Test Bank
For Pathophysiology | The
Biologic Basis for Disease
in Adults and Children
8th Edition | Latest
Version 2024
,Chapter1q11q-1 q Cellular1qBiology ______________________________________ 3
Chapter1q21q-1qAltered1qCellular1qand1qTissue1qBiology1 q Environmental1qAgents ___ 16
Chapter1q31q-1qThe1qCellular1qEnvironment1qFluids1qand1qElectrolytes1qAcids1 q and
Bases _________________________________________________________ 28
Chapter1q41q-1qGenes1qand1 q Genetic1qDiseases __________________________ 41
Chapter1q51q-1qGenes1qEnvironment-Lifestyle1qand1 q Common1qDiseases _______ 51
Chapter1q61q-1qEpigenetics1 q and1qDisease _______________________________ 59
Chapter1q71q-1qInnate1 q Immunity1qInflammation ___________________________ 64
Chapter1q81q-1 q Adaptive1qImmunity ____________________________________ 78
Chapter1q91q-1qAlterations1qin1qImmunity1 q and1qInflammation _________________ 89
Chapter1q101q-1qInfection____________________________________________ 102
Chapter1q111q-1qStress1 q and1qDisease __________________________________ 110
Chapter1q121q-1 q Cancer1qBiology ______________________________________ 117
Chapter1q131q-1 q Cancer1qEpidemiology _________________________________ 129
Chapter1q141q-1qCancer1 q in1qChildren __________________________________ 135
Chapter1q151q-1qStructure1qand1qFunction1qof1qthe1 q Neurologic1qSystem _________ 140
Chapter1 q 161 q -
1 q Pain1 q Temperature1 q Regulation1 q Sleep1 q and1 q Sensory1 q Function1 q 1511qChapter1
q 171q-1qAlterations1qin1qCognitive1qSystems1qCerebral1qHemodynamics1 q and
Motor1qFunction __________________________________________________ 165
Chapter1q181q-1qDisorders1qof1qthe1qCentral1qand1qPeripheral1qNervous1qSystems1 q and
the1qNeuromuscular1qJunction _______________________________________ 179
Chapter1q191q-
1q Neurobiology1qof1qSchizophrenia1qMood1qDisorders1qand1qAnxiety1qDisorders __ 189
Chapter1q201q-1qAlterations1qof1qNeurologic1qFunction1 q in1qChildren ____________ 195
Chapter1q211q-1qMechanisms1qof1 q Hormonal1qRegulation ___________________ 202
Chapter1q221q-1qAlterations1qof1 q Hormonal1qRegulation _____________________ 211
Chapter1q231q-1qObesity1qand1qDisorders1qof1 q Nutrition1qNEW ________________ 223
Chapter1q241q-1qStructure1qand1qFunction1qof1qthe1 q Reproductive1qSystems ______ 228
Chapter1q251q-1qAlterations1qof1qthe1qFemale1 q Reproductive1qSystem __________ 237
,Chapter1q261q-1qAlterations1qof1qthe1qMale1 q Reproductive1qSystem ____________ 246
Chapter1q271q-1qSexually1 q Transmitted1qInfections ________________________ 252
Chapter1q281q-1qStructure1qand1qFunction1qof1qthe1 q Hematologic1qSystem _______ 260
Chapter1q291q-1qAlterations1qof1qErythrocyte1qPlatelet1qand1 q Hemostatic1qFunction 270
Chapter1q301q-1qAlterations1qof1qLeukocyte1qand1 q Lymphoid1qFunction__________ 280
Chapter1q311q-1qAlterations1qof1qHematologic1qFunction1 q in1qChildren __________ 287
Chapter1q321q-
1q Structure1qand1qFunction1qof1qthe1qCardiovascular1qand1qLymphatic1 q Systems __ 297
