ACTUAL MARYVILLE NURS 615 PHARM EXAM 1 |2025-2026 LATEST
UPDATED| REAL EXAM QUESTIONS AND ANSWERS | 100% RATED
CORRECT | 100% VERFIED | ALREADY GRADED A+
what the drug does to the body - (answer)Pharmacodynamics
what the body does to the drug (absorption, distribution, metabolism, excretion) -
(answer)pharmacokinetics
how is the drug entered into the body? - (answer)absorption
which substance is most likely to be absorbed in the intestines rather than in the stomach? -
(answer)sodium bicarb
what happens to drugs if there is kidney insufficency - (answer)they are not eliminated properly.
There can be a build up which can cause a stronger effect, longer effect, and toxicity
what does absorption of a drug depend on? - (answer)membrane penetration, lipid solubility, and
ionization (which depends on pH)
,drugs that are ionized are ____ - (answer)hydrophilic
drugs that are unionized are ____ - (answer)lipophilic
___philic drugs absorb easily across membranes - (answer)lipophilic
membrane penetration, how things diffuse across - (answer)distribution
Lipophilic drugs typically go through membranes _____ - (answer)passively
drugs that are protein bound require a certain amount of ___ in the blood - (answer)albumin
drugs are not ___ when they are bound to proteins - (answer)active
only unbound/free drugs can ___ - (answer)act
what is first pass effect - (answer)when drugs are taken orally they must first pass through the
liver and then be metabolized; whatever is left after metabolism is sent on to circulation
,Not enough albumin or impaired kidney/liver function can cause? - (answer)drug toxicity
what does distribution depend on - (answer)the type of tissue the drug needs to distribute to for
its actions
these kinds of drugs have a very low volume of distribution because they tend to roam freely in
the circulation and are cleared by the kidneys - (answer)hydrophilic
these drugs have a high volume of distribution are a cleared by the liver with high intracellular
and tissue penetration - (answer)lipophilic
___ has an effect on lipophilic drugs so they should be given using total body weight -
(answer)obesity
hydrophilic drugs should be dosed using _______ - (answer)adjusted/ideal body weight
which kinds of drugs are more apt to cross the BBB and placenta? why? - (answer)lipophilic;
smaller and typically unionized
, drugs absorbed at a higher pH will be ____ so that it can make it to the small intestine -
(answer)encapsulated
drugs that absorb at a lower ph will not be in a capsule and will absorb in the ... -
(answer)stomach
pH of the stomach - (answer)1-3.5
pH of the small intestine - (answer)3+
this type of drug is ionized, bigger particles, and does not easily cross membranes -
(answer)hydrophilic
this type of drug is non ionized, is smaller, and moves easily across membranes -
(answer)lipophilic
what kind of effect do protein bound drugs have? why? - (answer)a longer and more steady
effect bc the proteins bind for a while then let go... not all of the drug will bind which will mean
a more even release and distribution
UPDATED| REAL EXAM QUESTIONS AND ANSWERS | 100% RATED
CORRECT | 100% VERFIED | ALREADY GRADED A+
what the drug does to the body - (answer)Pharmacodynamics
what the body does to the drug (absorption, distribution, metabolism, excretion) -
(answer)pharmacokinetics
how is the drug entered into the body? - (answer)absorption
which substance is most likely to be absorbed in the intestines rather than in the stomach? -
(answer)sodium bicarb
what happens to drugs if there is kidney insufficency - (answer)they are not eliminated properly.
There can be a build up which can cause a stronger effect, longer effect, and toxicity
what does absorption of a drug depend on? - (answer)membrane penetration, lipid solubility, and
ionization (which depends on pH)
,drugs that are ionized are ____ - (answer)hydrophilic
drugs that are unionized are ____ - (answer)lipophilic
___philic drugs absorb easily across membranes - (answer)lipophilic
membrane penetration, how things diffuse across - (answer)distribution
Lipophilic drugs typically go through membranes _____ - (answer)passively
drugs that are protein bound require a certain amount of ___ in the blood - (answer)albumin
drugs are not ___ when they are bound to proteins - (answer)active
only unbound/free drugs can ___ - (answer)act
what is first pass effect - (answer)when drugs are taken orally they must first pass through the
liver and then be metabolized; whatever is left after metabolism is sent on to circulation
,Not enough albumin or impaired kidney/liver function can cause? - (answer)drug toxicity
what does distribution depend on - (answer)the type of tissue the drug needs to distribute to for
its actions
these kinds of drugs have a very low volume of distribution because they tend to roam freely in
the circulation and are cleared by the kidneys - (answer)hydrophilic
these drugs have a high volume of distribution are a cleared by the liver with high intracellular
and tissue penetration - (answer)lipophilic
___ has an effect on lipophilic drugs so they should be given using total body weight -
(answer)obesity
hydrophilic drugs should be dosed using _______ - (answer)adjusted/ideal body weight
which kinds of drugs are more apt to cross the BBB and placenta? why? - (answer)lipophilic;
smaller and typically unionized
, drugs absorbed at a higher pH will be ____ so that it can make it to the small intestine -
(answer)encapsulated
drugs that absorb at a lower ph will not be in a capsule and will absorb in the ... -
(answer)stomach
pH of the stomach - (answer)1-3.5
pH of the small intestine - (answer)3+
this type of drug is ionized, bigger particles, and does not easily cross membranes -
(answer)hydrophilic
this type of drug is non ionized, is smaller, and moves easily across membranes -
(answer)lipophilic
what kind of effect do protein bound drugs have? why? - (answer)a longer and more steady
effect bc the proteins bind for a while then let go... not all of the drug will bind which will mean
a more even release and distribution
