Test Bank For A Manual of Laboratory an
38 38 38 38 38 38 38
Tests 7th Edition Frances T Fischbach.
38 38 38 38 38
, 2
Blood38Studies;38Hematology38and38Coagulation
OVERVIEW38OF38BASIC38BLOOD38HEMATOLOGY38AND38COAGULATI
ON38TESTS
Composition38of38Blood
Blood38Tests
BLOOD38SPECIMEN38COLLECTION38PROCEDURES
Capillary38Puncture38(Skin38Punct
ure)38Venipuncture
NOTE
38NO
TE
Bone38Marrow38Aspiration
BASIC38BLOOD38TESTS
Hemogram
Complete38Blood38Count38(CBC)3
8TESTS38OF38WHITE38BLOOD38C
White38Blood38Cell38Count38(WBC;38Leukocyte38Count)
ELLS
Differential38White38Blood38Cell38Count38(Diff;38Differential38Leukocyte38Count)
NOTE
Segmented38Neutrophils38(Polymorphonuclear38Neutrophils,38PMNs,38Segs,38Polys)
38Eosinophils
Basophils
Monocytes38(Monomorphonuclear38Monocy
tes)
Lymphocytes38(Monomorphonuclear38Lymphocytes);38CD4,38CD838Count;38Plasma
38Cells38Lymphocyte38Immunophenotyping38(T38and38B38Cells)
STAINS38FOR38LEUKEMIAS
Sudan38Black38B38(SBB)38Stain
Periodic38Acid–
Schiff38(PAS)38Stain
Terminal38Deoxynucleotidyl38Transferase38(TDT)3
8Stain38Leukocyte38Alkaline38Phosphatase38(LA
P)38Stain38Tartrate-
Resistant38Acid38Phosphatase38(TRAP)38Stain
TESTS38OF38RED38BLOOD38CELLS
Red38Blood38Cell38Count38(RBC;38Erythrocyte38
Count)38Hematocrit38(Hct);38Packed38Cell38Volu
me38(PCV)38Hemoglobin38(Hb)
Red38Blood38Cell38Indices
Mean38Corpuscular38Volume38(MCV)
Mean38Corpuscular38Hemoglobin38Concentration38(M
CHC)38Mean38Corpuscular38Hemoglobin38(MCH)
Red38Cell38Size38Distribution38Width38(RDW)
Stained38Red38Cell38Examination38(Film;38Stained38Erythrocyte38Exa
mination)38NOTE
Reticulocyte38Count
Sedimentation38Rate38(Sed38Rate);38Erythrocyte38Sedimentation38Rat
e38(ESR)38TESTS38FOR38PORPHYRIA
Erythropoietic38Porphyrins;38Free38Erythrocyte38Protoporphyrin38(FEP)
Porphyrins;38Fractionation38of38Erythrocytes38and38of38Plasma
ADDITIONAL38TESTS38FOR38HEMOLYTIC38
ANEMIA
,Hypercoagulability38States
Disorders38of38Hemostasis
Clinical38Ale
rt38Clinical3
8Alert
Tests38for38Disseminated38Intravascular38Coagulation
38(DIC)38Bleeding38Time38(Ivy38Method;38Template38
Bleeding38Time)38Platelet38Count;38Mean38Platelet38
Volume38(MPV)
Platelet38Aggregation
Thrombin38Time38(TT);38Thrombin38Clotting38Time38(TCT)
Partial38Thromboplastin38Time38(PTT);38Activated38Partial38Thromboplastin38Time38(APTT)
NOTE
Activated38Coagulation38Time38(ACT)38P
rothrombin38Time38(Pro38Time;38PT)38C
oagulant38Factors38(Factor38Assay)38Pla
sminogen38(Plasmin;38Fibrinolysin)
Fibrinolysis38(Euglobulin38Lysis38Time;38Diluted38Whole38Blood38Cl
ot38Lysis)38Fibrin38Split38Products38(FSPs);38Fibrin38Degradation38
Products38(FDPs)
D-
Dimer3 8 Fibrinopeptid
e38A38(FPA)
Prothrombin38Fragment38(F138+382)
Fibrin38Monomers38(Protamine38Sulfate38Test;38Fibrin38Split38Produ
cts)38Fibrinogen
Protein38C38(PC38Antigen)
NOTE
38NO
TE
Protein38S
Antithrombin38III38(AT-
III;38Heparin38Cofactor38Activity)38BIBLIOGRAPHY
OVERVIEW38OF38BASIC38BLOOD38HEMATOLOGY38AND38COAGULATION38TESTS
Composition38of38Blood
The38average38person38circulates38about38538L38of38blood38(1/1338of38body38weight),38of38which3833
