MIMG 185A Lecture 1 Exam with |!! |!! |!! |!! |!! |!!
accurate detailed solutions |!! |!!
What are the major components of the Innate and Adaptive Immune
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
system respectively? - correct answer✔✔Innate - Barriers, Phagocytes,
|!! |!! |!! |!! |!! |!! |!! |!!
Pattern Recognition Molecules; Adaptive - Lymphocytes, antigen-specific
|!! |!! |!! |!! |!! |!! |!!
receptors, antibodies. |!!
What are some of the soluble factors involved in innate immunity? -
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
correct answer✔✔1) lysosome - found in mucous, cleaves bacterial
|!! |!! |!! |!! |!! |!! |!! |!! |!!
peptidoglycan
2) interferons - antiviral effects, produced by infected cells
|!! |!! |!! |!! |!! |!! |!! |!!
3) complement - group of proteins, involved in bacterial lysis.
|!! |!! |!! |!! |!! |!! |!! |!! |!!
Neutrophils - correct answer✔✔50-60% of WBCS |!! |!! |!! |!! |!!
phagocytic
Fc receptors
|!!
short lived |!!
Mast Cells/Basophils/Eosinophils - correct answer✔✔Highly granular
|!! |!! |!! |!! |!!
Granules contain mediators |!! |!!
FCR's (Fc receptors - usually that bind to IgE)
|!! |!! |!! |!! |!! |!! |!! |!! |!!
If IgE cross linked, release mediators
|!! |!! |!! |!! |!!
Monocytes/Macrophages - correct answer✔✔Phagocytic |!! |!! |!!
FcR binding to Ab Ag complex
|!! |!! |!! |!! |!!
AG presentation
|!!
, Initiates T cell response |!! |!! |!!
Dendritic Cells - correct answer✔✔found all over body |!! |!! |!! |!! |!! |!! |!!
long process, intercalate between cells
|!! |!! |!! |!!
also found in tissues
|!! |!! |!!
trap ag on surface, traffic to lymph nodes
|!! |!! |!! |!! |!! |!! |!!
present AG and aid differentiation |!! |!! |!! |!!
what is the difference between a basophils and an eosinophil? - correct
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
answer✔✔Basophils react with foreign substances and are involved with |!! |!! |!! |!! |!! |!! |!! |!! |!!
inflammation. They release histamine and heparin. Histamine causes |!! |!! |!! |!! |!! |!! |!! |!!
dilation of blood vessels at the inflammation site, and heparin prevents
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
blood clotting. Eosinophils are phagocytes - they eat foreign substances
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
like rogue proteins and immune complexes.
|!! |!! |!! |!! |!!
what is the difference between a monocyte and macrophage? - correct
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
answer✔✔monocyte is the name of the cell that circulates through blood |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
macrophage is name for monocyte once it has reached a particular organ |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
or tissue and has become differentiated!
|!! |!! |!! |!! |!!
How is phagocytosis related to endocytosis? - correct
|!! |!! |!! |!! |!! |!! |!! |!!
answer✔✔Phagocytosis is one type of endocytosis.If the engulfed material |!! |!! |!! |!! |!! |!! |!! |!! |!!
is liquid then phagosytosis is called pinocytosis, and if it is solid, it is
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
called phagocytosis. |!!
Phagogocytosis involved engulfment and degradation in the lysosome |!! |!! |!! |!! |!! |!! |!!
Binding to TLRs - correct answer✔✔will activate the innate immune
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
system!
Characteristics of inflammation? - correct answer✔✔increase in blood |!! |!! |!! |!! |!! |!! |!! |!!
vessel diameter |!!
accurate detailed solutions |!! |!!
What are the major components of the Innate and Adaptive Immune
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
system respectively? - correct answer✔✔Innate - Barriers, Phagocytes,
|!! |!! |!! |!! |!! |!! |!! |!!
Pattern Recognition Molecules; Adaptive - Lymphocytes, antigen-specific
|!! |!! |!! |!! |!! |!! |!!
receptors, antibodies. |!!
What are some of the soluble factors involved in innate immunity? -
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
correct answer✔✔1) lysosome - found in mucous, cleaves bacterial
|!! |!! |!! |!! |!! |!! |!! |!! |!!
peptidoglycan
2) interferons - antiviral effects, produced by infected cells
|!! |!! |!! |!! |!! |!! |!! |!!
3) complement - group of proteins, involved in bacterial lysis.
|!! |!! |!! |!! |!! |!! |!! |!! |!!
Neutrophils - correct answer✔✔50-60% of WBCS |!! |!! |!! |!! |!!
phagocytic
Fc receptors
|!!
short lived |!!
Mast Cells/Basophils/Eosinophils - correct answer✔✔Highly granular
|!! |!! |!! |!! |!!
Granules contain mediators |!! |!!
FCR's (Fc receptors - usually that bind to IgE)
|!! |!! |!! |!! |!! |!! |!! |!! |!!
If IgE cross linked, release mediators
|!! |!! |!! |!! |!!
Monocytes/Macrophages - correct answer✔✔Phagocytic |!! |!! |!!
FcR binding to Ab Ag complex
|!! |!! |!! |!! |!!
AG presentation
|!!
, Initiates T cell response |!! |!! |!!
Dendritic Cells - correct answer✔✔found all over body |!! |!! |!! |!! |!! |!! |!!
long process, intercalate between cells
|!! |!! |!! |!!
also found in tissues
|!! |!! |!!
trap ag on surface, traffic to lymph nodes
|!! |!! |!! |!! |!! |!! |!!
present AG and aid differentiation |!! |!! |!! |!!
what is the difference between a basophils and an eosinophil? - correct
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
answer✔✔Basophils react with foreign substances and are involved with |!! |!! |!! |!! |!! |!! |!! |!! |!!
inflammation. They release histamine and heparin. Histamine causes |!! |!! |!! |!! |!! |!! |!! |!!
dilation of blood vessels at the inflammation site, and heparin prevents
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
blood clotting. Eosinophils are phagocytes - they eat foreign substances
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
like rogue proteins and immune complexes.
|!! |!! |!! |!! |!!
what is the difference between a monocyte and macrophage? - correct
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
answer✔✔monocyte is the name of the cell that circulates through blood |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
macrophage is name for monocyte once it has reached a particular organ |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
or tissue and has become differentiated!
|!! |!! |!! |!! |!!
How is phagocytosis related to endocytosis? - correct
|!! |!! |!! |!! |!! |!! |!! |!!
answer✔✔Phagocytosis is one type of endocytosis.If the engulfed material |!! |!! |!! |!! |!! |!! |!! |!! |!!
is liquid then phagosytosis is called pinocytosis, and if it is solid, it is
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
called phagocytosis. |!!
Phagogocytosis involved engulfment and degradation in the lysosome |!! |!! |!! |!! |!! |!! |!!
Binding to TLRs - correct answer✔✔will activate the innate immune
|!! |!! |!! |!! |!! |!! |!! |!! |!! |!!
system!
Characteristics of inflammation? - correct answer✔✔increase in blood |!! |!! |!! |!! |!! |!! |!! |!!
vessel diameter |!!
