Prostate Cancer Treatment questions
with answers
What are some symptoms of locally invasive prostate cancer? ✅✅Urinary hesitancy
Dribbling
Impotence
What are some symptoms of advanced or metastatic prostate cancer? ✅✅Back pain
Cord compression
Pathologic fractures
What is m0CRPC? ✅✅Non-metastatic Castration-Resistant Prostate Cancer
What is m1CSPC? ✅✅Metastatic Castrate-Sensitive Prostate Cancer
What is m1CRPC? ✅✅Metastatic Castration-Resistant Prostate Cancer
Castration-sensitive prostate cancer is one that has not been treated with ______ yet
OR remains responsive to treatment. ✅✅ADT, or androgen deprivation therapy
Castration-resistant prostate cancer is a disease progression despite ADT and a
castration level of testosterone, identified as <____ ng/dl ✅✅less than 50ng/dl
How is prostate cancer considered "recurrence" or "relapsed"?
(What lab value points to the cancer re-emerging) ✅✅Elevating PSA after treatment
with surgery or radiation
What are the main treatment options of localized disease? ✅✅Active surveillance or
observation
Radical Prostatectomy
Radiation Therapy
What labs are monitored during active surveillance / observation? ✅✅PSA
DRE
(Also just general Symptoms)
What is the key difference between active surveillance and observation? ✅✅Active
surveillance is for curative intent, observation is for palliative intent
Radical Prostatectomy, or RP, is considered a major inpatient surgery, with a bleeding
risk during and after surgery (T/F) ✅✅TRUE!
, What are some disadvantages of radical prostatectomy? ✅✅Incontinence
ED
Bowel complications
Radiation therapy, via External Beam Radiation Therapy (EBRT) or Brachytherapy has
EQUAL efficacy to a prostatectomy (T/F) ✅✅TRUE
Radiation Therapy eliminates the need for a major surgery (like a prostatectomy) (T/F)
✅✅TRUE
Is radiation therapy considered an inpatient or outpatient procedure? ✅✅Outpatient
What are some of the disadvantages of radiation therapy? ✅✅Bowel complications
Incontinence
ED
What is the castrate level of testosterone <____ ng/dl ✅✅less than 50ng/dl
How do you chemically castrate patients to achieve ADT (what class of medications
would you use)? ✅✅Luteinizing hormone-releasing agonists OR antagonists
What is an orchiectomy? ✅✅removal of the testicals, used for androgen deprivation
therapy (ADT)
What are the LHRH AGONISTS? ✅✅Goserelin
Leuprolide
Triptorelin
What are the LONG-TERM side effects of LHRH agonists (Goserelin, Leuprolide, and
Triptorelin)? ✅✅Osteoporosis and fracture
Obesity
Increased DM risk
Cardio events
What are some common side effects of LHRH agonists (Goserelin, Leuprolide, and
Triptorelin) ✅✅Tumor flare
Hot flashes
Gynecomastia
ED
Injection site reaction
What are the LHRH ANTAGONISTS? ✅✅Degarelix
Relugolix
with answers
What are some symptoms of locally invasive prostate cancer? ✅✅Urinary hesitancy
Dribbling
Impotence
What are some symptoms of advanced or metastatic prostate cancer? ✅✅Back pain
Cord compression
Pathologic fractures
What is m0CRPC? ✅✅Non-metastatic Castration-Resistant Prostate Cancer
What is m1CSPC? ✅✅Metastatic Castrate-Sensitive Prostate Cancer
What is m1CRPC? ✅✅Metastatic Castration-Resistant Prostate Cancer
Castration-sensitive prostate cancer is one that has not been treated with ______ yet
OR remains responsive to treatment. ✅✅ADT, or androgen deprivation therapy
Castration-resistant prostate cancer is a disease progression despite ADT and a
castration level of testosterone, identified as <____ ng/dl ✅✅less than 50ng/dl
How is prostate cancer considered "recurrence" or "relapsed"?
(What lab value points to the cancer re-emerging) ✅✅Elevating PSA after treatment
with surgery or radiation
What are the main treatment options of localized disease? ✅✅Active surveillance or
observation
Radical Prostatectomy
Radiation Therapy
What labs are monitored during active surveillance / observation? ✅✅PSA
DRE
(Also just general Symptoms)
What is the key difference between active surveillance and observation? ✅✅Active
surveillance is for curative intent, observation is for palliative intent
Radical Prostatectomy, or RP, is considered a major inpatient surgery, with a bleeding
risk during and after surgery (T/F) ✅✅TRUE!
, What are some disadvantages of radical prostatectomy? ✅✅Incontinence
ED
Bowel complications
Radiation therapy, via External Beam Radiation Therapy (EBRT) or Brachytherapy has
EQUAL efficacy to a prostatectomy (T/F) ✅✅TRUE
Radiation Therapy eliminates the need for a major surgery (like a prostatectomy) (T/F)
✅✅TRUE
Is radiation therapy considered an inpatient or outpatient procedure? ✅✅Outpatient
What are some of the disadvantages of radiation therapy? ✅✅Bowel complications
Incontinence
ED
What is the castrate level of testosterone <____ ng/dl ✅✅less than 50ng/dl
How do you chemically castrate patients to achieve ADT (what class of medications
would you use)? ✅✅Luteinizing hormone-releasing agonists OR antagonists
What is an orchiectomy? ✅✅removal of the testicals, used for androgen deprivation
therapy (ADT)
What are the LHRH AGONISTS? ✅✅Goserelin
Leuprolide
Triptorelin
What are the LONG-TERM side effects of LHRH agonists (Goserelin, Leuprolide, and
Triptorelin)? ✅✅Osteoporosis and fracture
Obesity
Increased DM risk
Cardio events
What are some common side effects of LHRH agonists (Goserelin, Leuprolide, and
Triptorelin) ✅✅Tumor flare
Hot flashes
Gynecomastia
ED
Injection site reaction
What are the LHRH ANTAGONISTS? ✅✅Degarelix
Relugolix
