1 | Page
WGU D027 Study Guide Questions and
Answers
Autosomal Dominant
Ans: 1 parent has, 50% change of child having
Autosomal Recessive
Ans: Both parents are carriers, 25% change of child having, 50% chance
child is a carrier.
Cystic Fibrosis
Ans: affects pancreas causing secretions in lungs
21st Trisomy
Ans: Down Syndrome
Klinefelter Syndrome (XXY)
Ans: male has extra X, female like qualities
Turner Syndrome
Ans: Missing X in females
Alpha Thalassemia
Ans: inherited blood disorder; mild to severe anemia
Beta Thallasemia
Ans: low hemoglobin; contraindicated medication ferrous sulfate
Prevalence Risk
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Ans: proportion of the population affected at a certain time
Incidence rate
Ans: number of new cases divided by population
Innate immunity
Ans: inflammation; increased vascular permeability
B&T lymphocytes
Ans: immune response
primary malignant tumor
Ans: lack of organization of cells
glucocorticoids
Ans: used in combination with other agent to treat lymphoid tissue
(leukemia). glucocorticoids are directly toxic to lymphoid tissues.
Selective estrogen receptor modulators (SERM)
Ans: for hormone receptor positive and advanced breast cancer.
(Tamoxifin reduces risk and recurrence risk)
Heart failure
Ans: impairment of the ventricle to fill with or eject blood; heart cannot
meet metabolic need of the body.
CHF
Ans: heart cannot keep up with metabolic needs; volume overload in
pulmonary area
Left Ventricular Dysfunction
Ans: reduced ejection fraction; ventricle having issue ejecting blood.
normal ejection fraction
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, 3 | Page
Ans: 55 - 60 % (blood pumped out with each heartbeat)
Ejection fraction of 50% - reduced or preserved?
Ans: preserved
Diastolic CHF
Ans: preserved ejection fraction, problem is with filling
Systolic CHF
Ans: reduced ejection fraction, problem is with ejecting
Left sided CHF
Ans: pulmonary (JVD, fluid volume overload, rails, S-3 murmurs) ** #1
cause of Right sided CHF
BNP
Ans: gold standard lab test to diagnose CHF
Echocardiogram
Ans: Diagnostic tool, evaluates heart structure and function
At Risk for HF - Stage A
Ans: no structural heart disease or symptoms of heart failure
Stage A HF co-morbidities
Ans: htn, atherosclerotic disease, diabetes, metabolic syndrome,
patients using cardiotoxins with family history
Therapy goals of stage A HF
© 2025 All rights reserved
WGU D027 Study Guide Questions and
Answers
Autosomal Dominant
Ans: 1 parent has, 50% change of child having
Autosomal Recessive
Ans: Both parents are carriers, 25% change of child having, 50% chance
child is a carrier.
Cystic Fibrosis
Ans: affects pancreas causing secretions in lungs
21st Trisomy
Ans: Down Syndrome
Klinefelter Syndrome (XXY)
Ans: male has extra X, female like qualities
Turner Syndrome
Ans: Missing X in females
Alpha Thalassemia
Ans: inherited blood disorder; mild to severe anemia
Beta Thallasemia
Ans: low hemoglobin; contraindicated medication ferrous sulfate
Prevalence Risk
© 2025 All rights reserved
, 2 | Page
Ans: proportion of the population affected at a certain time
Incidence rate
Ans: number of new cases divided by population
Innate immunity
Ans: inflammation; increased vascular permeability
B&T lymphocytes
Ans: immune response
primary malignant tumor
Ans: lack of organization of cells
glucocorticoids
Ans: used in combination with other agent to treat lymphoid tissue
(leukemia). glucocorticoids are directly toxic to lymphoid tissues.
Selective estrogen receptor modulators (SERM)
Ans: for hormone receptor positive and advanced breast cancer.
(Tamoxifin reduces risk and recurrence risk)
Heart failure
Ans: impairment of the ventricle to fill with or eject blood; heart cannot
meet metabolic need of the body.
CHF
Ans: heart cannot keep up with metabolic needs; volume overload in
pulmonary area
Left Ventricular Dysfunction
Ans: reduced ejection fraction; ventricle having issue ejecting blood.
normal ejection fraction
© 2025 All rights reserved
, 3 | Page
Ans: 55 - 60 % (blood pumped out with each heartbeat)
Ejection fraction of 50% - reduced or preserved?
Ans: preserved
Diastolic CHF
Ans: preserved ejection fraction, problem is with filling
Systolic CHF
Ans: reduced ejection fraction, problem is with ejecting
Left sided CHF
Ans: pulmonary (JVD, fluid volume overload, rails, S-3 murmurs) ** #1
cause of Right sided CHF
BNP
Ans: gold standard lab test to diagnose CHF
Echocardiogram
Ans: Diagnostic tool, evaluates heart structure and function
At Risk for HF - Stage A
Ans: no structural heart disease or symptoms of heart failure
Stage A HF co-morbidities
Ans: htn, atherosclerotic disease, diabetes, metabolic syndrome,
patients using cardiotoxins with family history
Therapy goals of stage A HF
© 2025 All rights reserved
