2025/2026 Edition | 100+ Real Questions with
Verified Correct Answers | Graded A+ |
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HESI Medical-Surgical Nursing Final — Comprehensive Review of Adult Health,
Pathophysiology, Surgical Care, Critical Thinking, Clinical Judgement, Pharmacology, and
Emergency Interventions | Expert-Verified Q&A | NGN-Ready | High-Score Certified
Introduction
This document provides the complete and most up-to-date 2025/2026 EVOLVE Elsevier HESI
Med-Surg Final Exam content, featuring over 100 real exam questions with verified correct
answers. The material covers all major medical-surgical domains, ensuring full preparedness for
clinical application and NGN-style questions. All responses have been accuracy-checked to
guarantee optimal performance and exam success.
Answer Format
All correct answers are highlighted in bold and green, with concise rationales that reinforce
critical nursing concepts, clinical reasoning, and safe patient care strategies.
HESI Med-Surg Final Exam | Verified 2025/2026 Content | Exam-Aligned | 100%
Pass-Ready
Question 1
A patient with chest pain has an ECG showing ST elevation. What is the priority?
A) Administer aspirin
B) Obtain a chest X-ray
C) Start IV fluids
D) Prepare for PCI
D) Prepare for PCI
Rationale: ST elevation indicates an acute MI, requiring urgent PCI to restore blood flow.
Question 2
A nurse is caring for a patient on heparin. Which lab value to monitor?
A) Hemoglobin
B) aPTT
C) Creatinine
D) Glucose
,B) aPTT
Rationale: aPTT monitors heparin’s anticoagulant effect.
Question 3
A patient post-appendectomy has a fever. What is the priority?
A) Administer antibiotics
B) Assess for wound infection
C) Increase fluids
D) Monitor vital signs
B) Assess for wound infection
Rationale: Fever may indicate an infection, requiring assessment first.
Question 4
Which sign suggests a patient has hypovolemic shock?
A) Hypertension
B) Tachycardia
C) Warm skin
D) Normal urine output
B) Tachycardia
Rationale: Tachycardia compensates for decreased blood volume.
Question 5
A nurse is teaching a patient about warfarin. What food to avoid?
A) Leafy greens
B) Chicken
C) Rice
D) Apples
A) Leafy greens
Rationale: High vitamin K in leafy greens can reduce warfarin’s effectiveness.
Question 6
A patient with diabetes has a blood sugar of 50 mg/dL. What to do first?
A) Administer insulin
B) Give oral glucose
C) Start an IV
D) Recheck in 1 hour
B) Give oral glucose
Rationale: Oral glucose is the first step for a conscious patient with hypoglycemia.
Question 7
Which intervention is priority for a patient with a pulmonary embolism?
A) Administer heparin
B) Perform a CT scan
C) Start oxygen
D) Elevate legs
C) Start oxygen
Rationale: Oxygen addresses hypoxemia, the immediate concern.
, Question 8
A nurse is assessing a patient with a cast. Which finding is abnormal?
A) Mild warmth
B) Cool, pale fingers
C) Normal sensation
D) Slight swelling
B) Cool, pale fingers
Rationale: Cool, pale fingers suggest impaired circulation.
Question 9
Which medication is used to treat hypertension?
A) Lisinopril
B) Metformin
C) Levothyroxine
D) Insulin
A) Lisinopril
Rationale: Lisinopril is an ACE inhibitor for blood pressure control.
Question 10
A patient with a head injury has unequal pupils. What is the priority?
A) Administer mannitol
B) Assess for increased ICP
C) Start an IV
D) Perform a CT scan
B) Assess for increased ICP
Rationale: Unequal pupils may indicate rising intracranial pressure.
Question 11
Which lab value indicates renal failure?
A) Elevated BUN and creatinine
B) Low potassium
C) High hemoglobin
D) Normal glucose
A) Elevated BUN and creatinine
Rationale: Elevated levels suggest impaired kidney function.
Question 12
A nurse is preparing to administer a blood transfusion. What to check first?
A) Patient ID
B) Blood type
C) IV site
D) Vital signs
A) Patient ID
Rationale: Verifying ID prevents transfusion reactions.
Question 13
Which sign suggests a patient has sepsis?