TEST BANK
Lippincott Illustrated Reviews: Pharmacology
KAREN WHALEN
Eighth, North American Edition
,Pharmacology Illustrated Reviews 8th Edition Whalen Test Bank
Chapter 1: Pharmacokinetics
MULTIPLE CHOICE
1. Which drugs will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral analgesics
d. Subcutaneous
antiglycemics ANS:C
When drugs are administered parenterally, there is no pharmaceutic phase, which occurs when a
drug becomes a solution that can cross the biologic membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSIN"G PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological andParenteral Therapies
2. The nurse is preparing to administer an oral medication and wants to ensure a rapid
drug action. Which form of the medication will the nurse administer?
a. Capsule
b. Enteric-coated pill
c. Liquid suspension
d. Tablet
ANS:C
Liquid drugs are already in solution, which is the form necessary for absorption in the GI
tract. The other forms must disintegrate into small particles and then dis solve before being
absorbed.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSIN"G PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 1 of 507
,3. The nurse is teaching a patient who will be discharged home with a prescription for an
enteric- coated tablet. Which statement by the patient indicates understanding of the
teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its
action. ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of
actions after taking these medications. Enteric-coated tablets should not be crushed or
chewed, which would alter the time and location of absorption. Acidic foods will not enhance
the absorption of the medication. The patient should not to eat high-fat food before
ingesting an enteric-coated tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP:
NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must
be given by subcutaneous injection instead of by mouth. The nurse will explain that this is
because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse
effects. ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small
intestine by digestive enzymes and must be given parenterally. Because insulin is
destroyed by digestive enzymes, it would not make it to the liver for metabolism with a
first-pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in
such tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 2 of 507
, 5. The nurse is preparing to administer an oral medication that is water-soluble. The
nurse understands that this drug
a. must be taken on an empty stomach.
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal
tract. ANS: B
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
6. A nurse is preparing to administer an oral drug that is best absorbed in an acidic
environment. How will the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food
ANS: C
Food can stimulate the production of gastric acid so medications requiring an acidic
environment should be given with a meal. High-fat foods are useful for drugs that are lipid
soluble.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4 TOP:
NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
7. The nurse is preparing an injectable drug and wants to administer it for rapid absorption.
How will the nurse give this medication?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper
arm ANS: A
Page 3 of 507
Lippincott Illustrated Reviews: Pharmacology
KAREN WHALEN
Eighth, North American Edition
,Pharmacology Illustrated Reviews 8th Edition Whalen Test Bank
Chapter 1: Pharmacokinetics
MULTIPLE CHOICE
1. Which drugs will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral analgesics
d. Subcutaneous
antiglycemics ANS:C
When drugs are administered parenterally, there is no pharmaceutic phase, which occurs when a
drug becomes a solution that can cross the biologic membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSIN"G PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological andParenteral Therapies
2. The nurse is preparing to administer an oral medication and wants to ensure a rapid
drug action. Which form of the medication will the nurse administer?
a. Capsule
b. Enteric-coated pill
c. Liquid suspension
d. Tablet
ANS:C
Liquid drugs are already in solution, which is the form necessary for absorption in the GI
tract. The other forms must disintegrate into small particles and then dis solve before being
absorbed.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSIN"G PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 1 of 507
,3. The nurse is teaching a patient who will be discharged home with a prescription for an
enteric- coated tablet. Which statement by the patient indicates understanding of the
teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its
action. ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of
actions after taking these medications. Enteric-coated tablets should not be crushed or
chewed, which would alter the time and location of absorption. Acidic foods will not enhance
the absorption of the medication. The patient should not to eat high-fat food before
ingesting an enteric-coated tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP:
NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must
be given by subcutaneous injection instead of by mouth. The nurse will explain that this is
because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse
effects. ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small
intestine by digestive enzymes and must be given parenterally. Because insulin is
destroyed by digestive enzymes, it would not make it to the liver for metabolism with a
first-pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in
such tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 2 of 507
, 5. The nurse is preparing to administer an oral medication that is water-soluble. The
nurse understands that this drug
a. must be taken on an empty stomach.
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal
tract. ANS: B
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
6. A nurse is preparing to administer an oral drug that is best absorbed in an acidic
environment. How will the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food
ANS: C
Food can stimulate the production of gastric acid so medications requiring an acidic
environment should be given with a meal. High-fat foods are useful for drugs that are lipid
soluble.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4 TOP:
NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
7. The nurse is preparing an injectable drug and wants to administer it for rapid absorption.
How will the nurse give this medication?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper
arm ANS: A
Page 3 of 507
