allergy PNCB exam questions and
answers
allergic rhinitis treatment - ANSWERS -first line: inhaled nasal corticosteriods; can take up to 4
weeks before symptom relief is observed
others: oral H1 antihistamines, leukotriene modifiers
start 1-2 weeks before pollen season
OAH--> rotate, will develop tolerance; titrate up for symptom relief
NO decongestants under age of 4 yrs
allergies - ANSWERS -allergens acts as antigen that triggers IgE responses in genetically
predisoped individuals
allergy type 1 - ANSWERS -IgE mediated
binding region of IgE attaches to high-infinity receptors on basophils, mast cells, and eosinophils
results in inflammatory mediators and cytokine release
allergy type 2 - ANSWERS -a cytotoxic reaction
IgM or IgG antibodies bind to surface antigens on normal tissue cells, activating complement
cascade, with resultant inflammation, cellular dysfunction, or toxicity
leads to cell destruction
answers
allergic rhinitis treatment - ANSWERS -first line: inhaled nasal corticosteriods; can take up to 4
weeks before symptom relief is observed
others: oral H1 antihistamines, leukotriene modifiers
start 1-2 weeks before pollen season
OAH--> rotate, will develop tolerance; titrate up for symptom relief
NO decongestants under age of 4 yrs
allergies - ANSWERS -allergens acts as antigen that triggers IgE responses in genetically
predisoped individuals
allergy type 1 - ANSWERS -IgE mediated
binding region of IgE attaches to high-infinity receptors on basophils, mast cells, and eosinophils
results in inflammatory mediators and cytokine release
allergy type 2 - ANSWERS -a cytotoxic reaction
IgM or IgG antibodies bind to surface antigens on normal tissue cells, activating complement
cascade, with resultant inflammation, cellular dysfunction, or toxicity
leads to cell destruction
