Unit 2 Questions And Answers
Pharmacokinetics m- mAnswer m- mThe mStudy mof mdrug mmovement mthroughout mthe mbody mincludes
m4 mbasic mprocesses: mabsorption, mdistribution, mmetabolism, mexcretion.
Absorption m- mAnswer m- mThe mdrug's mmovement mfrom mthe mblood mto mthe minterstitial mspace mof
mtissues mand mfrom mthere minto mcells.
Metabolism m- mAnswer m- mThe menzymatically mmediated malteration mof mdrug mstructure.
Excretion m- mAnswer m- mThe mmovement mof mdrugs mand mtheir mmetabolites mout mof mthe mbody.
Elimination m- mAnswer m- mThe mcombination mof mmetabolism mand mexcretion
Therapeutic mIndex m- mAnswer m- mThe mrange mof mdoses mat mwhich ma mmedication mis meffective
mwithout madverse mevents.
Half-life m- mAnswer m- mThe mtime mrequired mfor mthe mamount mof ma mdrug mint mthe mbody mto
mdecrease mby m50%.
Pharmacodynamics m- mAnswer m- mThe mstudy mof mthe mbiochemical mand mphysiologic meffects mof
mdrugs mon mthe mbody mand mthe mmolecular mmechanisms mby mwhich mthose meffects mare
mproduced.
Agonist m- mAnswer m- mMolecules mthat mactivate mreceptors.
Antagonist m- mAnswer m- mProduce mtheir meffects mby mpreventing mreceptor mactivation mby
mendogenous mregulatory mmolecules mand mdrugs.