PRITE Clinical Neurology
PRITE neurology high yield questions 2025
60 y/o right-handed M, getting lost, only writes on right half of paper. Left-sided
hemineglect.
Where is the lesion? - Correct Ans-RIGHT PARIETAL LOBE
66 y/o with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness,
nystagmus, hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left.
Dx? - Correct Ans-LATERAL MEDULLARY STROKE
78 y/o pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt
appeared to be unaware that there was a problem of weakness on one side of this body.
When asked to raise the weak arm, the patient raised his normal arm. When the failure
to raise the paralyzed arm was pointed out to pt, he admitted that the arm was slightly
weak. He also neglects the side of the body when dressing and grooming. Pt did not
shave one side of his face, had difficulty putting a shirt on when it was turned inside out.
Area of brain likely affected by stroke? - Correct Ans-RIGHT PARIETAL LOBE
26 y.o. w/HA and R-hand clumsiness for weeks. Exam shows difficulty w/rapid
alternating movements of hand, overt intention tremor on finger-to-nose, and mildly
dysmetric finger tamping. CNS intact and no papilledema. Where will damage show on
MRI? (5x) - Correct Ans-CEREBELLUM
Adult neurogenesis in which area of the brain? (x2) - Correct Ans-HIPPOCAMPUS
Rapid onset of right facial weakness, left limb weakness, diplopia: (2x) - Correct Ans-
BRAIN STEM INFARCTION
Which cell types secretes innate pro-inflammatory cytokines TNF - alpha and Il -1 B in
pts with inflammatory conditions that affect the brain? (X2) - Correct Ans-MICROGLIA
1|Page
, PRITE Clinical Neurology
DA release in what structure represents common final event assoc w reinforcing effects
of opiates, cocaine, amphetamines, nicotine, PCP, and alcohol? (4x) - Correct Ans-
NUCLEUS ACCUMBENS
Role of glycine at NMDA receptor (x2) - Correct Ans-Obligate coagonist
which NT last to mature in CNS of children and adults - Correct Ans-Cholinergic
A compound that increases muscle mass by increasing episodic secretion of GH (2x): -
Correct Ans-GAMMA hydroxylbutyrate
Visual problem in pituitary tumor compressing optic chiasm (10x) - Correct Ans-
BITEMPORAL HEMIANOPSIA
Unsteady gait, appendicular ataxia in LE only and normal eye movement. Walks with
lurching broad-based gait. (8x) - Correct Ans-CEREBELLAR DEGENERATION
(ALCOHOLIC)
Severe occipital HA, BL papilledema and no other abnormalities. Chronic acne treated
with isotretinoin. Lumbar puncture elevated opening pressure with no cells, 62 mg/dl
glucose, and 22mg/dl protein. CT is normal. (7x) - Correct Ans-PSEUDOTUMOR CEREBRI
66 y/o c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On
exam, mild impairment of vertical gaze on smooth pursuit/ saccades, mild axial rigidity &
minimal rigidity of upper extremities, along w mild slowness of movement on finger
tapping, hand opening & wrist opposition. Posture nml. Gait tentative/awkward, but w/o
shuffling, ataxia, tremor. Pt is slow in arising from a chair. Most likely dx: (7x) - Correct
Ans-Progressive Supranuclear palsy
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PRITE neurology high yield questions 2025
60 y/o right-handed M, getting lost, only writes on right half of paper. Left-sided
hemineglect.
Where is the lesion? - Correct Ans-RIGHT PARIETAL LOBE
66 y/o with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness,
nystagmus, hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left.
Dx? - Correct Ans-LATERAL MEDULLARY STROKE
78 y/o pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt
appeared to be unaware that there was a problem of weakness on one side of this body.
When asked to raise the weak arm, the patient raised his normal arm. When the failure
to raise the paralyzed arm was pointed out to pt, he admitted that the arm was slightly
weak. He also neglects the side of the body when dressing and grooming. Pt did not
shave one side of his face, had difficulty putting a shirt on when it was turned inside out.
Area of brain likely affected by stroke? - Correct Ans-RIGHT PARIETAL LOBE
26 y.o. w/HA and R-hand clumsiness for weeks. Exam shows difficulty w/rapid
alternating movements of hand, overt intention tremor on finger-to-nose, and mildly
dysmetric finger tamping. CNS intact and no papilledema. Where will damage show on
MRI? (5x) - Correct Ans-CEREBELLUM
Adult neurogenesis in which area of the brain? (x2) - Correct Ans-HIPPOCAMPUS
Rapid onset of right facial weakness, left limb weakness, diplopia: (2x) - Correct Ans-
BRAIN STEM INFARCTION
Which cell types secretes innate pro-inflammatory cytokines TNF - alpha and Il -1 B in
pts with inflammatory conditions that affect the brain? (X2) - Correct Ans-MICROGLIA
1|Page
, PRITE Clinical Neurology
DA release in what structure represents common final event assoc w reinforcing effects
of opiates, cocaine, amphetamines, nicotine, PCP, and alcohol? (4x) - Correct Ans-
NUCLEUS ACCUMBENS
Role of glycine at NMDA receptor (x2) - Correct Ans-Obligate coagonist
which NT last to mature in CNS of children and adults - Correct Ans-Cholinergic
A compound that increases muscle mass by increasing episodic secretion of GH (2x): -
Correct Ans-GAMMA hydroxylbutyrate
Visual problem in pituitary tumor compressing optic chiasm (10x) - Correct Ans-
BITEMPORAL HEMIANOPSIA
Unsteady gait, appendicular ataxia in LE only and normal eye movement. Walks with
lurching broad-based gait. (8x) - Correct Ans-CEREBELLAR DEGENERATION
(ALCOHOLIC)
Severe occipital HA, BL papilledema and no other abnormalities. Chronic acne treated
with isotretinoin. Lumbar puncture elevated opening pressure with no cells, 62 mg/dl
glucose, and 22mg/dl protein. CT is normal. (7x) - Correct Ans-PSEUDOTUMOR CEREBRI
66 y/o c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On
exam, mild impairment of vertical gaze on smooth pursuit/ saccades, mild axial rigidity &
minimal rigidity of upper extremities, along w mild slowness of movement on finger
tapping, hand opening & wrist opposition. Posture nml. Gait tentative/awkward, but w/o
shuffling, ataxia, tremor. Pt is slow in arising from a chair. Most likely dx: (7x) - Correct
Ans-Progressive Supranuclear palsy
2|Page
