GNRS 5669 UTMB FNP 1 Anemia Questions With
Complete Solutions
A - direct and + indirect Coombs means? Correct
Answers -prior transfusion or pregnancy
-not AIHA*
alloantibody
A + direct or indirect Coombs means? Correct
Answers AIHA
Alpha Thal. intermedia dx?
Tx?
*not on test per prof 5/24 Correct Answers
anemia
-reticulocytosis
-splenomegaly
-Hgb H
-routine transfusions not needed
Alpha Thal. major, what happens? Correct Answers
die in utero or birth
-hydrops fetalis
-HgF: none
Alpha Thal. trait. dx?
Genetics? Correct Answers -asymptomatic
-MCV: < 80
-hypochromic
-Hgb A, A2, F: nml
,-reti count: nml
-CBC of parent shows similar microcytosis*
Anemia of chronic dz dx? Correct Answers 1/3
mild microcytosis
2/3 normocyte
MCV 80-100
--Fe: decr.
--TIBC: decr.
--Ferritin: nml/incr.
--reti count: nml/low
Aplastic anemia Correct Answers -hypocellular
bone marrow
< 25% cell
-peripheral blood pancytopenia
H/H: decr
reti count: < .5
Autoimmune hemolytic anemia
(AIHA) define? Correct Answers -autoantibody
against own RBC surface antigen
-RBC destroyed in spleen by macrophages
Autoimmune hemolytic anemia:
Dx?
Tx? Correct Answers - + direct Coombs test
-Prednisone + folic acid
, B12 deficiency cause? Correct Answers pernicious
anemia
-deficiency of intrinsic factor
-autoimmune dz
Beta Thal trait microcytosis dx?
Tx? Correct Answers asymptomatic
-reti count: mild incr.
-HbA2: incr.*
-none, explain genetics of dz to pt
Beta Thal. major dx?
Tx? Correct Answers symptomatic at 6mo.
-HbF: incr.*
-HbA2: incr.
-HbA: none
-reg. maintenance blood transfusions + Fe
chelators to avoid Fe overload
(2ndy hemochromatosis)
Chronic inflammation?
Tx? Correct Answers -ferritin: nml/incr
-TIBC: decr
-MCV: nml
-reti: decr
Tx: erythropoietin
Cytopenia? Correct Answers -low blood cell count
-low RBC: anemia
-Low WBC: leukopenia/neutropenia
Complete Solutions
A - direct and + indirect Coombs means? Correct
Answers -prior transfusion or pregnancy
-not AIHA*
alloantibody
A + direct or indirect Coombs means? Correct
Answers AIHA
Alpha Thal. intermedia dx?
Tx?
*not on test per prof 5/24 Correct Answers
anemia
-reticulocytosis
-splenomegaly
-Hgb H
-routine transfusions not needed
Alpha Thal. major, what happens? Correct Answers
die in utero or birth
-hydrops fetalis
-HgF: none
Alpha Thal. trait. dx?
Genetics? Correct Answers -asymptomatic
-MCV: < 80
-hypochromic
-Hgb A, A2, F: nml
,-reti count: nml
-CBC of parent shows similar microcytosis*
Anemia of chronic dz dx? Correct Answers 1/3
mild microcytosis
2/3 normocyte
MCV 80-100
--Fe: decr.
--TIBC: decr.
--Ferritin: nml/incr.
--reti count: nml/low
Aplastic anemia Correct Answers -hypocellular
bone marrow
< 25% cell
-peripheral blood pancytopenia
H/H: decr
reti count: < .5
Autoimmune hemolytic anemia
(AIHA) define? Correct Answers -autoantibody
against own RBC surface antigen
-RBC destroyed in spleen by macrophages
Autoimmune hemolytic anemia:
Dx?
Tx? Correct Answers - + direct Coombs test
-Prednisone + folic acid
, B12 deficiency cause? Correct Answers pernicious
anemia
-deficiency of intrinsic factor
-autoimmune dz
Beta Thal trait microcytosis dx?
Tx? Correct Answers asymptomatic
-reti count: mild incr.
-HbA2: incr.*
-none, explain genetics of dz to pt
Beta Thal. major dx?
Tx? Correct Answers symptomatic at 6mo.
-HbF: incr.*
-HbA2: incr.
-HbA: none
-reg. maintenance blood transfusions + Fe
chelators to avoid Fe overload
(2ndy hemochromatosis)
Chronic inflammation?
Tx? Correct Answers -ferritin: nml/incr
-TIBC: decr
-MCV: nml
-reti: decr
Tx: erythropoietin
Cytopenia? Correct Answers -low blood cell count
-low RBC: anemia
-Low WBC: leukopenia/neutropenia
