APhA Immunization Exam Questions and
Answers 2025-2026
What is the minimum needle length recommended for administering HepB
vaccine to an adult patient weighing 130 lb? Correct Answer Fixed 1-inch
needles are acceptable for patients weighing 60 kg (132 lb) or less.
HZV, MMR, rabies, typhoid, varicella, or yellow fever vaccine should not be
administered to a patient with a history of anaphylaxis to: Correct Answer
Gelatin
Alan is a 47-year-old man who has no documentation of a primary series of
tetanus-containing vaccine. Which of the following would be an appropriate
primary series for Alan? Correct Answer 1) Tdap
2) Td 4 weeks later
3) Td 6-12 months later
Td booster every 10 years after 3rd dose
Candidate for PPSV23? Correct Answer All adults 65+ years
Immunocompromised (alcoholism, chronic liver; heart; lung disease,
diabetics, cochlear implants, CSF leak) patients ages 19-64
Children with asthma only if theyre treated with high dose corticosteriods
Name the vaccine-preventable disease that may be contracted by
unimmunized children from adults serving as reservoirs for the disease,
which causes a paroxysmal cough and potentially can result in pneumonia,
seizures, encephalopathy, hypoxia, and death. Correct Answer Pertussis
,APhA Immunization Exam Questions and
Answers 2025-2026
Which of the following vaccines may be administered to males and females
aged 9 through 26 years to reduce the likelihood of acquiring genital warts?
Correct Answer 9vHPV
Which of the following key questions is important to ask a patient before
administering IIV? Correct Answer Are you sick today?
*Mild illness is okay, but moderate to severe acute illness need to be
resolved before getting vaccine.
Live attenuated vaccines.. Correct Answer produced by weakening the
virus or bacteria to reduce the likelihood that it can cause disease
end to produce more persistent, longer-lasting immunity than inactivated
vaccines
must replicate in order for the body to produce an immune response
could cause disease in immunocompromised patients
Circulating antibodies may interfere with a live attenuated vaccine's ability to
replicate.
Inactivated vaccines... Correct Answer are produced by killing the
virus/bacteria
includes polysaccharide vaccines (conjugated [protein altered] or
unconjugated), toxoids, or cellular vaccines
, APhA Immunization Exam Questions and
Answers 2025-2026
Which type of vaccine involves stimulation of B cells without the assistance
of T helper cells? Correct Answer A pure polysaccharide
*not recommended for children <2 because of their immature immune
system
Conjugated vaccines.. Correct Answer provide longer lasting protection
the immune response that changes to a T cell mediated response allows
children <2 to form an immune response
T/F
Both live attenuated vaccines and recombinant vaccines mimic natural
infection and involve T cells in the immune response. Correct Answer True
The incubation period for influenza can range from: Correct Answer 1-4
days
What is the time interval for which the development of Guillain-Barré
syndrome following influenza vaccination would result in a precaution for
future influenza vaccines? Correct Answer 6 weeks
The monitoring system that health care providers should use to report
serious adverse events after vaccination is: Correct Answer VAERS
Which of the following patients are appropriate candidates for the 2-dose
schedule of HPV9? Correct Answer 11 or 12 year olds
Answers 2025-2026
What is the minimum needle length recommended for administering HepB
vaccine to an adult patient weighing 130 lb? Correct Answer Fixed 1-inch
needles are acceptable for patients weighing 60 kg (132 lb) or less.
HZV, MMR, rabies, typhoid, varicella, or yellow fever vaccine should not be
administered to a patient with a history of anaphylaxis to: Correct Answer
Gelatin
Alan is a 47-year-old man who has no documentation of a primary series of
tetanus-containing vaccine. Which of the following would be an appropriate
primary series for Alan? Correct Answer 1) Tdap
2) Td 4 weeks later
3) Td 6-12 months later
Td booster every 10 years after 3rd dose
Candidate for PPSV23? Correct Answer All adults 65+ years
Immunocompromised (alcoholism, chronic liver; heart; lung disease,
diabetics, cochlear implants, CSF leak) patients ages 19-64
Children with asthma only if theyre treated with high dose corticosteriods
Name the vaccine-preventable disease that may be contracted by
unimmunized children from adults serving as reservoirs for the disease,
which causes a paroxysmal cough and potentially can result in pneumonia,
seizures, encephalopathy, hypoxia, and death. Correct Answer Pertussis
,APhA Immunization Exam Questions and
Answers 2025-2026
Which of the following vaccines may be administered to males and females
aged 9 through 26 years to reduce the likelihood of acquiring genital warts?
Correct Answer 9vHPV
Which of the following key questions is important to ask a patient before
administering IIV? Correct Answer Are you sick today?
*Mild illness is okay, but moderate to severe acute illness need to be
resolved before getting vaccine.
Live attenuated vaccines.. Correct Answer produced by weakening the
virus or bacteria to reduce the likelihood that it can cause disease
end to produce more persistent, longer-lasting immunity than inactivated
vaccines
must replicate in order for the body to produce an immune response
could cause disease in immunocompromised patients
Circulating antibodies may interfere with a live attenuated vaccine's ability to
replicate.
Inactivated vaccines... Correct Answer are produced by killing the
virus/bacteria
includes polysaccharide vaccines (conjugated [protein altered] or
unconjugated), toxoids, or cellular vaccines
, APhA Immunization Exam Questions and
Answers 2025-2026
Which type of vaccine involves stimulation of B cells without the assistance
of T helper cells? Correct Answer A pure polysaccharide
*not recommended for children <2 because of their immature immune
system
Conjugated vaccines.. Correct Answer provide longer lasting protection
the immune response that changes to a T cell mediated response allows
children <2 to form an immune response
T/F
Both live attenuated vaccines and recombinant vaccines mimic natural
infection and involve T cells in the immune response. Correct Answer True
The incubation period for influenza can range from: Correct Answer 1-4
days
What is the time interval for which the development of Guillain-Barré
syndrome following influenza vaccination would result in a precaution for
future influenza vaccines? Correct Answer 6 weeks
The monitoring system that health care providers should use to report
serious adverse events after vaccination is: Correct Answer VAERS
Which of the following patients are appropriate candidates for the 2-dose
schedule of HPV9? Correct Answer 11 or 12 year olds