Chapter1q331q-1qAlterations1qof1 q Cardiovascular1qFunction __________________ 309
Chapter1q341q-1qAlterations1qof1qCardiovascular1qFunction1 q in1qChildren_________ 323
Chapter1q351q-1qStructure1qand1qFunction1qof1qthe1 q Pulmonary1qSystem _________ 331
Chapter1q361q-1qAlterations1qof1 q Pulmonary1qFunction ______________________ 341
Chapter1q371q-1qAlterations1qof1qPulmonary1qFunction1 q in1qChildren ____________ 357
Chapter1q381q-1qStructure1qand1qFunction1qof1qthe1qRenal1qand1 q Urologic1qSystems 365
Chapter1q391q-1qAlterations1qof1qRenal1qand1 q Urinary1qFunction _______________ 375
Chapter1q401q-1qAlterations1qof1qRenal1qand1qUrinary1qTract1qFunction1 q in1qChildren 385
Chapter1q411q-1qStructure1qand1qFunction1qof1qthe1 q Digestive1qSystem __________ 393
Chapter1q421q-1qAlterations1qof1 q Digestive1qFunction _______________________ 404
Chapter1q431q-1qAlterations1qof1qDigestive1qFunction1 q in1qChildren _____________ 415
Chapter1q441q-1qStructure1qand1qFunction1qof1qthe1 q Musculoskeletal1qSystem _____ 424
Chapter1q451q-1qAlterations1qof1 q Musculoskeletal1qFunction __________________ 436
Chapter1q461q-1qAlterations1qof1qMusculoskeletal1qFunction1 q in1qChildren ________ 448
Chapter1q471q-1qStructure1qFunction1qand1qDisorders1qof1 q the1qIntegument_______ 457
Chapter1q481q-1qAlterations1qof1qthe1qIntegument1 q in1qChildren ________________ 468
Chapter1q491q-1qShock1qMultiple1qOrgan1qDysfunction1qSyndrome1qand1qBurns1 q in
Adults _________________________________________________________ 476
Chapter1q501q-1qShock1qMultiple1qOrgan1qDysfunction1qSyndrome1qand1qBurns1 q in
Children ________________________________________________________ 483
, Chapter1q01:1qCellular1qBiology
McCance/Huether:1qPathophysiology:1qThe1qBiologic1qBasis1qof1qDisease1qin1qAdults1qan
d1qChildren,1q8th1qEdition
MULTIPLE1qCHOICE
1. Which1qstatement1qbest1qdescribes1qthe1qcellular1qfunction1qof1qmetabolic1qabsorption?
a. Cells1qcan1qproduce1qproteins.
b. Cells1qcan1qsecrete1qdigestive1qenzymes.
c. Cells1qcan1qtake1qin1qand1quse1qnutrients.
d. Cells1qcan1qsynthesize1qfats.
ANS:1 q C
In1qmetabolic1qabsorption,1qall1qcells1qtake1qin1qand1quse1qnutrients1qand1qother1qsubstances1qfro
m1qtheir1qsurroundings.1qThe1qremaining1qoptions1qare1qnot1qinclusive1qin1qtheir1qdescriptions1q
of1qcellular1qmetabolic1qabsorption.
PTS:1 q 1 q 1 DIF: Cognitive1qLevel:1qRemembering
2. Where1qis1qmost1qof1qa1qcell’s1qgenetic1qinformation,1qincluding1qRNA1qand1qDNA,1qcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:1 q C
The1qnucleus1qcontains1qthe1qnucleolus,1qa1qsmall1qdense1qstructure1qcomposed1qlargely1qof1qRNA,
1qmost1qof1qthe1qcellular1qDNA,1qand1qthe1qDNA-
binding1qproteins,1qsuch1qas1qthe1qhistones,1qwhich1qregulate1qits1qactivity.1qThe1qmitochondria1qar
e1qresponsible1qfor1qcellular1qrespiration1qand1qenergy1qproduction.
Ribosomes’1qchief1qfunction1qis1qto1qprovide1qsites1qfor1qcellular1qprotein1qsynthesis.1qLysosom
es1qfunction1qas1qthe1qintracellular1qdigestive1qsystem.
