(Latest ): Advanced
Pharmacology Fundamentals - Chamberlain
Which of the following agents is the first-line treatment for hyperthyroidism or
Grave's disease?
a. Metoprolol
b. Methimazole
c. Allopurinol
d. Levothyroxine - ANSWER b
Which of the following agents is the preferred treatment option for thyroid storm?
a. Iodine-131
b. Methylphenidate
c. Levothyroxine
d. PTU - ANSWER d
Which laboratory tests should be completed before prescribing methimazole?
Select all that apply.
a. thyroid-stimulating hormone (TSH)
b. CMP
c. free thyroxine (T4)
d. free triiodothyronine (T3)
e. CBC
f. LFTs - ANSWER a, c, d, e, f
,Sabrina is seen one year later and reports that she has developed atrial fibrillation
and was put on warfarin by a new cardiologist. What monitoring concerns are
associated with taking warfarin?
a. Vitamin K
b. INR
c. Creatinine
d. Lipid Panel - ANSWER b
Which of the following agents is the first-line treatment for hyothyroidism?
a. Methimazole
b. Allopurinol
c. Metoprolol
d. Levothyroxine - ANSWER d
Hypothyroid treatment in infants - ANSWER Hormone replacement
therapy should last 3 years and then stop for 4 weeks to allow for follow-up
testing.
Hypothyroid treatment in pregnancy - ANSWER Should be screened and
treated as soon as possible and may require increased dosages for a period of 4-12
weeks.
hypothyroid treatment in adults - ANSWER Lifelong hormone
replacement is needed.
Cecilia is started on levothyroxine 100 micrograms daily. When should her TSH be
re-checked?
a. 6 weeks
b. 8 weeks
c. 4 weeks
, d. 2 weeks - ANSWER a
Once her labs reveal that her thyroid is euthyroid and her dose can be maintained at
the current level, at what interval should her TSH be re-checked?
a. every 12 months
b. every 18 months
c. every 6 months
d. every 24 months - ANSWER a
What medications reduce the absorption of levothyroxine - ANSWER
Histamine 2 (H2) receptor blockers (e.g., cimetidine [Tagamet])
Proton pump inhibitors (e.g., lansoprazole [Prevacid])
Sucralfate (Carafate)
Colestipol (Colestid)
Aluminum-containing antacids (e.g., Maalox, Mylanta),
Calcium supplements (e.g., Tums, Os-Cal)
Iron supplements (e.g., ferrous sulfate)
Magnesium salts
Orlistat (Xenical)
What medications accelerate the absorption of levothyroxine - ANSWER
Phenytoin (Dilantin)
Carbamazepine (Tegretol, Carbatrol)
Rifampin (Rifadin)
Sertraline (Zoloft)
Phenobarbital
Drugs whose metabolism is altered by levothyroxine - ANSWER
Warfarin
Catecholamines
Insulin
Digoxin