - ANSWER
B B B B 1-2 hours
B
long acting peak - ANSWER
B B B B none
3
, long acting duration - ANSWER
B B B B 20-24 h B
fixed combination insulin - ANSWER
B B B B NPH mixed with regular or lisper or aspirate
B B B B B B B
fixed combination onset - ANSWER
B B B B 5-60 minutes B
fixed combination peak - ANSWER
B B B B dual
fixed combination duration - ANSWER
B B B B 16 h B
TSH is low, free T4 is high and T3 is normal -
B B B B B B B B B B B
BANSWER Etiology can be related to exogenous T4 ingestion, a concurrent non- B B B B B B B B B B
thyroidal illness, or amiodarone-induced thyroid dysfunction.
B B B B B
Serum TSH is normal or elevated, and free T4 and T3 are elevated -
B B B B B B B B B B B B B
BANSWER Possibility of a TSH producing pituitary tumor, which would need to be evalua B B B B B B B B B B B B
ted further with magnetic resonance imaging.
B B B B B
TSH is low, the free T4 is normal and the serum T3 is high -
B B B B B B B B B B B B B B
BANSWER Primary hyperthyroidism. However, other reasons for this thyroid function tes B B B B B B B B B
t abnormality could be exogenous T3 ingestion, or a functioning adenoma.
B B B B B B B B B B
Which of the following agents is the first-
B B B B B B B
line treatment for hyperthyroidism or Grave's disease?
B B B B B B
a. Metoprolol
B
b. Methimazole
B
c. Allopurinol
B
d. Levothyroxine - ANSWER
B B B b
4