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Psychopharmacology Questions and
Correct Answers/ Latest Update / Already
Graded
What is the MOA of antipsychotics?
Ans: Dopamine receptor antagonists
What are the two classes of antipsychotics?
Ans: Typicals - antagonize D2 only, greater risk of side effects
Atypicals - antagonize D2, D4, and 5HTZ, favorable for long
term treatment
*Risperidone [Risperdal] - atypical, only acts on D2 and 5HTz
Typical Antipsychotic Rx
Ans: Haloperidol [Haldol], Chlorpromazine [Thorazine],
Prochlorperazine [Compazine], Fluphenazine [Prolixin]
Atypical Antipsychotic Rx
Ans: Risperidone [Risperdal]
Olanzapine [Zyprexa]
Quetiapine [Seroquel]
Clozapine [Clozaril]
All rights reserved © 2025/ 2026 |
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Ziprasidone [Geodon]
Aripiprazole [Abilify]
What are the indications for antipsychotic therapy?
Ans: 1. Psychotic disorders
2. Acute agitation - haloperidol, ziprasidone
3. Mood disorders - MDD, BP2 - adjunct to SSRI, esp.
Aripiprazole
4. Movement d/o involving excessive dopaminergic stimulation
(i.e. Huntington's, Tourette's)
Which antipsychotic is associated with agranulocytosis?
Ans: Clozapine [Clozaril]
Which antipsychotic is associated with prolongation of QT interval?
Ans: Ziprasidone [Geodon]
Which antipsychotic is the least sedating?
Ans: Risperidone [Risperdal]
All rights reserved © 2025/ 2026 |
Psychopharmacology Questions and
Correct Answers/ Latest Update / Already
Graded
What is the MOA of antipsychotics?
Ans: Dopamine receptor antagonists
What are the two classes of antipsychotics?
Ans: Typicals - antagonize D2 only, greater risk of side effects
Atypicals - antagonize D2, D4, and 5HTZ, favorable for long
term treatment
*Risperidone [Risperdal] - atypical, only acts on D2 and 5HTz
Typical Antipsychotic Rx
Ans: Haloperidol [Haldol], Chlorpromazine [Thorazine],
Prochlorperazine [Compazine], Fluphenazine [Prolixin]
Atypical Antipsychotic Rx
Ans: Risperidone [Risperdal]
Olanzapine [Zyprexa]
Quetiapine [Seroquel]
Clozapine [Clozaril]
All rights reserved © 2025/ 2026 |
, Page |2
Ziprasidone [Geodon]
Aripiprazole [Abilify]
What are the indications for antipsychotic therapy?
Ans: 1. Psychotic disorders
2. Acute agitation - haloperidol, ziprasidone
3. Mood disorders - MDD, BP2 - adjunct to SSRI, esp.
Aripiprazole
4. Movement d/o involving excessive dopaminergic stimulation
(i.e. Huntington's, Tourette's)
Which antipsychotic is associated with agranulocytosis?
Ans: Clozapine [Clozaril]
Which antipsychotic is associated with prolongation of QT interval?
Ans: Ziprasidone [Geodon]
Which antipsychotic is the least sedating?
Ans: Risperidone [Risperdal]
All rights reserved © 2025/ 2026 |
