Nursing Pharmacology perfect revision
material in question-answer based format.
Guaranteed A+
Absorption - Correct Answers-the process by which drug molecules move from their site of
administration to the blood
Affinity - Correct Answers-the ability of some tissues to attract, accumulate and store drugs in
high concentrations relative to other tissues
blood-brain barrier - Correct Answers-Blood vessels (capillaries) that selectively let certain
substances enter the brain tissue and keep other substances out
diffusion - Correct Answers-process by which molecules tend to move from an area where they
are more concentrated to an area where they are less concentrated
distribution - Correct Answers-the transport of drugs throughout the body after they are
absorbed
drug-protein complexes - Correct Answers-formed when a drugh that binds reversibly to a
plasma protein, particularly albumin, that makes the drug unavailable for distribution to its site
of action
enterohepatic recirculation - Correct Answers-recycling of drugs and other substances by the
circulation of bile through the intestine and liver
, enzyme induction - Correct Answers-process by whick a drug increases the activity of the
hepatic microsomal enzymes
excretion - Correct Answers-the process of removing substances from the body
first-pass effect - Correct Answers-mechanism whereby drugs are absorbed enter into the
hepatic portal circulation and are inactivated by the liver before they reach the general
circulation
fetal-placental barrier - Correct Answers-special anatomic barrier that inhibits many chemicals
and drugs from entering the fetus
hepatic microsomal enzyme system - Correct Answers-as it relates to phamacotherapy, liver
enzymes that metabolize drugs as well as nutrients and other endogenous substances,
sometimes called the P-450 System
isozymes - Correct Answers-multiple similar forms of an enzyme that perform slightly different
metabolic functions
loading dose - Correct Answers-relatively large dose of a drug given at the beginning of
treatment to rapidly obtain a therapeutic response
maintenance doses - Correct Answers-amount of drug that keeps the plasma drug
concentration in the therapeutic range
metabolism - Correct Answers-the process used by the body to chemically change a drug
molecule, also called biotransformation
material in question-answer based format.
Guaranteed A+
Absorption - Correct Answers-the process by which drug molecules move from their site of
administration to the blood
Affinity - Correct Answers-the ability of some tissues to attract, accumulate and store drugs in
high concentrations relative to other tissues
blood-brain barrier - Correct Answers-Blood vessels (capillaries) that selectively let certain
substances enter the brain tissue and keep other substances out
diffusion - Correct Answers-process by which molecules tend to move from an area where they
are more concentrated to an area where they are less concentrated
distribution - Correct Answers-the transport of drugs throughout the body after they are
absorbed
drug-protein complexes - Correct Answers-formed when a drugh that binds reversibly to a
plasma protein, particularly albumin, that makes the drug unavailable for distribution to its site
of action
enterohepatic recirculation - Correct Answers-recycling of drugs and other substances by the
circulation of bile through the intestine and liver
, enzyme induction - Correct Answers-process by whick a drug increases the activity of the
hepatic microsomal enzymes
excretion - Correct Answers-the process of removing substances from the body
first-pass effect - Correct Answers-mechanism whereby drugs are absorbed enter into the
hepatic portal circulation and are inactivated by the liver before they reach the general
circulation
fetal-placental barrier - Correct Answers-special anatomic barrier that inhibits many chemicals
and drugs from entering the fetus
hepatic microsomal enzyme system - Correct Answers-as it relates to phamacotherapy, liver
enzymes that metabolize drugs as well as nutrients and other endogenous substances,
sometimes called the P-450 System
isozymes - Correct Answers-multiple similar forms of an enzyme that perform slightly different
metabolic functions
loading dose - Correct Answers-relatively large dose of a drug given at the beginning of
treatment to rapidly obtain a therapeutic response
maintenance doses - Correct Answers-amount of drug that keeps the plasma drug
concentration in the therapeutic range
metabolism - Correct Answers-the process used by the body to chemically change a drug
molecule, also called biotransformation
