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Mcb 252 Old Exam 3

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MCB 252 OLD EXAM 3 MCB 252 OLD EXAM 3

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MCB 252 OLD EXAM 3




1.Do you expect the addition of lantruculin to cells would stop phagocytosis?
: Yes it would stop phagocytosis
2.As discussed in lecture the contractile bundles (sarcomeres) found in
mus- cle cells most likely appeared in evolution before contractile bundles
found in stress fibers: False
3.Intermediate filaments are considered equilibrium polymers as opposed
to actin filaments which are best described as steady state filaments: True
4.As described in lecture because actin filaments are helical, any motor
protein that moves along those filaments must follow a helical path:
False
5.As described in lecture, a polyclonal antibody contains many different
antibodies , each of which recognizes a distinct epitope on the surface of
an antigen: True
6.Profilin binds to which end of the actin monomer?: The plus end
7.Exon shuffling occurs at the level of DNA in the genome; whereas;
splicing occurs at the level of RNA: True
8.As described in lecture, homo sapiens migrated out of Africa before
nean- derthals migrated out of Africa: False
9.In lecture we discussed modular construction of some genes and the
evolution of genes (and proteins) by the addition of domains. As
described in lecture, this process occurs in prokaryotes and eukaryotes:
False
10.All cytoskeletal polymers are multi stranded: True
11.Which property of eukaryotic gene regulatory regions allowed for the
evo- lution of complex regulatory regions?: Enhancers that act over long
distances
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, 12.1. The majority of different colors of fluorescent proteins used by cell
biologist are all naturally occurring proteins that were isolated from
different types of aquatic organisms.
2. As described in lecture, when purifying a protein of interest one needs an
assay that is specific for that particular protein.: 1=False
2=True
13.Congratulations! You finally managed to build a ray gun that allows you
to shrink yourself down to the size of a molecule. Like any normal person,
your first idea is to stand on top of a 4 formin protein. That formin protein
that you are standing on is immobilized on a solid surface. Actin monomers
then start to arrive at the formin upon which you are standing. Looking
down the filament, what do you see?: B. The minus end of the actin
filament is moving away from you.
14.You have now elected to stand on an Arp2/3 complex. The Arp2/3
complex just nucleated a new actin filament, and that daughter filament has
polymer- ized to add several thousand actin subunits. Now you see that a
myosin II




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