N136 MCA2 – Hematology Questions With Complete
Solutions
Y/N to whether the following etiologies are related to
Cobalamin deficiency:
1. GI surgery
2. Crohn's/Celiac disease
3. Long term use of PPR's or H2 blockers
4. Alcohol use
5. Poor diet
6. Pernicious anemia
All of the options are etiologies of cobalamin deficiency.
What are the signs and symptoms of cobalamin deficiency?
General anemia signs, sore/red/beefy tongue, anorexia, nausea,
vomiting and abdominal pain, weakness, parasthesia, confusion,
severe memory loss
Pernicious anemia is the lack of _________ caused by
________________.
Lack of mature erythrocytes caused by inability to absorb
vitamin B12 into the bloodstream
Lab work for cobalamin deficiency includes CBC, Vit B12
levels, and a Schilling test - what is a Schilling test?
Schilling test measures cobalamin absorption levels (also note
that multiple sources say the Schilling test is no longer used)
, Nursing management for cobalamin deficiency involves
supplementation, and dietary intake - what types of
supplementation options are available?
Oral, parenteral, or intranasal replacement. IM replacement is
(usually) 1000 mcg/day x2 weeks, then weekly after that.
Cobalamin deficiency can lead to death without supplementation
- how many years, approximately, will that take?
1-3 years without supplementation
Folic acid (B9) deficiency anemia is defined as
inability to produce sufficient red blood cells due to the lack of
folic acid, a B vitamin essential for erythropoiesis
The etiology of folic acid deficiency includes poor nutrition,
malabsorption, alcohol use, and drug use - what are the clinical
manifestations?
General symptoms of anemia, smooth/beefy tongue, prone to
mouth sores
Diagnostic tests to diagnose folic acid deficiency are folic acid
levels and CBC - how should the nurse educate the patient after
diagnosis?
Dietary and oral replacement - green leafy vegetables, orange
juice, peanuts, avocado
Sickle cell anemia is defined as
Genetic disorder of abnormal hemoglobin producing sickle-
shaped erythrocytes and hemolysis, making S-shaped clumps in
the capillaries.
Solutions
Y/N to whether the following etiologies are related to
Cobalamin deficiency:
1. GI surgery
2. Crohn's/Celiac disease
3. Long term use of PPR's or H2 blockers
4. Alcohol use
5. Poor diet
6. Pernicious anemia
All of the options are etiologies of cobalamin deficiency.
What are the signs and symptoms of cobalamin deficiency?
General anemia signs, sore/red/beefy tongue, anorexia, nausea,
vomiting and abdominal pain, weakness, parasthesia, confusion,
severe memory loss
Pernicious anemia is the lack of _________ caused by
________________.
Lack of mature erythrocytes caused by inability to absorb
vitamin B12 into the bloodstream
Lab work for cobalamin deficiency includes CBC, Vit B12
levels, and a Schilling test - what is a Schilling test?
Schilling test measures cobalamin absorption levels (also note
that multiple sources say the Schilling test is no longer used)
, Nursing management for cobalamin deficiency involves
supplementation, and dietary intake - what types of
supplementation options are available?
Oral, parenteral, or intranasal replacement. IM replacement is
(usually) 1000 mcg/day x2 weeks, then weekly after that.
Cobalamin deficiency can lead to death without supplementation
- how many years, approximately, will that take?
1-3 years without supplementation
Folic acid (B9) deficiency anemia is defined as
inability to produce sufficient red blood cells due to the lack of
folic acid, a B vitamin essential for erythropoiesis
The etiology of folic acid deficiency includes poor nutrition,
malabsorption, alcohol use, and drug use - what are the clinical
manifestations?
General symptoms of anemia, smooth/beefy tongue, prone to
mouth sores
Diagnostic tests to diagnose folic acid deficiency are folic acid
levels and CBC - how should the nurse educate the patient after
diagnosis?
Dietary and oral replacement - green leafy vegetables, orange
juice, peanuts, avocado
Sickle cell anemia is defined as
Genetic disorder of abnormal hemoglobin producing sickle-
shaped erythrocytes and hemolysis, making S-shaped clumps in
the capillaries.
