4C: making and purifying a sample of Aspirin.
and comparing it to industrial manufacture
introduction
Aspirin is a type of medication also known as a nonsteroidal anti-
inflammatory drug (NSAID). It is widely utilized to alleviate pain, decrease
inflammation, and reduce fever.
HOOCC6H4OH + (CH3CO)2O HOOCC 6H4OCOCH3 +
CH3COOH
Salicylic acid + ethanoic anhydride aspirin +
ethanoic acid
Risk assessment of making and purifying aspirin.
Risk Hazard Precautions
Concentrated (sulfuric Can cause skin Wear lab coat, eyes
acid) irritation, protection goggles and
Damage eyes. gloves while using it.
Use it in tiny amounts
under the fume
cupboard.
If by chance it gets
split in hands, wash
hand quickly with cold
water.
Ethanoic anhydride Can cause skin Wear goggles, lab coat
irritation and serious and gloves while using
eyes damage. it.
Use it under the fume
cupboard and use
small, limited
amounts.
glassware Broken glassware can Do not run while
cut hands and cause holding the glassware.
bleeding. Hold it carefully while
moving around or
fitting it in clamp
stand.
Salicylic acid Can cause irritation Wear lab coat, goggles
and damage eyes. and gloves while using
it.
Use a limited small
, amount and use
spatula to transfer it.
If I get any contact
with hands, wash
hands quickly.
ethanol Highly flammable, can Wear gloves, lab coat
cause serious eyes and goggles while
damage and irritation. using it.
Keep it away from
Bunsen burner flames
and hold it carefully
while moving around.
Chairs and bags Chairs and bags not Make sure that the
stuck under the table bags and chairs are
and make someone pushed under the
slip or fall while tables properly and
holding the chemicals out from the range for
like ethanol or anyone to get slip.
concentrated sulfuric
acid/ glassware.
Method used for making aspirin.
In this experiment, the equipment and the method used for the
preparation aspirin includes.
1. Salicylic acid
2. 100 cm3 conical flask
3. Ethanoic acid
4. Concentrated sulfuric acid.
5. 10 cm3 measuring cylinder.
6. Bunsen burner, tripod, and gauze
7. 400 cm3 beaker
8. 250 cm3 beaker
9. Thermometer
10. Filtration equipment
11. Distilled water
12. Spatula
and comparing it to industrial manufacture
introduction
Aspirin is a type of medication also known as a nonsteroidal anti-
inflammatory drug (NSAID). It is widely utilized to alleviate pain, decrease
inflammation, and reduce fever.
HOOCC6H4OH + (CH3CO)2O HOOCC 6H4OCOCH3 +
CH3COOH
Salicylic acid + ethanoic anhydride aspirin +
ethanoic acid
Risk assessment of making and purifying aspirin.
Risk Hazard Precautions
Concentrated (sulfuric Can cause skin Wear lab coat, eyes
acid) irritation, protection goggles and
Damage eyes. gloves while using it.
Use it in tiny amounts
under the fume
cupboard.
If by chance it gets
split in hands, wash
hand quickly with cold
water.
Ethanoic anhydride Can cause skin Wear goggles, lab coat
irritation and serious and gloves while using
eyes damage. it.
Use it under the fume
cupboard and use
small, limited
amounts.
glassware Broken glassware can Do not run while
cut hands and cause holding the glassware.
bleeding. Hold it carefully while
moving around or
fitting it in clamp
stand.
Salicylic acid Can cause irritation Wear lab coat, goggles
and damage eyes. and gloves while using
it.
Use a limited small
, amount and use
spatula to transfer it.
If I get any contact
with hands, wash
hands quickly.
ethanol Highly flammable, can Wear gloves, lab coat
cause serious eyes and goggles while
damage and irritation. using it.
Keep it away from
Bunsen burner flames
and hold it carefully
while moving around.
Chairs and bags Chairs and bags not Make sure that the
stuck under the table bags and chairs are
and make someone pushed under the
slip or fall while tables properly and
holding the chemicals out from the range for
like ethanol or anyone to get slip.
concentrated sulfuric
acid/ glassware.
Method used for making aspirin.
In this experiment, the equipment and the method used for the
preparation aspirin includes.
1. Salicylic acid
2. 100 cm3 conical flask
3. Ethanoic acid
4. Concentrated sulfuric acid.
5. 10 cm3 measuring cylinder.
6. Bunsen burner, tripod, and gauze
7. 400 cm3 beaker
8. 250 cm3 beaker
9. Thermometer
10. Filtration equipment
11. Distilled water
12. Spatula