238L38is38cells.38Plasma38fluid38derives38from38the38intestines38and38lymphatic38systems38and38provi
cell38movement.38The38cells38are38produced38primarily38by38bone38marrow38and38account38for38bloo
ells38are38classified38as38white38cells38(leukocytes),38red38cells38(erythrocytes),38and38platelets38(thr
cells38are38further38categorized38as38granulocytes,38lymphocytes,38monocytes,38eosinophils,38and38
Before38birth,38hematopoiesis38occurs38in38the38liver.38In38midfetal38life,38the38spleen38and38lymph38
r38role38in38cell38production.38Shortly38after38birth,38hematopoiesis38in38the38liver38ceases,38and38the
he38only38site38of38production38of38erythrocytes,38granulocytes,38and38platelets.38B38lymphocytes38a
38marrow38and38in38the38secondary38lymphoid38organs;38T38lymphocytes38are38produced38in38the38t
Blood38Tests
Tests38in38this38chapter38are38basic38screening38tests38that38address38disorders38of38hemoglobin38(
ction38(hematopoiesis),38synthesis,38and38function.38Blood38and38bone38marrow38examinations38con
means38of38determining38certain38blood38disorders38(anemias,38leukemia38and38porphyrias38disorde
ing38and38clotting),38inflammation,38infection38and38inherited38disorders38of38red38blood38cells,38whit
8platelets.38Specimens38are38obtained38through38capillary38skin38punctures38(finger,38toe,38heel),38d
38arterial38or38venous38sampling,38or38bone38marrow38aspiration.38Specimens38may38be38tested38by
, 4. Wipe38away38the38initial38drop38of38blood.38Collect38subsequent38drops38in38a38microtube38or3
a
38 38 38 38 38 38 38
Tests 7th Edition Frances T Fischbach.
38 38 38 38 38
, 2
Blood38Studies;38Hematology38and38Coagulation
OVERVIEW38OF38BASIC38BLOOD38HEMATOLOGY38AND38COAGULATI
ON38TESTS
Composition38of38Blood
Blood38Tests
BLOOD38SPECIMEN38COLLECTION38PROCEDURES
Capillary38Puncture38(Skin38Punct
ure)38Venipuncture
NOTE
38NO
TE
Bone38Marrow38Aspiration
BASIC38BLOOD38TESTS
Hemogram
Complete38Blood38Count38(CBC)3
8TESTS38OF38WHITE38BLOOD38C
White38Blood38Cell38Count38(WBC;38Leukocyte38Count)
ELLS
Differential38White38Blood38Cell38Count38(Diff;38Differential38Leukocyte38Count)
NOTE
Segmented38Neutrophils38(Polymorphonuclear38Neutrophils,38PMNs,38Segs,38Polys)
38Eosinophils
Basophils
Monocytes38(Monomorphonuclear38Monocy
tes)
Lymphocytes38(Monomorphonuclear38Lymphocytes);38CD4,38CD838Count;38Plasma
38Cells38Lymphocyte38Immunophenotyping38(T38and38B38Cells)
STAINS38FOR38LEUKEMIAS
Sudan38Black38B38(SBB)38Stain
Periodic38Acid–
Schiff38(PAS)38Stain
Terminal38Deoxynucleotidyl38Transferase38(TDT)3
8Stain38Leukocyte38Alkaline38Phosphatase38(LA
P)38Stain38Tartrate-
Resistant38Acid38Phosphatase38(TRAP)38Stain
TESTS38OF38RED38BLOOD38CELLS
Red38Blood38Cell38Count38(RBC;38Erythrocyte38
Count)38Hematocrit38(Hct);38Packed38Cell38Volu
me38(PCV)38Hemoglobin38(Hb)
Red38Blood38Cell38Indices
Mean38Corpuscular38Volume38(MCV)
Mean38Corpuscular38Hemoglobin38Concentration38(M
CHC)38Mean38Corpuscular38Hemoglobin38(MCH)
Red38Cell38Size38Distribution38Width38(RDW)
Stained38Red38Cell38Examination38(Film;38Stained38Erythrocyte38Exa
