Summary Neuroscience; cells and the internal environment review

WEEK 3
÷




Cell Membrane

phospholipid bilayer
=




human
Average 70kg body weight
'




→



=
18% protein ,
1St .




fat ,
7% minerals t 60% water

to MO
Highly permeable
.




permeability to other substances
-

.




I .




now
,
moaners Favor Effect on
permeability
1 bn passage
At
• 9 side ( above 3mm
)
A lipid solubility Init ) I

*
A
charge lionization ) bb most IMPORTANT



FACTOR
of
Nat
Y or
e.




-


No
charge , lipid soluble ,
small move across all memb .




1
until
water moves freely
IM menus provides thruture to hold fluid e.
g G t Nr
'




malted
.




this in



Composition Body Fluids Impermeable to A- A peptides proteins
inorganic ions ( Kt
.




of sugars , , , ,




(I ) help
-




they have
etc . unless




E- thrown wheer fluid Intracellular Fluid

-Interstitial Fluid
Blood Plasma leader nature depends on an www.on )
Prowls moving substances between Compartments
10W
Not 14mm
① Diffusion
152 143


4- 113 I11 } high
9MM '




H1U moved 2,500 km/h → 0.3mm apart

kt 5 9 157mm
( L 3mm )
←
Hi 9h
Iullisiom [ High ] flow) I
.




= random movement → tune .

Gradient

Protein low v. low
high Lun take place 2
fytlem that separates
.




in
capillary cell
open or awm partition systems
Wall
Membrane
mode
of
enzyme
Intelligent
② filtration
blipidt protein ; selective tellurium '



poms -

-
hole in membrane e.
g kidney
•
Chemical Disequilibrium permeability Phosphate LP0N '
-




ion
.

=
b imbalance of ions 1 chemicals bln dim compartments

↳ Distant composition bll ull memh 's
permeability to molecules varies ↳ excreted in urine
greatly
'