MSN 611
MSN 611 - Pharm Final Exam Information
GRADED A+ 2025
Nursing Fundamentals
IV route is the fastest
Pharmacokinetics
ADME
1. Absorption: how medication gains access to the body
2. Distribution
3. Metabolism
4. Excretion
1st pass effect
When a drug is metabolized at a specific point in the body, resulting in a lower
concentration of the active substance.
This phenomenon is termed the first-pass effect and is most often described in the
context of absorption of chemicals following ingestion. In general, the first-pass
effect after oral absorption is the result of efficient uptake and metabolism of
compounds by the liver.
Generic vs Brand
A medication only has ONE generic name but can have MULTIPLE brand names
(ex: ibuprofen; MOTRIN/ADVIL)
When should a patient be assessed before administering a medication?
The patient should be assessed right before administration of a drug (ex: assess BP
prior to administering a BP med)
What assessment in a patient needs immediate intervention?
Oliguria or anuria
NSAIDS
MSN 611
, MSN 611
Nephrotoxic & Hepatotoxic
COX-1/COX-2 inhibitors with the exception of Celecoxib
#1 Adverse Effect: GI bleeding (fecal occult blood test)
Acetaminophen
Hepatotoxic
Not an antiinflammatory
Corticosteroids
Different routes--> inhaled, intranasal, IM, topical
Major systemic adverse effects: hyperglycemia, HTN, depressed immune function,
decreased bone density (for these reasons we do NOT like to administer steroids
systemically)
What reasons are steroids used?
Asthma, cancer, nausea, etc.
Serotonin 5-HT Receptor Agonists (-triptans)
Work to treat migraines
Migraines are most common in females
These medications are TERATOGENIC
Contraindicated in patients with cardiac disease, HTN, or taking other medications
such as SSRIs/SNRIs
Opioids
Patients should not be on more than one opioid medication
Can cause bradypnea and hypotension
Long-term side effect: constipation
*Naloxone is used to reverse OD
What other uses do opioids have?
MSN 611
MSN 611 - Pharm Final Exam Information
GRADED A+ 2025
Nursing Fundamentals
IV route is the fastest
Pharmacokinetics
ADME
1. Absorption: how medication gains access to the body
2. Distribution
3. Metabolism
4. Excretion
1st pass effect
When a drug is metabolized at a specific point in the body, resulting in a lower
concentration of the active substance.
This phenomenon is termed the first-pass effect and is most often described in the
context of absorption of chemicals following ingestion. In general, the first-pass
effect after oral absorption is the result of efficient uptake and metabolism of
compounds by the liver.
Generic vs Brand
A medication only has ONE generic name but can have MULTIPLE brand names
(ex: ibuprofen; MOTRIN/ADVIL)
When should a patient be assessed before administering a medication?
The patient should be assessed right before administration of a drug (ex: assess BP
prior to administering a BP med)
What assessment in a patient needs immediate intervention?
Oliguria or anuria
NSAIDS
MSN 611
, MSN 611
Nephrotoxic & Hepatotoxic
COX-1/COX-2 inhibitors with the exception of Celecoxib
#1 Adverse Effect: GI bleeding (fecal occult blood test)
Acetaminophen
Hepatotoxic
Not an antiinflammatory
Corticosteroids
Different routes--> inhaled, intranasal, IM, topical
Major systemic adverse effects: hyperglycemia, HTN, depressed immune function,
decreased bone density (for these reasons we do NOT like to administer steroids
systemically)
What reasons are steroids used?
Asthma, cancer, nausea, etc.
Serotonin 5-HT Receptor Agonists (-triptans)
Work to treat migraines
Migraines are most common in females
These medications are TERATOGENIC
Contraindicated in patients with cardiac disease, HTN, or taking other medications
such as SSRIs/SNRIs
Opioids
Patients should not be on more than one opioid medication
Can cause bradypnea and hypotension
Long-term side effect: constipation
*Naloxone is used to reverse OD
What other uses do opioids have?
MSN 611
