Final Exam Adv Pharm NR568 Questions With Complete
Solutions
Amantadine, Amoxetine, Amitriptyline classes
PD antiviral; also known as strattera for ADHD; TCA
Adverse reaction of Kava
Liver injury requiring transplant
Adverse reaction of Echinacea
Allergic reaction (belongs to plant family: ragweed, asters,
chamomile); Can oppose the effects of immunosuppressant
drugs, compromise drug therapy of tuberculosis, cancer, and
HIV infection
Adverse reactions of black cohosh
Hypotensive effects of antihypertensive drugs, hypoglycemic
effects. May increase risk for liver damage, liver inflammation
that can lead to liver failure
ADHD nonstimulants
Atomoxetine (Strattera), A1 adrenergic agonist: Guanfacine,
Clonidine
ADHD stimulants
dextroamphetamine (adderall), methylphenidate (ritalin)
Adverse reaction with 2nd generation antipsychotics (clozapine)
Agranulocytosis (black box), New onset diabetes, HLD,
Seizures, Myocarditis
,Would should antidepressants not be given alone with Bipolar
Disorder?
Can cause mania or hypomania
Why TCAs be avoided with Bipolar Disorder?
Can worsen mania
Why should caution be taken when combining lithium with
diuretics?
Can cause dehydration and lead to lithium retention
Black box warning: Lithium
Lithium toxicity, Hepatotoxicity, Pancreatitis, Teratogenic
Patient education with Lithium
Maintain hydration, Monitor for signs of toxicity
Examples of Benzodiazepines
Diazepam (Valium)-Lorazepam (Ativan)-Alprazolam (Xanax)
Benzo-like drugs
Zolpidem (Ambien)Zaleplon (Sonata)Eszopiclone
(Lunesta)Phenobarbital
Goal of ADHD stimulants
Increase attention span- Decrease impulsiveness, distractions,
hyperactivity- Improve cognitive function
, Benefit of drug holidays with ADHD meds and when to take
them
- weekends and summertime- allows growth to catch up
Side affect of ADHD medications
- growth delays due to appetite suppression- insomnia (take
before 4pm)
Pros/Cons of ADHD nonstimulants vs stimulants
More convenient to refill since they are not controlled
substances but do not work as well as stimulants
What to monitor for with ADHD nonstimulants?
Suicide ideation in children/adolescents, Liver function
What type of patient would benefit from use of Trazodone as a
sleep aid?
reating insomnia resulting from use of antidepressants that cause
significant CNS stimulation
How does Zaleplon and Zolpidem help insomnia?
It is a benzo-like drug that assists with falling and staying
asleep.
What is Black Cohosh used for?
Treats symptoms of menopause
Drug interactions with black cohosh
Solutions
Amantadine, Amoxetine, Amitriptyline classes
PD antiviral; also known as strattera for ADHD; TCA
Adverse reaction of Kava
Liver injury requiring transplant
Adverse reaction of Echinacea
Allergic reaction (belongs to plant family: ragweed, asters,
chamomile); Can oppose the effects of immunosuppressant
drugs, compromise drug therapy of tuberculosis, cancer, and
HIV infection
Adverse reactions of black cohosh
Hypotensive effects of antihypertensive drugs, hypoglycemic
effects. May increase risk for liver damage, liver inflammation
that can lead to liver failure
ADHD nonstimulants
Atomoxetine (Strattera), A1 adrenergic agonist: Guanfacine,
Clonidine
ADHD stimulants
dextroamphetamine (adderall), methylphenidate (ritalin)
Adverse reaction with 2nd generation antipsychotics (clozapine)
Agranulocytosis (black box), New onset diabetes, HLD,
Seizures, Myocarditis
,Would should antidepressants not be given alone with Bipolar
Disorder?
Can cause mania or hypomania
Why TCAs be avoided with Bipolar Disorder?
Can worsen mania
Why should caution be taken when combining lithium with
diuretics?
Can cause dehydration and lead to lithium retention
Black box warning: Lithium
Lithium toxicity, Hepatotoxicity, Pancreatitis, Teratogenic
Patient education with Lithium
Maintain hydration, Monitor for signs of toxicity
Examples of Benzodiazepines
Diazepam (Valium)-Lorazepam (Ativan)-Alprazolam (Xanax)
Benzo-like drugs
Zolpidem (Ambien)Zaleplon (Sonata)Eszopiclone
(Lunesta)Phenobarbital
Goal of ADHD stimulants
Increase attention span- Decrease impulsiveness, distractions,
hyperactivity- Improve cognitive function
, Benefit of drug holidays with ADHD meds and when to take
them
- weekends and summertime- allows growth to catch up
Side affect of ADHD medications
- growth delays due to appetite suppression- insomnia (take
before 4pm)
Pros/Cons of ADHD nonstimulants vs stimulants
More convenient to refill since they are not controlled
substances but do not work as well as stimulants
What to monitor for with ADHD nonstimulants?
Suicide ideation in children/adolescents, Liver function
What type of patient would benefit from use of Trazodone as a
sleep aid?
reating insomnia resulting from use of antidepressants that cause
significant CNS stimulation
How does Zaleplon and Zolpidem help insomnia?
It is a benzo-like drug that assists with falling and staying
asleep.
What is Black Cohosh used for?
Treats symptoms of menopause
Drug interactions with black cohosh
