NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Paroxetine - (answer)An SSRI that may cause erectile dysfunction.
Ethosuximide Monitoring - (answer)Patients should be monitored for blood dyscrasias which are
uncommon but possible.
Lamotrigine and OCPs Interaction - (answer)OCPs can reduce lamotrigine levels, requiring an increase in
the dose of lamotrigine.
Tricyclic Antidepressants Caution - (answer)Should be prescribed cautiously in patients with CAD.
Onset of Action Symptoms for SSRIs - (answer)Patients may feel a bit of nausea, which resolves in about
1 week.
Pediatric Dosing Information - (answer)There is a lack of evidence-based literature on the safe and
effective use of medications in children.
Neonates and Protein-Bound Drugs - (answer)Protein binding is decreased in neonates, increasing the
amount of free drug available.
Adult Renal Function Age - (answer)Adult levels of renal function are achieved at 12 months.
Beers List - (answer)A list that identifies drugs with a high likelihood of causing adverse effects in the
elderly.
Gastric Acidity in Pediatric Patients - (answer)Gastric acidity does not reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - (answer)Include altered pharmacokinetics, multiple and
severe illnesses, multiple-drug therapy, and poor adherence.
,NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Altered Absorption in the Elderly - (answer)May result in a delay in drug response.
Factors Altering Drug Distribution in the Elderly - (answer)Include increased body fat, decreased
percentage of lean body mass, decreased total body water, and reduced concentration of serum
albumin.
Adverse Drug Reactions in the Elderly - (answer)The most important cause of adverse drug reactions in
the elderly is polypharmacy.
Bupropion - (answer)An alternative medication that can be added to help with erectile dysfunction
caused by SSRIs.
Increased Seizure Activity with Ethosuximide - (answer)Ethosuximide can induce seizures, so increased
seizure activity should be monitored.
Renal Dysfunction Monitoring - (answer)Patients on ethosuximide should be monitored for renal
dysfunction.
Weight Gain with OCPs - (answer)OCPs can cause weight gain, which may be a concern for patients
taking lamotrigine.
Hepatotoxicity with Ethosuximide - (answer)Hepatotoxicity is a potential risk, but uncommon.
Contraceptive Failure with OCPs - (answer)OCPs may lead to contraceptive failure when interacting with
lamotrigine.
Insomnia with SSRIs - (answer)Patients may experience insomnia for a week after starting SSRIs.
FDA and Pediatric Dosing - (answer)The FDA does not require pediatric dosing information for all
medications.
,NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Free Drug Availability in Neonates - (answer)Decreased protein binding in neonates increases the
amount of free drug available.
Proper index of renal function in the elderly - (answer)Creatinine clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population - (answer)Polypharmacy, severe
illness, multiple pathologies, greater use of drugs that have a low therapeutic index, inadequate
supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - (answer)200 mg.
Properties determining anesthetic penetration of axon membrane - (answer)Molecular size, lipid
solubility, degree of ionization at tissue pH.
Medication that will not cause rebound headaches from overuse - (answer)Propranolol.
Best option for menstrual migraine - (answer)Low dose estrogen about 3 days prior to menses.
Food that can trigger migraines - (answer)Hot dog.
Medication that is a Serotonin 1B1D receptor agonist - (answer)Sumatriptan.
Side effect of Butterbur in migraine therapy - (answer)Liver damage.
Three main classes of opioid receptors - (answer)Mu, Kappa, Delta.
Reversal of effects caused by opioid agonists - (answer)Naloxone.
, NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Medications used to treat OIC - (answer)Naloxegol, Methylinaltrexone, Lubiprostone.
Definition of tolerance - (answer)Increased doses of a med needed to obtain the same response.
Medication used for opioid abuse - (answer)Naltrexone.
Euphoria induced by morphine - (answer)An exaggerated sense of well-being caused by the activation of
mu receptors.
Medication given nasally for migraines - (answer)Butorphanol.
Mechanism of NSAIDs - (answer)Inhibition of the cyclo-oxygenase enzyme.
Second generation Cox 2 inhibitors - (answer)Suppress inflammation and cause less risk for gastric
ulceration than Cox 1.
Glucocorticoids - (answer)Medications that should not be given with ASA include Glucocorticoids.
Acetaminophen overdose treatment - (answer)The medication given for acetaminophen overdose is
Acetylcysteine.
Nonendocrine therapeutic uses for glucocorticoids - (answer)Uses include RA, SLE, IBS, Bursitis, OA,
Gout, and Disorders of the eye.
Prolonged use of glucocorticoids - (answer)The danger of prolonged use is adrenal insufficiency.
Solutions
Paroxetine - (answer)An SSRI that may cause erectile dysfunction.
Ethosuximide Monitoring - (answer)Patients should be monitored for blood dyscrasias which are
uncommon but possible.
