RTBC- IV Contrast Properties UPDATED
ACTUAL Exam Questions and CORRECT
Answers
True or False
In the terms of IV contrast, iodine is usually very beneficial to the human body. - CORRECT
ANSWER - FALSE
Iodine is usually very TOXIC to the human body. While generally safe and beneficial for
medical imaging, iodine contrast must be used cautiously in patients with kidney issues or iodine
allergies.
What chemical compound is iodine typically bound to in iodinated contrast media to reduce
toxicity and enhance patient safety? - CORRECT ANSWER - Bound to benzene ring to
improve tolerability in the human body
What is the role of a benzene ring in the chemical structure of iodinated contrast media? -
CORRECT ANSWER - Serves as a stable base for binding iodine atoms. It is an organic
molecule that is not so easily rejected by the human body, makes the body tolerate the iodine.
Is water-soluble iodinated contrast media considered safe for IV injection? - CORRECT
ANSWER - Water-soluble iodinated contrast media is specially formulated for intravenous
use.
Which characteristic helps differentiate non-ionic iodinated contrast media from ionic contrast
media? - CORRECT ANSWER - Ionic agents dissociate into charged particles in solution,
contributing to higher osmolality and potentially more side effects whereas non-ionic agents do
not. Non-ionic agents do not associate into ions, resulting in lower osmolality and fewer adverse
reactions.
, If an ionic iodinated contrast agent is place into a pitcher of fluid, what will most likely occur? -
CORRECT ANSWER - The ionic contrast agent will dissociate into positively and
negatively charged ions in solution, which increases the osmolality of the fluid. This property
will/can affect the risk of adverse reactions in patients.
-One molecule breaks apart into smaller molecules that are charged
Consider the idea of an ionic contrast agent when it is placed into a solution-like blood, what
occurs? - CORRECT ANSWER - The ionic contrast agent breaks apart and forms
individual particles called ions. This is not desirable.
If an non-ionic iodinated contrast agent is place into a pitcher of fluid, what will most likely
occur? - CORRECT ANSWER - The non-ionic iodinated contrast agents do not dissociate
into charged particles when placed in solution. Remain as whole molecules, resulting in lower
osmolality and generally causing fewer adverse reactions compared to ionic.
What is the primary difference between ionic and non-ionic iodinated contrast agents? -
CORRECT ANSWER - Non-ionic agents do not dissociate into charged particles.
Which of the following contrast agents is also considered safe for IV injection, in addition to
iodinated agents?
Barium Sulfate
Air
Gadolinium-based agents
Calcium Carbonate - CORRECT ANSWER - Gadolinium-based agents
Why are non-ionic contrast agents generally preferred over ionic agents for IV administration? -
CORRECT ANSWER - They have a lower risk of adverse reactions due to lower
osmolality
ACTUAL Exam Questions and CORRECT
Answers
True or False
In the terms of IV contrast, iodine is usually very beneficial to the human body. - CORRECT
ANSWER - FALSE
Iodine is usually very TOXIC to the human body. While generally safe and beneficial for
medical imaging, iodine contrast must be used cautiously in patients with kidney issues or iodine
allergies.
What chemical compound is iodine typically bound to in iodinated contrast media to reduce
toxicity and enhance patient safety? - CORRECT ANSWER - Bound to benzene ring to
improve tolerability in the human body
What is the role of a benzene ring in the chemical structure of iodinated contrast media? -
CORRECT ANSWER - Serves as a stable base for binding iodine atoms. It is an organic
molecule that is not so easily rejected by the human body, makes the body tolerate the iodine.
Is water-soluble iodinated contrast media considered safe for IV injection? - CORRECT
ANSWER - Water-soluble iodinated contrast media is specially formulated for intravenous
use.
Which characteristic helps differentiate non-ionic iodinated contrast media from ionic contrast
media? - CORRECT ANSWER - Ionic agents dissociate into charged particles in solution,
contributing to higher osmolality and potentially more side effects whereas non-ionic agents do
not. Non-ionic agents do not associate into ions, resulting in lower osmolality and fewer adverse
reactions.
, If an ionic iodinated contrast agent is place into a pitcher of fluid, what will most likely occur? -
CORRECT ANSWER - The ionic contrast agent will dissociate into positively and
negatively charged ions in solution, which increases the osmolality of the fluid. This property
will/can affect the risk of adverse reactions in patients.
-One molecule breaks apart into smaller molecules that are charged
Consider the idea of an ionic contrast agent when it is placed into a solution-like blood, what
occurs? - CORRECT ANSWER - The ionic contrast agent breaks apart and forms
individual particles called ions. This is not desirable.
If an non-ionic iodinated contrast agent is place into a pitcher of fluid, what will most likely
occur? - CORRECT ANSWER - The non-ionic iodinated contrast agents do not dissociate
into charged particles when placed in solution. Remain as whole molecules, resulting in lower
osmolality and generally causing fewer adverse reactions compared to ionic.
What is the primary difference between ionic and non-ionic iodinated contrast agents? -
CORRECT ANSWER - Non-ionic agents do not dissociate into charged particles.
Which of the following contrast agents is also considered safe for IV injection, in addition to
iodinated agents?
Barium Sulfate
Air
Gadolinium-based agents
Calcium Carbonate - CORRECT ANSWER - Gadolinium-based agents
Why are non-ionic contrast agents generally preferred over ionic agents for IV administration? -
CORRECT ANSWER - They have a lower risk of adverse reactions due to lower
osmolality
