CNPR REVISION EXAMS 2025/2026 QUESTIONS WITH
ANSWERS RATED A+
✔✔What DIFFERENTIATES a caplet from a tablet? - ✔✔Caplets are shaped like
capsules and have film coatings to aid in swallowing. (pg36)
✔✔Where will you find the legend "Caution: Federal Law prohibits dispensing without a
prescription"? - ✔✔on the label of all prescription drugs (pg39)
✔✔What happens in slow acetylators? - ✔✔Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain in the body longer.
✔✔About _____ of the people in the U.S. are slow acetylators. - ✔✔50%
✔✔Which of the following statements about drug-drug interactions is INCORRECT? -
✔✔Drug-drug interactions are always harmful
✔✔T/F: Smoking decreases the effectiveness of some drugs. - ✔✔True
✔✔Which of the following statements about dietary supplements is INCORRECT? -
✔✔Because dietary supplements are not drugs, interactions with drugs are not a
concern.
✔✔Which statement/s is/are INCORRECT about an ideal drug, or magic bullet as
Ehrlich phrased it? - ✔✔all are correct:
A. It does not exist.
B. It would be aimed precisely at a disease site.
C. It would not harm healthy tissues.
✔✔Which statement accurately differentiates resistance from tolerance? - ✔✔Tolerance
refers to a person's diminished response to a drug after repeated use, while resistance
applies to microorganisms' or cancel cells' abilities to withstand drug effects.
✔✔T/F: Between 3% and 7% of hospital admissions in the United States are estimated
to be for treatment of adverse drug reactions. - ✔✔true
✔✔Which statement is true about the universal scale for quantifying the severity of an
adverse drug reaction? - ✔✔None of these statements are true because there is no
such scale
A. The severities of adverse drug reactions are quantified by their chronicity.
B. The severities of adverse drug reactions are quantified by their threat to life.
✔✔Why is noncompliance a serious public health concern? - ✔✔It increases the cost of
medical care.
,✔✔Which of the following is NOT eligible for patent protection under U.S. regulations? -
✔✔Companies can be granted patents for all of these things
✔✔T/F: Drugs' trade names are often unrelated to their intended use. - ✔✔False
✔✔T/F: Like foods and household products, generic drugs are usually lower quality than
the brand name drugs for which they are marketed as equivalents. - ✔✔False
✔✔Legally, bioequivalence of different versions of a drug can vary by up to ________. -
✔✔20%
✔✔Which of the following statements about biologics is INCORRECT? - ✔✔They do not
cause immune responses.
✔✔T/F: "Large molecule" products are developed and manufactured by a chemical
process. - ✔✔False
✔✔What are drugs that attract or bind to cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - ✔✔agonists
✔✔Which term denotes how an API works in the body? - ✔✔mechanism of action
✔✔What cements the active and inert components together to maintain cohesive
portions? - ✔✔binders
✔✔What does the medical abbreviation BID denote? - ✔✔twice a day
✔✔What is the medical abbreviation for as needed? - ✔✔PRN
✔✔Which components might cause patients' different reactions to brand name and
generic drugs? - ✔✔differences in inactive ingredients
✔✔T/F: All cells have a nucleus. - ✔✔False
✔✔Which of the following does NOT affect drug response? - ✔✔All of these factors
influence drug response.
A. the patient's genetic makeup, age, body size, and use of other drugs and dietary
supplements.
B. the patient's other conditions or diseases.
C. whether or not the patient takes the drug properly
, ✔✔T/F: Drug reactions are predictable because they do not occur after a person has
been previously exposed to the drug one or more times without any allergic reactions. -
✔✔False
✔✔What is the typical relationship between a drug's site of administration and site of
action? - ✔✔They are usually somewhat removed from each other.
✔✔What is CMAX? - ✔✔the peak plasma concentration on a measuring curve
✔✔Which of the following is NOT a main concept in clinical pharmacology? -
✔✔Pharmacoprocesses
✔✔Which of the following is NOT a route of drug administration? - ✔✔transfugal
✔✔How are intradermal drugs delivered? - ✔✔by injection under the skin
✔✔What is an example of intravenous drug delivery? - ✔✔an injection of anesthetic
directly into the bloodstream
✔✔What are the major organs of the gastrointestinal system? - ✔✔the mouth,
esophagus, stomach, liver, pancreas, gallbladder, small and large intestines
✔✔Who is normally responsible for selling to distributors? - ✔✔NAMs
✔✔How often do secondary drug wholesale distributors buy their drugs directly from
manufactures? - ✔✔sometimes
✔✔T/F: By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufactures. - ✔✔False
✔✔T/F: Only 3 companies account for nearly 90% of all drug wholesale sales. - ✔✔True
✔✔What type of sale bypasses the need for intermediary distributors? -
✔✔manufacturer-direct sales
✔✔What is a group purchasing organization (GPO)? - ✔✔an entity consisting of two or
more hospitals or other health care entities that negotiates contracts on behalf of its
members
✔✔Prescriptions dispensed by mail-order pharmacies are, on average, around
____________ than those dispensed by retail pharmacies. - ✔✔3 times larger
✔✔What are examples of non-stock sales? - ✔✔-brokerage sales
ANSWERS RATED A+
✔✔What DIFFERENTIATES a caplet from a tablet? - ✔✔Caplets are shaped like
capsules and have film coatings to aid in swallowing. (pg36)
✔✔Where will you find the legend "Caution: Federal Law prohibits dispensing without a
prescription"? - ✔✔on the label of all prescription drugs (pg39)
✔✔What happens in slow acetylators? - ✔✔Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain in the body longer.
