MH 701 EXAM 2 QUESTIONS & ANSWERS
can cause neural tube defects like spina bifida - Answer -valproic acid
can cause hepatic necrosis - Answer -valproic acid
Carbamazepine (tegretol) FDA - Answer -anticonvulsant/mood stabilizer
Carbamazepine (tegretol) Off-label - Answer -bipolar depression, bipolar maintenance,
psychosis
Carbamazepine (tegretol) 3 main clinical uses - Answer -seizures, trigeminal neuralgia,
mood stabilizer
Lamictal (lamotrigine) FDA - Answer -mood stabilizer/anticonvulsant
approved for bipolar 1 maintenance
Lamicatal (lamotrigine) off label - Answer -bipolar depression, bipolar mania (adjunct
and second line), neuropathic pain, MDD (second line)
Lamictal watch out for - Answer -Rash! Stevens Johnson Syndrome
Li 1.5-2.0 - Answer -mild to moderate toxicity- vom abd pain dry mouth ataxia slurred
speech dizziness lethargy or excitement muscle weakness
Li 2.0-2.5 - Answer -moderate to severe toxicity- anorexia N/V, blurred vision
fasciculations, clonic movements, INCR DTRs, choreoathetoid mvmnts, convulsions
delirium syncope EEG chances stupor coma circulatory failure (arrhyth low BP condxn
abn)
Li 2.5 - Answer -severe toxicity- convulsions oliguria renal failure death
Li initial labs/monitoring - Answer -baseline- serum creatinine, electrolytes, thyroid
function (TSH, T3, T4), CBC, ECG and pregnancy test.
Li continued labs/monitoring - Answer -Regular monitoring of serum lithium
concentrations is essential. Lithium levels should be obtained every 2 to 6 months
except when there are signs of toxicity, during dosage adjustments, and in persons
suspected to be noncompliant with the prescribed dosages.
Last dose of li should be approx how many hours prior to lab draw - Answer -12
valproic acid indications - Answer -acute mania in bipolar,
schizoaffecitve/schizophrenia
can cause neural tube defects like spina bifida - Answer -valproic acid
can cause hepatic necrosis - Answer -valproic acid
Carbamazepine (tegretol) FDA - Answer -anticonvulsant/mood stabilizer
Carbamazepine (tegretol) Off-label - Answer -bipolar depression, bipolar maintenance,
psychosis
Carbamazepine (tegretol) 3 main clinical uses - Answer -seizures, trigeminal neuralgia,
mood stabilizer
Lamictal (lamotrigine) FDA - Answer -mood stabilizer/anticonvulsant
approved for bipolar 1 maintenance
Lamicatal (lamotrigine) off label - Answer -bipolar depression, bipolar mania (adjunct
and second line), neuropathic pain, MDD (second line)
Lamictal watch out for - Answer -Rash! Stevens Johnson Syndrome
Li 1.5-2.0 - Answer -mild to moderate toxicity- vom abd pain dry mouth ataxia slurred
speech dizziness lethargy or excitement muscle weakness
Li 2.0-2.5 - Answer -moderate to severe toxicity- anorexia N/V, blurred vision
fasciculations, clonic movements, INCR DTRs, choreoathetoid mvmnts, convulsions
delirium syncope EEG chances stupor coma circulatory failure (arrhyth low BP condxn
abn)
Li 2.5 - Answer -severe toxicity- convulsions oliguria renal failure death
Li initial labs/monitoring - Answer -baseline- serum creatinine, electrolytes, thyroid
function (TSH, T3, T4), CBC, ECG and pregnancy test.
Li continued labs/monitoring - Answer -Regular monitoring of serum lithium
concentrations is essential. Lithium levels should be obtained every 2 to 6 months
except when there are signs of toxicity, during dosage adjustments, and in persons
suspected to be noncompliant with the prescribed dosages.
Last dose of li should be approx how many hours prior to lab draw - Answer -12
valproic acid indications - Answer -acute mania in bipolar,
schizoaffecitve/schizophrenia
