Maryville University Nursing 615 Exam
3 Review Questions with Correct
Answers
Low-dose colchine - ANSWERS1.2 mg at first sign of flare, followed by 0.6 mg one hour
later for a total dose of 1.8 mg.
High-dose colchine - ANSWERS1.2 mg followed by 0.6 mg every 4-6 hours totaling 4.8
mg.
Gout - ANSWERSBUN, creatinine, and creatinine clearance should be monitored in the
treatment of this disease
Colchine - ANSWERSThis medication can cause severe diarrhea, nausea, vomiting,
abdominal pain
Febuxostat (Uloric) - ANSWERSWhen prescribing this medication, patients should be
taught that gout may worsen with therapy before it improves
Corticosteroids - ANSWERSThese medications can cause the following adverse effects
if taken for six months or more: Osteoporosis and poor diabetic control. Patients should
report black, tarry stools or abdominal pain.
Corticosteroids - ANSWERSThese medications should be tapered to avoid recurrent
activity of the underlying disease and possible cortisol deficiency resulting from the
hypothalamic-pituitary-adrenal axis suppression during the period of steroid therapy.
Black Box Warning on NSAIDS - ANSWERSIncreased risk of serious cardiovascular
thrombotic events, such as myocardial infarction and stroke. These medications can
also cause serious GI events such as bleeding, ulceration or perforation of stomach or
intestines, which can be fatal.
Pain management - ANSWERSWhen treating this common issue, it is recommended to
begin with NSAIDS and work up from there as needed
Ibuprofen - ANSWERSThis medication works by inhibiting the COX enzymes; however,
the exact mechanism of action for this particular medication is unknown.
Acetaminophen - ANSWERSA serious adverse effect related to this medication is
referred to as "------------- poisoning"
, Symptoms of hypoglycemia - ANSWERSDecreased LOC, hunger, diaphoresis,
weakness, dizziness and tachycardia
Symptoms of hyperglycemia - ANSWERSPolyuria, polydipsia and polyphagia (weight
loss)
Symptoms of DKA - ANSWERSKussmaul's respiration, ketone odor of the breath (fruity
breath), vomiting, dehydration, abdominal pain, and neurologic symptoms such as
lethargy; can progress to coma in later stages if left untreated.
Metformin - ANSWERSThis medication decreases hepatic glucose output inhibiting
gluconeogenesis. It also increases insulin mediated glucose utilization in peripheral
tissues. This medication decreases intestinal absorption of glucose. This medication
may also be used in diabetics to decrease cholesterol and triglyceride levels.
Metformin - ANSWERSWhen patients are prescribed this medication, the primary care
provider should assess serum creatinine, renal function, and creatinine clearance
initially and annually.
Gliptins (DPP4 inhibitors) - ANSWERSThese medications increase the incretin levels,
which inhibit glucagon release; this subsequently increases insulin secretion, decreases
gastric emptying and decreases blood glucose levels.
GLP-1 agonists - ANSWERSThese medications bind directly to the GLP-1 receptor,
which then slows gastric emptying and increases insulin secretion by pancreatic beta
cells.
Exenatide (Byetta) - ANSWERSThis medication should be administered 60 minutes
before breakfast and dinner.
PTU - ANSWERSAdverse effects of this medication include fatal granuloctyopenia
(presents as fever and slow throat), vasculitis, temporary alopecia, rash, aplastic
anemia, and acute renal failure.
Levothyroxine - ANSWERSAdverse effects of this medication include tachycardia and
angina, which are more noticable in the elderly.
Methimazole - ANSWERSThis medication is the recommended treatment of toxic goiter
Methimazole - ANSWERSThis medication is tetratogenic and may cause the fetus to
get aplasia acutis.
PTU - ANSWERSAdverse effects of this medication includes fatal granuloctyopenia
(presents as fever and slow throat), vasculitis, temporary alopecia, rash, aplastic
anemia, and acute renal failure.