PTS:1 q 1 q 1 DIF: Cognitive1qLevel:1qRemembering
3. Which1qcomponent1qof1qthe1qcell1qproduces1qhydrogen1qperoxide1q(H2O2)1qby1qusing1qoxygen1qto1q
remove1qhydrogen1qatoms1qfrom1qspecific1qsubstrates1qin1qan1qoxidative1qreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:1 q B
For Pathophysiology | The
Biologic Basis for Disease
in Adults and Children
8th Edition | Latest
Version 2024
,Chapter1q11q-1 q Cellular1qBiology ______________________________________ 3
Chapter1q21q-1qAltered1qCellular1qand1qTissue1qBiology1 q Environmental1qAgents ___ 16
Chapter1q31q-1qThe1qCellular1qEnvironment1qFluids1qand1qElectrolytes1qAcids1 q and
Bases _________________________________________________________ 28
Chapter1q41q-1qGenes1qand1 q Genetic1qDiseases __________________________ 41
Chapter1q51q-1qGenes1qEnvironment-Lifestyle1qand1 q Common1qDiseases _______ 51
Chapter1q61q-1qEpigenetics1 q and1qDisease _______________________________ 59
Chapter1q71q-1qInnate1 q Immunity1qInflammation ___________________________ 64
Chapter1q81q-1 q Adaptive1qImmunity ____________________________________ 78
Chapter1q91q-1qAlterations1qin1qImmunity1 q and1qInflammation _________________ 89
Chapter1q101q-1qInfection____________________________________________ 102
Chapter1q111q-1qStress1 q and1qDisease __________________________________ 110
Chapter1q121q-1 q Cancer1qBiology ______________________________________ 117
Chapter1q131q-1 q Cancer1qEpidemiology _________________________________ 129
Chapter1q141q-1qCancer1 q in1qChildren __________________________________ 135
Chapter1q151q-1qStructure1qand1qFunction1qof1qthe1 q Neurologic1qSystem _________ 140
Chapter1 q 161 q -
1 q Pain1 q Temperature1 q Regulation1 q Sleep1 q and1 q Sensory1 q Function1 q 1511qChapter1
q 171q-1qAlterations1qin1qCognitive1qSystems1qCerebral1qHemodynamics1 q and
Motor1qFunction __________________________________________________ 165
Chapter1q181q-1qDisorders1qof1qthe1qCentral1qand1qPeripheral1qNervous1qSystems1 q and
the1qNeuromuscular1qJunction _______________________________________ 179
Chapter1q191q-
1q Neurobiology1qof1qSchizophrenia1qMood1qDisorders1qand1qAnxiety1qDisorders __ 189
Chapter1q201q-1qAlterations1qof1qNeurologic1qFunction1 q in1qChildren ____________ 195
Chapter1q211q-1qMechanisms1qof1 q Hormonal1qRegulation ___________________ 202
Chapter1q221q-1qAlterations1qof1 q Hormonal1qRegulation _____________________ 211
Chapter1q231q-1qObesity1qand1qDisorders1qof1 q Nutrition1qNEW ________________ 223
Chapter1q241q-1qStructure1qand1qFunction1qof1qthe1 q Reproductive1qSystems ______ 228
Chapter1q251q-1qAlterations1qof1qthe1qFemale1 q Reproductive1qSystem __________ 237
,Chapter1q261q-1qAlterations1qof1qthe1qMale1 q Reproductive1qSystem ____________ 246
Chapter1q271q-1qSexually1 q Transmitted1qInfections ________________________ 252
Chapter1q281q-1qStructure1qand1qFunction1qof1qthe1 q Hematologic1qSystem _______ 260
Chapter1q291q-1qAlterations1qof1qErythrocyte1qPlatelet1qand1 q Hemostatic1qFunction 270
Chapter1q301q-1qAlterations1qof1qLeukocyte1qand1 q Lymphoid1qFunction__________ 280
Chapter1q311q-1qAlterations1qof1qHematologic1qFunction1 q in1qChildren __________ 287
Chapter1q321q-
1q Structure1qand1qFunction1qof1qthe1qCardiovascular1qand1qLymphatic1 q Systems __ 297