Lamotrigine and OCPs Interaction - (answer)OCPs can reduce lamotrigine levels, requiring an increase in
the dose of lamotrigine.
Tricyclic Antidepressants Caution - (answer)Should be prescribed cautiously in patients with CAD.
Onset of Action Symptoms for SSRIs - (answer)Patients may feel a bit of nausea, which resolves in about
1 week.
Pediatric Dosing Information - (answer)There is a lack of evidence-based literature on the safe and
effective use of medications in children.
Neonates and Protein-Bound Drugs - (answer)Protein binding is decreased in neonates, increasing the
amount of free drug available.
Adult Renal Function Age - (answer)Adult levels of renal function are achieved at 12 months.
Beers List - (answer)A list that identifies drugs with a high likelihood of causing adverse effects in the
elderly.
Gastric Acidity in Pediatric Patients - (answer)Gastric acidity does not reach adult values for 2 years.
Complications to Drug Therapy in the Elderly - (answer)Include altered pharmacokinetics, multiple and
severe illnesses, multiple-drug therapy, and poor adherence.
,NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Altered Absorption in the Elderly - (answer)May result in a delay in drug response.
Factors Altering Drug Distribution in the Elderly - (answer)Include increased body fat, decreased
percentage of lean body mass, decreased total body water, and reduced concentration of serum
albumin.
Adverse Drug Reactions in the Elderly - (answer)The most important cause of adverse drug reactions in
the elderly is polypharmacy.
Bupropion - (answer)An alternative medication that can be added to help with erectile dysfunction
caused by SSRIs.
Increased Seizure Activity with Ethosuximide - (answer)Ethosuximide can induce seizures, so increased
seizure activity should be monitored.
Renal Dysfunction Monitoring - (answer)Patients on ethosuximide should be monitored for renal
dysfunction.
Weight Gain with OCPs - (answer)OCPs can cause weight gain, which may be a concern for patients
taking lamotrigine.
Hepatotoxicity with Ethosuximide - (answer)Hepatotoxicity is a potential risk, but uncommon.
Contraceptive Failure with OCPs - (answer)OCPs may lead to contraceptive failure when interacting with
lamotrigine.
Insomnia with SSRIs - (answer)Patients may experience insomnia for a week after starting SSRIs.
FDA and Pediatric Dosing - (answer)The FDA does not require pediatric dosing information for all
medications.
,NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Free Drug Availability in Neonates - (answer)Decreased protein binding in neonates increases the
amount of free drug available.
Proper index of renal function in the elderly - (answer)Creatinine clearance or GFR.
Factors underlying increase in adverse reactions in geriatric population - (answer)Polypharmacy, severe
illness, multiple pathologies, greater use of drugs that have a low therapeutic index, inadequate
supervision, poor patient adherence.
Maximum amount of Sumatriptan that can be taken in 1 day - (answer)200 mg.
Properties determining anesthetic penetration of axon membrane - (answer)Molecular size, lipid
solubility, degree of ionization at tissue pH.
Medication that will not cause rebound headaches from overuse - (answer)Propranolol.
Best option for menstrual migraine - (answer)Low dose estrogen about 3 days prior to menses.
Food that can trigger migraines - (answer)Hot dog.
Medication that is a Serotonin 1B1D receptor agonist - (answer)Sumatriptan.
Side effect of Butterbur in migraine therapy - (answer)Liver damage.
Three main classes of opioid receptors - (answer)Mu, Kappa, Delta.
Reversal of effects caused by opioid agonists - (answer)Naloxone.
, NURS 5334 Advanced Pharm Final Exam Latest Updates | Questions And Answers Latest
Solutions
Medications used to treat OIC - (answer)Naloxegol, Methylinaltrexone, Lubiprostone.
Definition of tolerance - (answer)Increased doses of a med needed to obtain the same response.
Medication used for opioid abuse - (answer)Naltrexone.
Euphoria induced by morphine - (answer)An exaggerated sense of well-being caused by the activation of
mu receptors.
Medication given nasally for migraines - (answer)Butorphanol.
Mechanism of NSAIDs - (answer)Inhibition of the cyclo-oxygenase enzyme.
Second generation Cox 2 inhibitors - (answer)Suppress inflammation and cause less risk for gastric
ulceration than Cox 1.
Glucocorticoids - (answer)Medications that should not be given with ASA include Glucocorticoids.
Acetaminophen overdose treatment - (answer)The medication given for acetaminophen overdose is
Acetylcysteine.
Nonendocrine therapeutic uses for glucocorticoids - (answer)Uses include RA, SLE, IBS, Bursitis, OA,
Gout, and Disorders of the eye.
Prolonged use of glucocorticoids - (answer)The danger of prolonged use is adrenal insufficiency.