✔✔About _____ of the people in the U.S. are slow acetylators. - ✔✔50%
✔✔Which of the following statements about drug-drug interactions is INCORRECT? -
✔✔Drug-drug interactions are always harmful
✔✔T/F: Smoking decreases the effectiveness of some drugs. - ✔✔True
✔✔Which of the following statements about dietary supplements is INCORRECT? -
✔✔Because dietary supplements are not drugs, interactions with drugs are not a
concern.
✔✔Which statement/s is/are INCORRECT about an ideal drug, or magic bullet as
Ehrlich phrased it? - ✔✔all are correct:
A. It does not exist.
B. It would be aimed precisely at a disease site.
C. It would not harm healthy tissues.
✔✔Which statement accurately differentiates resistance from tolerance? - ✔✔Tolerance
refers to a person's diminished response to a drug after repeated use, while resistance
applies to microorganisms' or cancel cells' abilities to withstand drug effects.
✔✔T/F: Between 3% and 7% of hospital admissions in the United States are estimated
to be for treatment of adverse drug reactions. - ✔✔true
✔✔Which statement is true about the universal scale for quantifying the severity of an
adverse drug reaction? - ✔✔None of these statements are true because there is no
such scale
A. The severities of adverse drug reactions are quantified by their chronicity.
B. The severities of adverse drug reactions are quantified by their threat to life.
✔✔Why is noncompliance a serious public health concern? - ✔✔It increases the cost of
medical care.
,✔✔Which of the following is NOT eligible for patent protection under U.S. regulations? -
✔✔Companies can be granted patents for all of these things
✔✔T/F: Drugs' trade names are often unrelated to their intended use. - ✔✔False
✔✔T/F: Like foods and household products, generic drugs are usually lower quality than
the brand name drugs for which they are marketed as equivalents. - ✔✔False
✔✔Legally, bioequivalence of different versions of a drug can vary by up to ________. -
✔✔20%
✔✔Which of the following statements about biologics is INCORRECT? - ✔✔They do not
cause immune responses.
✔✔T/F: "Large molecule" products are developed and manufactured by a chemical
process. - ✔✔False
✔✔What are drugs that attract or bind to cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - ✔✔agonists
✔✔Which term denotes how an API works in the body? - ✔✔mechanism of action
✔✔What cements the active and inert components together to maintain cohesive
portions? - ✔✔binders
✔✔What does the medical abbreviation BID denote? - ✔✔twice a day
✔✔What is the medical abbreviation for as needed? - ✔✔PRN
✔✔Which components might cause patients' different reactions to brand name and
generic drugs? - ✔✔differences in inactive ingredients
✔✔T/F: All cells have a nucleus. - ✔✔False
✔✔Which of the following does NOT affect drug response? - ✔✔All of these factors
influence drug response.
A. the patient's genetic makeup, age, body size, and use of other drugs and dietary
supplements.
B. the patient's other conditions or diseases.
C. whether or not the patient takes the drug properly
, ✔✔T/F: Drug reactions are predictable because they do not occur after a person has
been previously exposed to the drug one or more times without any allergic reactions. -
✔✔False
✔✔What is the typical relationship between a drug's site of administration and site of
action? - ✔✔They are usually somewhat removed from each other.
✔✔What is CMAX? - ✔✔the peak plasma concentration on a measuring curve
✔✔Which of the following is NOT a main concept in clinical pharmacology? -
✔✔Pharmacoprocesses
✔✔Which of the following is NOT a route of drug administration? - ✔✔transfugal
✔✔How are intradermal drugs delivered? - ✔✔by injection under the skin
✔✔What is an example of intravenous drug delivery? - ✔✔an injection of anesthetic
directly into the bloodstream
✔✔What are the major organs of the gastrointestinal system? - ✔✔the mouth,
esophagus, stomach, liver, pancreas, gallbladder, small and large intestines
✔✔Who is normally responsible for selling to distributors? - ✔✔NAMs
✔✔How often do secondary drug wholesale distributors buy their drugs directly from
manufactures? - ✔✔sometimes
✔✔T/F: By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufactures. - ✔✔False
✔✔T/F: Only 3 companies account for nearly 90% of all drug wholesale sales. - ✔✔True
✔✔What type of sale bypasses the need for intermediary distributors? -
✔✔manufacturer-direct sales
✔✔What is a group purchasing organization (GPO)? - ✔✔an entity consisting of two or
more hospitals or other health care entities that negotiates contracts on behalf of its
members
✔✔Prescriptions dispensed by mail-order pharmacies are, on average, around
____________ than those dispensed by retail pharmacies. - ✔✔3 times larger
✔✔What are examples of non-stock sales? - ✔✔-brokerage sales
