Chapter 18: Substance Misuse
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. A 38-year-old male has been using the “cold turkey” approach to stop smoking. Although he hasn’t
smoked for 6 months, he tells the nurse that he still feels strong cigarette cravings and wonders whether
he will ever get over the cravings. Which statement is true?
a. The cravings will never stop.
b. The cravings may persist for months to years.
c. The cravings indicate that he has been using nicotine.
d. The cravings indicate that he is about to experience nicotine withdrawal.
ANS: B
Cigarette cravings may persist for months after nicotine withdrawal. “The cravings will never stop”, “The
cravings indicate that he has been using nicotine,” and “The cravings indicate that he is about to
experience nicotine withdrawal” are false statements.
DIF: Cognitive Level: Application
2. A patient in a rehabilitation centre is beginning to experience opioid withdrawal symptoms. What
would you expect to be ordered for this patient’s treatment?
a. diazepam (Valium®)
b. methadone hydrochloride
c. disulfiram (Antabuse®) protocol
d. Antidepressant therapy
ANS: B
Opioid withdrawal can be managed with either methadone or clonidine hydrochloride (Catapres®).
Diazepam and disulfiram are used for treatment of alcoholism. Antidepressant therapy is used for
smoking-cessation programs.
DIF: Cognitive Level: Comprehension
3. If an individual drinks alcohol while on disulfiram (Antabuse) therapy, which will most likely occur?
a. Euphoria
b. Vomiting
c. Hypertension
, d. Hypoventilation
ANS: B
Nausea and copious vomiting occur, and occur quickly, when disulfiram is used with alcohol.
DIF: Cognitive Level: Comprehension
4. A patient has been taking naltrexone (ReVia®) as part of the treatment for addiction to heroin.
Which statement is true in this case?
a. Naltrexone will prevent the patient’s cravings for opioid drugs.
b. Naltrexone will work as a safer substitute for the heroin until the patient completes withdrawal.
c. The patient will experience hypertension and severe nausea if the patient takes heroin while on
naltrexone.
d. If opioid drugs are used while taking naltrexone, euphoria is not produced; thus, the drug’s
effects are lost.
ANS: D
Naltrexone works to eliminate the euphoria that occurs with opioid drug use. Therefore, the reinforcing
effect of the drug is lost when the drug is taken while an opioid is being used.
DIF: Cognitive Level: Analysis
5. During a substance abuse lecture for teenage girls, the nurse is asked about “roofies.” This slang
term refers to what substance?
a. Cocaine
b. flunitrazepam
c. hydromorphone
d. Methamphetamine
ANS: B
Flunitrazepam (Rohypnol®) is a benzodiazepine that has recently gained popularity as a recreational
drug. It is commonly called
“roofies” and is also known as the “date rape” drug.
DIF: Cognitive Level: Comprehension
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. A 38-year-old male has been using the “cold turkey” approach to stop smoking. Although he hasn’t
smoked for 6 months, he tells the nurse that he still feels strong cigarette cravings and wonders whether
he will ever get over the cravings. Which statement is true?
a. The cravings will never stop.
b. The cravings may persist for months to years.
c. The cravings indicate that he has been using nicotine.
d. The cravings indicate that he is about to experience nicotine withdrawal.
ANS: B
Cigarette cravings may persist for months after nicotine withdrawal. “The cravings will never stop”, “The
cravings indicate that he has been using nicotine,” and “The cravings indicate that he is about to
experience nicotine withdrawal” are false statements.
DIF: Cognitive Level: Application
2. A patient in a rehabilitation centre is beginning to experience opioid withdrawal symptoms. What
would you expect to be ordered for this patient’s treatment?
a. diazepam (Valium®)
b. methadone hydrochloride
c. disulfiram (Antabuse®) protocol
d. Antidepressant therapy
ANS: B
Opioid withdrawal can be managed with either methadone or clonidine hydrochloride (Catapres®).
Diazepam and disulfiram are used for treatment of alcoholism. Antidepressant therapy is used for
smoking-cessation programs.
DIF: Cognitive Level: Comprehension
3. If an individual drinks alcohol while on disulfiram (Antabuse) therapy, which will most likely occur?
a. Euphoria
b. Vomiting
c. Hypertension
, d. Hypoventilation
ANS: B
Nausea and copious vomiting occur, and occur quickly, when disulfiram is used with alcohol.
DIF: Cognitive Level: Comprehension
4. A patient has been taking naltrexone (ReVia®) as part of the treatment for addiction to heroin.
Which statement is true in this case?
a. Naltrexone will prevent the patient’s cravings for opioid drugs.
b. Naltrexone will work as a safer substitute for the heroin until the patient completes withdrawal.
c. The patient will experience hypertension and severe nausea if the patient takes heroin while on
naltrexone.
d. If opioid drugs are used while taking naltrexone, euphoria is not produced; thus, the drug’s
effects are lost.
ANS: D
Naltrexone works to eliminate the euphoria that occurs with opioid drug use. Therefore, the reinforcing
effect of the drug is lost when the drug is taken while an opioid is being used.
DIF: Cognitive Level: Analysis
5. During a substance abuse lecture for teenage girls, the nurse is asked about “roofies.” This slang
term refers to what substance?
a. Cocaine
b. flunitrazepam
c. hydromorphone
d. Methamphetamine
ANS: B
Flunitrazepam (Rohypnol®) is a benzodiazepine that has recently gained popularity as a recreational
drug. It is commonly called
“roofies” and is also known as the “date rape” drug.
DIF: Cognitive Level: Comprehension
