HTHS 2240 WSU Final Exam 2 Questions
with Guaranteed Pass Solutions (2025-
2026) Updated.
pharmacokinetic - Answer the measured response to time and dose (absorption, blood levels,
mode of inactivation, etc.) This is described as "what the body does to the drug"
pharmacodynamic - Answer the mechanism of action of how drugs produce their effects. This
is often described as "what the drug does to the body"
absorption - Answer being the fraction of an administered dose that reaches the systemic
circulation
distribution - Answer where the drug goes in the body
T ½(half life) - Answer the time required for the serum drug level to decrease by 50%
Metabolism - Answer the way the drug is broken down
Excretion - Answer the way it is cleared from the body
Drug Cycle - Answer deals with the pharmacokinetic variables (Absorption, Distribution,
Metabolism, and Excretion)
bioavailability - Answer the administered dose of unchanged drug that reaches the systemic
circulation
Albumin - Answer only one of many proteins that exist in the blood, but it is the most
abundant, and its size, shape (sort of roundish), and characteristics make it into a binder of
drugs floating in the plasma
The BBB(Blood Brain Barrier) - Answer built into the anatomy of the cerebral circulation
wherein the capillaries of that system are less permeable to some substances, including some
drugs
, liver - Answer main organ for the metabolism of drugs
First Pass Effect - Answer drugs are chemically changed in the liver
metabolite - Answer the active form of the drug
very young or very old - Answer drugs have longer and greater effects due to liver metabolism
issues
tolerance - Answer iver is "pumped-up," (induced) metabolism of the drug is increased and it
takes a lot more drug to produced the same effect
Kidney's - Answer Most drugs are excreted from the body by the....
"Key" - Answer The chemical that binds to the receptor
"Lock" - Answer The receptor
agonist - Answer If the key turns the lock the drug is said to be an
antagonist - Answer If the drug occupies the lock but doesn't "turn it", it is said to be an
Local effects - Answer largely limited to the site of administration and surrounding tissues.
Systemic effects - Answer drug is "felt", to varying degrees, throughout the body (depending
on which tissues the drug receptors are located)
prednisone - Answer A systemic corticosteroid. The organs are exposed along with the skin
Bronchodilators - Answer used to "open" the lungs (local effect), but they can also cause
nervous "jitters" (systemic effect from absorption of some of the drug into the bloodstream)
with Guaranteed Pass Solutions (2025-
2026) Updated.
pharmacokinetic - Answer the measured response to time and dose (absorption, blood levels,
mode of inactivation, etc.) This is described as "what the body does to the drug"
pharmacodynamic - Answer the mechanism of action of how drugs produce their effects. This
is often described as "what the drug does to the body"
absorption - Answer being the fraction of an administered dose that reaches the systemic
circulation
distribution - Answer where the drug goes in the body
T ½(half life) - Answer the time required for the serum drug level to decrease by 50%
Metabolism - Answer the way the drug is broken down
Excretion - Answer the way it is cleared from the body
Drug Cycle - Answer deals with the pharmacokinetic variables (Absorption, Distribution,
Metabolism, and Excretion)
bioavailability - Answer the administered dose of unchanged drug that reaches the systemic
circulation
Albumin - Answer only one of many proteins that exist in the blood, but it is the most
abundant, and its size, shape (sort of roundish), and characteristics make it into a binder of
drugs floating in the plasma
The BBB(Blood Brain Barrier) - Answer built into the anatomy of the cerebral circulation
wherein the capillaries of that system are less permeable to some substances, including some
drugs
, liver - Answer main organ for the metabolism of drugs
First Pass Effect - Answer drugs are chemically changed in the liver
metabolite - Answer the active form of the drug
very young or very old - Answer drugs have longer and greater effects due to liver metabolism
issues
tolerance - Answer iver is "pumped-up," (induced) metabolism of the drug is increased and it
takes a lot more drug to produced the same effect
Kidney's - Answer Most drugs are excreted from the body by the....
"Key" - Answer The chemical that binds to the receptor
"Lock" - Answer The receptor
agonist - Answer If the key turns the lock the drug is said to be an
antagonist - Answer If the drug occupies the lock but doesn't "turn it", it is said to be an
Local effects - Answer largely limited to the site of administration and surrounding tissues.
Systemic effects - Answer drug is "felt", to varying degrees, throughout the body (depending
on which tissues the drug receptors are located)
prednisone - Answer A systemic corticosteroid. The organs are exposed along with the skin
Bronchodilators - Answer used to "open" the lungs (local effect), but they can also cause
nervous "jitters" (systemic effect from absorption of some of the drug into the bloodstream)