3 Review Questions with Correct
Answers
Low-dose colchine - ANSWERS1.2 mg at first sign of flare, followed by 0.6 mg one hour
later for a total dose of 1.8 mg.
High-dose colchine - ANSWERS1.2 mg followed by 0.6 mg every 4-6 hours totaling 4.8
mg.
Gout - ANSWERSBUN, creatinine, and creatinine clearance should be monitored in the
treatment of this disease
Colchine - ANSWERSThis medication can cause severe diarrhea, nausea, vomiting,
abdominal pain
Febuxostat (Uloric) - ANSWERSWhen prescribing this medication, patients should be
taught that gout may worsen with therapy before it improves
Corticosteroids - ANSWERSThese medications can cause the following adverse effects
if taken for six months or more: Osteoporosis and poor diabetic control. Patients should
report black, tarry stools or abdominal pain.
Corticosteroids - ANSWERSThese medications should be tapered to avoid recurrent
activity of the underlying disease and possible cortisol deficiency resulting from the
hypothalamic-pituitary-adrenal axis suppression during the period of steroid therapy.
Black Box Warning on NSAIDS - ANSWERSIncreased risk of serious cardiovascular
thrombotic events, such as myocardial infarction and stroke. These medications can
also cause serious GI events such as bleeding, ulceration or perforation of stomach or
intestines, which can be fatal.
Pain management - ANSWERSWhen treating this common issue, it is recommended to
begin with NSAIDS and work up from there as needed
Ibuprofen - ANSWERSThis medication works by inhibiting the COX enzymes; however,
the exact mechanism of action for this particular medication is unknown.
Acetaminophen - ANSWERSA serious adverse effect related to this medication is
referred to as "------------- poisoning"
, Symptoms of hypoglycemia - ANSWERSDecreased LOC, hunger, diaphoresis,
weakness, dizziness and tachycardia
Symptoms of hyperglycemia - ANSWERSPolyuria, polydipsia and polyphagia (weight
loss)
Symptoms of DKA - ANSWERSKussmaul's respiration, ketone odor of the breath (fruity
breath), vomiting, dehydration, abdominal pain, and neurologic symptoms such as
lethargy; can progress to coma in later stages if left untreated.
Metformin - ANSWERSThis medication decreases hepatic glucose output inhibiting
gluconeogenesis. It also increases insulin mediated glucose utilization in peripheral
tissues. This medication decreases intestinal absorption of glucose. This medication
may also be used in diabetics to decrease cholesterol and triglyceride levels.
Metformin - ANSWERSWhen patients are prescribed this medication, the primary care
provider should assess serum creatinine, renal function, and creatinine clearance
initially and annually.
Gliptins (DPP4 inhibitors) - ANSWERSThese medications increase the incretin levels,
which inhibit glucagon release; this subsequently increases insulin secretion, decreases
gastric emptying and decreases blood glucose levels.
GLP-1 agonists - ANSWERSThese medications bind directly to the GLP-1 receptor,
which then slows gastric emptying and increases insulin secretion by pancreatic beta
cells.
Exenatide (Byetta) - ANSWERSThis medication should be administered 60 minutes
before breakfast and dinner.
PTU - ANSWERSAdverse effects of this medication include fatal granuloctyopenia
(presents as fever and slow throat), vasculitis, temporary alopecia, rash, aplastic
anemia, and acute renal failure.
Levothyroxine - ANSWERSAdverse effects of this medication include tachycardia and
angina, which are more noticable in the elderly.
Methimazole - ANSWERSThis medication is the recommended treatment of toxic goiter
Methimazole - ANSWERSThis medication is tetratogenic and may cause the fetus to
get aplasia acutis.
PTU - ANSWERSAdverse effects of this medication includes fatal granuloctyopenia
(presents as fever and slow throat), vasculitis, temporary alopecia, rash, aplastic
anemia, and acute renal failure.
