,USMLE Step 3 – Pediatrics: Clinical Syndromes,
High-Yield Facts & Management Flashcards
2025/2026.
WAGR syndrome
wilms's tumor, aniridia, GU anomalies, mental retardation
PAX6+WT1
VACTERL abnormalities
Vertebral defects
anal atresia
cardiacabnormalities
tracheoesophageal fistula
Renal anomalies
limb syndrome
Common variable immunodeficiency
antibody deficiencies in CVID may be as profound as in XLA but with normal numbers of circulating
immunoglobulin-bearing B-lymphocytes
Henoch-Schonlein Purpura
1) petechial rash-buttocks, 2) arthritis, and 3) abdominal or renal complications
VSD
holosystolic murmur next to sternum
think about fetal alcohol syndrome, TORCH, Down syndrome
ASD
fixed, split S2 and palpitation
Endocarditis prophylaxis
PDA, VSD, ASD, tetralogy except asymptomatic, sedundum type ASD.
duodenal atresia
DOWN syndrome
MMR contraindicated
anaphylaxis to neomycin or gelatin, thrombocytopenia after first dose, recently immunoglobulin,
MMR not contraindicated
, TB, breastfeeding, asymptomatic HIV infection, anaphylaxis to eggs
11 世纪
多盐少糖性欲强血压高
17 世纪
多盐少糖性欲弱血压高
21 世纪
健康世纪：少盐少糖忙做爱（性欲强），血压低
intussusception
abdomen U/S
slipped capital femoral epiphysis
obese boys
limp and hip pain
avascular necrosis, femoral head and chondrolysis
immediate internal fixation with a single screw
DOWN syndrome
endocardial cushion defect
duodenal atresia
hirschsprung's disease
hypothyroidism
Alzheimer's
antism, ADHD
acute leukemia
Sickle cell anemia:
Glutamic acid is changed into valine at 6th position of β chain
α2β2 is abnormal called Hb S, normal called Hb A
thalassemia
α problem, α-/-- called Hb H disease (β4), --/-- hydrops fetalis, Hb Barts(γ4)
β problem, minor and major, latter no β chain, a lot of α2γ2 (Hb F)
sick cell-beta zero thalassemia and sickle cell beta plus thalassemia
two beta chains, one is sickle, the other is thalassemia.
children constipation
magnesium hydroxide
turner syndrome
High-Yield Facts & Management Flashcards
2025/2026.
WAGR syndrome
wilms's tumor, aniridia, GU anomalies, mental retardation
PAX6+WT1
VACTERL abnormalities
Vertebral defects
anal atresia
cardiacabnormalities
tracheoesophageal fistula
Renal anomalies
limb syndrome
Common variable immunodeficiency
antibody deficiencies in CVID may be as profound as in XLA but with normal numbers of circulating
immunoglobulin-bearing B-lymphocytes
Henoch-Schonlein Purpura
1) petechial rash-buttocks, 2) arthritis, and 3) abdominal or renal complications
VSD
holosystolic murmur next to sternum
think about fetal alcohol syndrome, TORCH, Down syndrome
ASD
fixed, split S2 and palpitation
Endocarditis prophylaxis
PDA, VSD, ASD, tetralogy except asymptomatic, sedundum type ASD.
duodenal atresia
DOWN syndrome
MMR contraindicated
anaphylaxis to neomycin or gelatin, thrombocytopenia after first dose, recently immunoglobulin,
MMR not contraindicated
, TB, breastfeeding, asymptomatic HIV infection, anaphylaxis to eggs
11 世纪
多盐少糖性欲强血压高
17 世纪
多盐少糖性欲弱血压高
21 世纪
健康世纪：少盐少糖忙做爱（性欲强），血压低
intussusception
abdomen U/S
slipped capital femoral epiphysis
obese boys
limp and hip pain
avascular necrosis, femoral head and chondrolysis
immediate internal fixation with a single screw
DOWN syndrome
endocardial cushion defect
duodenal atresia
hirschsprung's disease
hypothyroidism
Alzheimer's
antism, ADHD
acute leukemia
Sickle cell anemia:
Glutamic acid is changed into valine at 6th position of β chain
α2β2 is abnormal called Hb S, normal called Hb A
thalassemia
α problem, α-/-- called Hb H disease (β4), --/-- hydrops fetalis, Hb Barts(γ4)
β problem, minor and major, latter no β chain, a lot of α2γ2 (Hb F)
sick cell-beta zero thalassemia and sickle cell beta plus thalassemia
two beta chains, one is sickle, the other is thalassemia.
children constipation
magnesium hydroxide
turner syndrome
