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Examen

PC707 MODULE BRAND NEW EXAM QUESTIONS WITH VERIFIED ANSWERS

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Escrito en
2025/2026

PC707 MODULE BRAND NEW EXAM QUESTIONS WITH VERIFIED ANSWERS

Institución
PC707
Grado
PC707











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Institución
PC707
Grado
PC707

Información del documento

Subido en
20 de agosto de 2025
Número de páginas
33
Escrito en
2025/2026
Tipo
Examen
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PC707 MODULE 1 2025-2026 BRAND NEW EXAM
QUESTIONS WITH VERIFIED ANSWERS


What is the difference between type 1 allergic rash and morbilliform rash? -
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correct-answer--type 1 allergic rash--hives, wheals, itchy, type 1 hypersensitivity
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-morbilliform rash--most likely due to a drug reaction, looks like the measles,
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|"drug eruption", type IV delayed hypersensitivity
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What is a type 2 hypersensitivity? - correct-answer--IgG or IgM mediated
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-Ex: heparin induced thrombocytopenia
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-will resolve when the drug is stopped
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What is type 3 hypersensitivity? - correct-answer--Immune complex mediated
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-Ex: serum sickness
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-will resolve when the drug is stopped
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What is type 4 hypersensitivity? - correct-answer--Cell mediated (cytotoxic t cells)
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-delayed response |

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-diffuse, bilateral, symmetrical | |




-Ex: drug rash, contact dermatitis, steven-johnson syndrome
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What is a pseudo allergy? - correct-answer--mast cell degranulation by a non-IgE
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mediated mechanism
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-Ex: opiate analgesic causes direct mast cell activation--causing itching
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What does the QT interval represent? - correct-answer-ventricular depolarization
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and repolarization
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A longer QT interval increases the risk of what? - correct-answer--ventricular
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dysrhythmias (particularly Torsades de pointe)
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-sudden cardiac death | |




Who is at an increased risk of a long QT interval? - correct-answer--females
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-electrolyte imbalances (hypokalemia, hypomagnesemia, hypocalcemia)
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-renal or hepatic problems
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-taking multiple drugs that can prolong QT interval
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-grapefruit juice that might inhibit metabolism of drugs that prolong QT interval
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-diuretic use (reduces electrolytes)| | |

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-bradycardia
-underlying cardiac disease | |




-digitalis therapy |




-family history of long QT syndrome
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-congenital long QT syndrome | | |




What factors can impact pharmacokinetics, pharmacodynamics, drug efficacy and
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likelihood of drug reactions? - correct-answer--age, sex, weight, genetics, diet, co-
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existing diseases, etc.
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Why are pharmaceutical companies less likely to research children? - correct-
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answer--ethical risks
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-health risks |




-cost




Why are infants at a higher risk of adverse effects from drugs? - correct-answer--
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organ immaturity
| |




-under-developed blood brain barrier | | |




-variable peristalsis |




-variable blood flow to muscles
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-increased total % body water (affects distribution)
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-reduced metabolism |




What is polypharmacy? - correct-answer-use of multiple medications
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Number of drug reactions is closely related to number of drugs a person is taking.
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True or false? - correct-answer-True
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What are some prescribing issues with the elderly? - correct-answer--
| | | | | | | | |


polypharmacy
|




-disease-drug reactions (Ex: cirrhosis and tylenol) | | | | |




-physiologic changes (Ex: renal & hepatic dysfunction)
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-multiple prescriptions from different specialities
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-poor adherence |




What is the Beers criteria? - correct-answer--lists potentially inappropriate drugs
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that lead to adverse effects in the elderly
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-particularly in those greater than 65 years old | | | | | | |




-not applicable to those in hospice or palliative care
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-a tool not a guideline--must use your own clinical judgment
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