Chapter1q331q-1qAlterations1qof1 q Cardiovascular1qFunction __________________ 309
Chapter1q341q-1qAlterations1qof1qCardiovascular1qFunction1 q in1qChildren_________ 323
Chapter1q351q-1qStructure1qand1qFunction1qof1qthe1 q Pulmonary1qSystem _________ 331
Chapter1q361q-1qAlterations1qof1 q Pulmonary1qFunction ______________________ 341
Chapter1q371q-1qAlterations1qof1qPulmonary1qFunction1 q in1qChildren ____________ 357
Chapter1q381q-1qStructure1qand1qFunction1qof1qthe1qRenal1qand1 q Urologic1qSystems 365
Chapter1q391q-1qAlterations1qof1qRenal1qand1 q Urinary1qFunction _______________ 375
Chapter1q401q-1qAlterations1qof1qRenal1qand1qUrinary1qTract1qFunction1 q in1qChildren 385
Chapter1q411q-1qStructure1qand1qFunction1qof1qthe1 q Digestive1qSystem __________ 393
Chapter1q421q-1qAlterations1qof1 q Digestive1qFunction _______________________ 404
Chapter1q431q-1qAlterations1qof1qDigestive1qFunction1 q in1qChildren _____________ 415
Chapter1q441q-1qStructure1qand1qFunction1qof1qthe1 q Musculoskeletal1qSystem _____ 424
Chapter1q451q-1qAlterations1qof1 q Musculoskeletal1qFunction __________________ 436
Chapter1q461q-1qAlterations1qof1qMusculoskeletal1qFunction1 q in1qChildren ________ 448
Chapter1q471q-1qStructure1qFunction1qand1qDisorders1qof1 q the1qIntegument_______ 457
Chapter1q481q-1qAlterations1qof1qthe1qIntegument1 q in1qChildren ________________ 468
Chapter1q491q-1qShock1qMultiple1qOrgan1qDysfunction1qSyndrome1qand1qBurns1 q in
Adults _________________________________________________________ 476
Chapter1q501q-1qShock1qMultiple1qOrgan1qDysfunction1qSyndrome1qand1qBurns1 q in
Children ________________________________________________________ 483
, Chapter1q01:1qCellular1qBiology
McCance/Huether:1qPathophysiology:1qThe1qBiologic1qBasis1qof1qDisease1qin1qAdults1qan
d1qChildren,1q8th1qEdition
MULTIPLE1qCHOICE
1. Which1qstatement1qbest1qdescribes1qthe1qcellular1qfunction1qof1qmetabolic1qabsorption?
a. Cells1qcan1qproduce1qproteins.
b. Cells1qcan1qsecrete1qdigestive1qenzymes.
c. Cells1qcan1qtake1qin1qand1quse1qnutrients.
d. Cells1qcan1qsynthesize1qfats.
ANS:1 q C
In1qmetabolic1qabsorption,1qall1qcells1qtake1qin1qand1quse1qnutrients1qand1qother1qsubstances1qfro
m1qtheir1qsurroundings.1qThe1qremaining1qoptions1qare1qnot1qinclusive1qin1qtheir1qdescriptions1q
of1qcellular1qmetabolic1qabsorption.
PTS:1 q 1 q 1 DIF: Cognitive1qLevel:1qRemembering
2. Where1qis1qmost1qof1qa1qcell’s1qgenetic1qinformation,1qincluding1qRNA1qand1qDNA,1qcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:1 q C
The1qnucleus1qcontains1qthe1qnucleolus,1qa1qsmall1qdense1qstructure1qcomposed1qlargely1qof1qRNA,
1qmost1qof1qthe1qcellular1qDNA,1qand1qthe1qDNA-
binding1qproteins,1qsuch1qas1qthe1qhistones,1qwhich1qregulate1qits1qactivity.1qThe1qmitochondria1qar
e1qresponsible1qfor1qcellular1qrespiration1qand1qenergy1qproduction.
Ribosomes’1qchief1qfunction1qis1qto1qprovide1qsites1qfor1qcellular1qprotein1qsynthesis.1qLysosom
es1qfunction1qas1qthe1qintracellular1qdigestive1qsystem.
PTS:1 q 1 q 1 DIF: Cognitive1qLevel:1qRemembering
3. Which1qcomponent1qof1qthe1qcell1qproduces1qhydrogen1qperoxide1q(H2O2)1qby1qusing1qoxygen1qto1q
remove1qhydrogen1qatoms1qfrom1qspecific1qsubstrates1qin1qan1qoxidative1qreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:1 q B
