a drug is moved from the site of administration to body fluids; first process during
pharmacokinetics - Answers absorption
undesirable drug effect - Answers adverse reaction
hypersensitive reaction by the immune system; it presents as itching, hives, swelling, and
difficulty breathing - Answers Allergic reaction
sudden, severe hypersensitivity reaction with symptoms that progress rapidly and may result in
death if not treated; also called anaphylactic reaction or anaphylactoid reaction (allergic reaction)
- Answers Anaphylactic shock
localized wheals or swellings of liquid in subcutaneous tissues or mucous membranes, which
may be caused by an allergic reaction ; also called angioneurotic edema. Most common in
eyelids, lips, mouth, and throat. - Answers Angioedema
the proportion of a drug available to body tissues when it reaches the circulatory system -
Answers bioavailability
drugs that have the potential for abuse and dependency, both physical and psychological -
Answers controlled substances
when the body is unable to metabolize and excrete one dose of a drug before the next is given -
Answers Cumulative drug effect
group of diverse medical practices or products not presently part of conventional medicine -
Answers Complementary/Alternative Medicine (CAM)
drug moves from circulation to body tissue or a target site - Answers distribution
any unusual or abnormal response that differs from the response normally expected to a
specific drug and dosage. - Answers drug idiosyncrasy
decreased response to a drug, requiring an increase in dosage to achieve the desired effect -
Answers drug tolerance
elimination of a drug from the body - Answers excretion
action by which an oral drug is absorbed and carried directly to the liver, where it is inactivated
by enzymes before it enters the general bloodstream - Answers first pass effect
time required for the body to eliminate 50% of a drug - Answers Half life
type of complementary/alternative therapy that uses plants or herbs to treat vanous disorders;
aiso called herbalism - Answers Herbal medicine
, undesirable reaction produced by a normal immune system - Answers hypersensitive
drug is changed to a form that can be excreted - Answers metabolism
inactive form of the original drug - Answers metabolite
drugs designated by the US Food and Drug Administration (FDA) to be safe (if taken as directed)
and obtainable without a prescription; also called over-the-counter (OTC) drugs - Answers
Nonprescription Drugs
pertaining to the phase during which a drug dissolves in the body - Answers pharmaceutic
study of the drug mechanisms that produce biochemical or physiologic changes in the body -
Answers Pharmacodynamics
study of drug transit (or activity) after administration - Answers Pharmacokinetics
habitual use of a drug, where negative physical withdrawal symptoms result from abrupt
discontinuation - Answers physical dependency
drugs the federal government has designated Order as potentially harmful unless their use is
supervised by a licensed health care provider, such as a nurse practitioner, physician, or dentist -
Answers Prescription drugs
compulsion or craving to use a substance to obtain a pleasurable experience - Answers
psychological dependency
Cellular macromolecule to which medication binds in order to initiate its effects, a reactive site
on the surface of a cell; when a drug binds to and interacts with the receptor, a pharmacologic
response occurs - Answers Receptor
program of the FDA, designed to monitor drugs that have a high risk compared with benefit ratio
- Answers Risk Evaluation and Mitigation Strategies (REMS)
drug or substance that causes abnormal development of the fetus, leading to deformities or
death - Answers teratogen
poisonous or harmful - Answers toxic
mouth cavity between jaw and cheek - Answers buccal
entry by way of the gastrointestinal system - Answers enteral
drug administration route in which the client inhales the drug orally or nasally - Answers
inhalation
pertaining to the dermis area within the upper layers of the skin - Answers intradermal