mination)38NOTE
Reticulocyte38Count
Sedimentation38Rate38(Sed38Rate);38Erythrocyte38Sedimentation38Rat
e38(ESR)38TESTS38FOR38PORPHYRIA
Erythropoietic38Porphyrins;38Free38Erythrocyte38Protoporphyrin38(FEP)
Porphyrins;38Fractionation38of38Erythrocytes38and38of38Plasma
ADDITIONAL38TESTS38FOR38HEMOLYTIC38
ANEMIA
,Hypercoagulability38States
Disorders38of38Hemostasis
Clinical38Ale
rt38Clinical3
8Alert
Tests38for38Disseminated38Intravascular38Coagulation
38(DIC)38Bleeding38Time38(Ivy38Method;38Template38
Bleeding38Time)38Platelet38Count;38Mean38Platelet38
Volume38(MPV)
Platelet38Aggregation
Thrombin38Time38(TT);38Thrombin38Clotting38Time38(TCT)
Partial38Thromboplastin38Time38(PTT);38Activated38Partial38Thromboplastin38Time38(APTT)
NOTE
Activated38Coagulation38Time38(ACT)38P
rothrombin38Time38(Pro38Time;38PT)38C
oagulant38Factors38(Factor38Assay)38Pla
sminogen38(Plasmin;38Fibrinolysin)
Fibrinolysis38(Euglobulin38Lysis38Time;38Diluted38Whole38Blood38Cl
ot38Lysis)38Fibrin38Split38Products38(FSPs);38Fibrin38Degradation38
Products38(FDPs)
D-
Dimer3 8 Fibrinopeptid
e38A38(FPA)
Prothrombin38Fragment38(F138+382)
Fibrin38Monomers38(Protamine38Sulfate38Test;38Fibrin38Split38Produ
cts)38Fibrinogen
Protein38C38(PC38Antigen)
NOTE
38NO
TE
Protein38S
Antithrombin38III38(AT-
III;38Heparin38Cofactor38Activity)38BIBLIOGRAPHY
OVERVIEW38OF38BASIC38BLOOD38HEMATOLOGY38AND38COAGULATION38TESTS
Composition38of38Blood
The38average38person38circulates38about38538L38of38blood38(1/1338of38body38weight),38of38which3833
238L38is38cells.38Plasma38fluid38derives38from38the38intestines38and38lymphatic38systems38and38provi
cell38movement.38The38cells38are38produced38primarily38by38bone38marrow38and38account38for38bloo
ells38are38classified38as38white38cells38(leukocytes),38red38cells38(erythrocytes),38and38platelets38(thr
cells38are38further38categorized38as38granulocytes,38lymphocytes,38monocytes,38eosinophils,38and38
Before38birth,38hematopoiesis38occurs38in38the38liver.38In38midfetal38life,38the38spleen38and38lymph38
r38role38in38cell38production.38Shortly38after38birth,38hematopoiesis38in38the38liver38ceases,38and38the
he38only38site38of38production38of38erythrocytes,38granulocytes,38and38platelets.38B38lymphocytes38a
38marrow38and38in38the38secondary38lymphoid38organs;38T38lymphocytes38are38produced38in38the38t
Blood38Tests
Tests38in38this38chapter38are38basic38screening38tests38that38address38disorders38of38hemoglobin38(
ction38(hematopoiesis),38synthesis,38and38function.38Blood38and38bone38marrow38examinations38con
means38of38determining38certain38blood38disorders38(anemias,38leukemia38and38porphyrias38disorde
ing38and38clotting),38inflammation,38infection38and38inherited38disorders38of38red38blood38cells,38whit
8platelets.38Specimens38are38obtained38through38capillary38skin38punctures38(finger,38toe,38heel),38d
38arterial38or38venous38sampling,38or38bone38marrow38aspiration.38Specimens38may38be38tested38by
, 4. Wipe38away38the38initial38drop38of38blood.38Collect38subsequent38drops38in38a38microtube38or3
a