NU 665C REGIS COLLEGE EXAM QUESTIONS
AND ANSWERS LATEST 2025-2026 UPDATE
Which medication should be avoided in patients with liver disease? -
Answer-Naltrexone (can cause hepatotoxicity)
What are common screening tools for alcohol use disorder? - Answer-
AUDIT (Alcohol Use Disorders Identification Test) - Identifies
hazardous drinking
CAGE questionnaire - 4-question screening for alcohol dependence (Cut
down, Annoyed, Guilty, Eye-opener)
CIWA-Ar (Clinical Institute Withdrawal Assessment for Alcohol) -
Assesses alcohol withdrawal severity
What are common screening tools for opioid use disorder? - Answer-
ORT (Opioid Risk Tool) - Assesses risk of opioid misuse
SOAPP (Screener and Opioid Assessment for Patients with Pain) -
Evaluates risk of opioid abuse in chronic pain patients
DAST (Drug Abuse Screening Test) - General screening for drug use
disorders
What are the medication-assisted treatments (MAT) for opioid use
disorder? - Answer-Methadone - Full opioid agonist, reduces cravings
and withdrawal symptoms
Buprenorphine/Naloxone (Suboxone) - Partial agonist, reduces cravings
and withdrawal, lower overdose risk
, Naltrexone - Opioid antagonist, blocks euphoric effects, best for highly
motivated patients
Which medication is first-line for pregnant patients with opioid use
disorder? - Answer-Methadone or Buprenorphine (without naloxone)
What is precipitated withdrawal, and how does it occur? - Answer-A
rapid and severe withdrawal reaction that happens when a patient on
opioids is given naltrexone or buprenorphine too soon.
What laboratory abnormalities are common in chronic alcohol use? -
Answer-Elevated liver enzymes (AST > ALT)
Macrocytosis (MCV >100 fL) - Due to folate deficiency
Thiamine (Vitamin B1) deficiency - Risk of Wernicke-Korsakoff
syndrome
Hypoglycemia - Due to impaired gluconeogenesis
What laboratory findings are associated with opioid use disorder? -
Answer-Hypoxia - Due to respiratory depression
Elevated creatine kinase (CK) - Due to rhabdomyolysis in overdose
cases
Low testosterone levels - Common in chronic opioid use
DSM-5-TR Criteria for Substance Use Disorders (SUD)
What are the DSM-5-TR criteria for diagnosing a substance use
disorder? - Answer-The 11 criteria are grouped into 4 categories:
AND ANSWERS LATEST 2025-2026 UPDATE
Which medication should be avoided in patients with liver disease? -
Answer-Naltrexone (can cause hepatotoxicity)
What are common screening tools for alcohol use disorder? - Answer-
AUDIT (Alcohol Use Disorders Identification Test) - Identifies
hazardous drinking
CAGE questionnaire - 4-question screening for alcohol dependence (Cut
down, Annoyed, Guilty, Eye-opener)
CIWA-Ar (Clinical Institute Withdrawal Assessment for Alcohol) -
Assesses alcohol withdrawal severity
What are common screening tools for opioid use disorder? - Answer-
ORT (Opioid Risk Tool) - Assesses risk of opioid misuse
SOAPP (Screener and Opioid Assessment for Patients with Pain) -
Evaluates risk of opioid abuse in chronic pain patients
DAST (Drug Abuse Screening Test) - General screening for drug use
disorders
What are the medication-assisted treatments (MAT) for opioid use
disorder? - Answer-Methadone - Full opioid agonist, reduces cravings
and withdrawal symptoms
Buprenorphine/Naloxone (Suboxone) - Partial agonist, reduces cravings
and withdrawal, lower overdose risk
, Naltrexone - Opioid antagonist, blocks euphoric effects, best for highly
motivated patients
Which medication is first-line for pregnant patients with opioid use
disorder? - Answer-Methadone or Buprenorphine (without naloxone)
What is precipitated withdrawal, and how does it occur? - Answer-A
rapid and severe withdrawal reaction that happens when a patient on
opioids is given naltrexone or buprenorphine too soon.
What laboratory abnormalities are common in chronic alcohol use? -
Answer-Elevated liver enzymes (AST > ALT)
Macrocytosis (MCV >100 fL) - Due to folate deficiency
Thiamine (Vitamin B1) deficiency - Risk of Wernicke-Korsakoff
syndrome
Hypoglycemia - Due to impaired gluconeogenesis
What laboratory findings are associated with opioid use disorder? -
Answer-Hypoxia - Due to respiratory depression
Elevated creatine kinase (CK) - Due to rhabdomyolysis in overdose
cases
Low testosterone levels - Common in chronic opioid use
DSM-5-TR Criteria for Substance Use Disorders (SUD)
What are the DSM-5-TR criteria for diagnosing a substance use
disorder? - Answer-The 11 criteria are grouped into 4 categories:
