1
BIO 181 EXAM 4 NOTES - EXAM 4 NOTEs by
prof Daniel
Dna replication- the original strands are used as templates for the synthesis of new
dna.
Origin of replication – a site within a chromosome that serves as a starting point
for dna replication.
Two dna strands unwind at the origin of replication for form a replication bubble.
Within the bubble two replication forks are formed. Dna replication proceeds
outwards from these replication forks, a process called bidirectional replication.
Bacterial chromosomes are small and have a single origin of replication.
Dna helicase used atp to break hydrogen bonds in dna.
Dna polymerase links dna nucleotides together and forms dna polymers
pg. 1
,2
Dna primase is required if a template strand is bare. It makes a rna primer that’s
10 to 12 nucleotides in length.
Deoxynucleoside triphosphate hydrogen bond to the exposed bases in the template
strand
A second feature of dna polymerase is that it can synthesize new dna only in a 5 to
3 direction.
PG. 2
, 3
pg. 3
BIO 181 EXAM 4 NOTES - EXAM 4 NOTEs by
prof Daniel
Dna replication- the original strands are used as templates for the synthesis of new
dna.
Origin of replication – a site within a chromosome that serves as a starting point
for dna replication.
Two dna strands unwind at the origin of replication for form a replication bubble.
Within the bubble two replication forks are formed. Dna replication proceeds
outwards from these replication forks, a process called bidirectional replication.
Bacterial chromosomes are small and have a single origin of replication.
Dna helicase used atp to break hydrogen bonds in dna.
Dna polymerase links dna nucleotides together and forms dna polymers
pg. 1
,2
Dna primase is required if a template strand is bare. It makes a rna primer that’s
10 to 12 nucleotides in length.
Deoxynucleoside triphosphate hydrogen bond to the exposed bases in the template
strand
A second feature of dna polymerase is that it can synthesize new dna only in a 5 to
3 direction.
PG. 2
, 3
pg. 3
