QUESTIONS AND ANSWERS LATEST
UPDATED
Can you prescribe tetracyclines in pregnant patients - No - can cause tooth staining
Patient education for tetracyclines - Photosensitivity. Advise patients to avoid prolonged
exposure to sunlight, to wear protective clothing, and to apply sunscreen to exposed
skin/avoid tanning beds.
Instruct patients not to take this medication together with calcium supplements, milk
products, iron supplements, magnesium-containing laxatives, and most antacids.
Advise patients to notify the provider if diarrhea occurs, as this is an indication of
potentially life-threatening superinfection of the bowel.
Macrolides patient education - increased risk of Torsades due to prolonged QT
Can you take penicillin's if pregnant? - Yes
, Can you prescribe cephalosporins if pregnant? - yes
Patient education needed for cephalosporins - Can promote C diff, instruct patients to
report increase in stool frequency
Which macrolide is ok for pregnancy? - erythromycin
Aminoglycosides patient education (ex. gentamicin, tobramycin, amikacin) - use is
associated with ototoxicity and nephrotoxicity
Prescribing sulfonamides during pregnancy - not safe (especially in first trimester)-
causes birth defects
if taken near term, infant can develop kernicterus (brain damage caused by too much
bilirubin)
Which cephalosporins may induce a disulfiram-like reaction if alcohol is ingested? -
Cefazolin and cefotetan
sulfonamides patient education - complete full course even if symptoms resolved take
with 8-10 glasses of water or noncaffeinated beverages per day to decrease risk of
crystalluria
protect skin from sun no
tanning beds
monitor for hypersensitivity symptoms
sulfonamides renal dosing - Avoid in older adults for For
patients with creatinine clearance <30mL/min:
For patients concurrently prescribed warfarin, avoid trimethoprim/sulfamethoxazole,
macrolides, and ciprofloxacin
do not give if creatine is under 15
Gentamicin (aminoglycoside) - monitor Cr cl in elderly renal
adjustments
If renal dx dose reduces or dosing interval increased
What do we need to be aware of in our female patients of childbearing age with
clindamycin - decrease oral contraceptive activity
Aminoglycosides are safe for what age group - children (infant <8 days old)
Clindamycin can be used as an alternative to what - penicillin
Specific drug to treat aspergillosis - Voriconazole