HESI PHARMACOLOGY V1: EXAM
PHARM V1, 2025/2026 WITH
CORRECT/ACCURATE ANSWERS
A nurse is reviewing the record of a client who has been
prescribed baclofen (Lioresal). Which of the following disorders, if
noted in the client's history, would alert the nurse to contact the
health care provider?
1. Seizure disorders
2. Hyperthyroidism
3. Diabetes mellitus
4. Coronary artery disease - CORRECT ANSWERS- 1. Seizure
disorders
Rationale:Clients with seizure disorders may have a lowered
seizure threshold when baclofen is administered. Concurrent
therapy may require an increase in the anticonvulsive medication.
The disorders in options 2, 3, and 4 are not a concern when the
client is taking baclofen.
Cyclobenzaprine (Flexeril) is prescribed for a client to treat
muscle spasms, and the nurse is reviewing the client's record.
Which of the following disorders, if noted in the client's record,
would indicate a need to contact the health care provider
regarding the administration of this medication?
,1. Glaucoma
2. Emphysema
3. Hyperthyroidism
4. Diabetes mellitus - CORRECT ANSWERS- 1. Glaucoma
Rationale:Because this medication has anticholinergic effects, it
should be used with caution in clients with a history of urinary
retention, angle-closure glaucoma, and increased intraocular
pressure. Cyclobenzaprine hydrochloride should be used only for
short-term 2- to 3-week therapy.
In monitoring a client's response to disease-modifying
antirheumatic drugs (DMARDs), which findings would the nurse
interpret as acceptable responses? Select all that apply
.1. Symptom control during periods of emotional stress
2. Normal white blood cell counts, platelet, and neutrophil counts
3. Radiological findings that show nonprogression of joint
degeneration
4. An increased range of motion in the affected joints 3 months
into therapy
5. Inflammation and irritation at the injection site 3 days after
injection is given
6. A low-grade temperature upon rising in the morning that
remains throughout the day - CORRECT ANSWERS- 1. Symptom
control during periods of emotional stress
2. Normal white blood cell counts, platelet, and neutrophil counts
,3. Radiological findings that show nonprogression of joint
degeneration
4. An increased range of motion in the affected joints 3 months
into therapy
Rationale:Because emotional stress frequently exacerbates the
symptoms of rheumatoid arthritis, the absence of symptoms is a
positive finding. DMARDs are given to slow progression of joint
degeneration. In addition, the improvement in the range of
motion after 3 months of therapy with normal blood work is a
positive finding. Temperature elevation and inflammation and
irritation at the medication injection site could indicate signs of
infection.
The client who is human immunodeficiency virus seropositive has
been taking stavudine (d4t, Zerit). The nurse monitors which of
the following most closely while the client is taking this
medication?
1. Gait
2. Appetite
3. Level of consciousness
4. Hemoglobin and hematocrit blood levels - CORRECT ANSWERS-
1. Gait
Rationale:Stavudine (d4t, Zerit) is an antiretroviral used to
manage human immunodeficiency virus infection in clients who
do not respond to or who cannot tolerate conventional therapy.
, The medication can cause peripheral neuropathy, and the nurse
should monitor the client's gait closely and ask the client about
paresthesia. Options 2, 3, and 4 are unrelated to the use of the
medication.
The client with acquired immunodeficiency syndrome has begun
therapy with zidovudine (Retrovir, Azidothymidine, AZT, ZDV).
The nurse carefully monitors which of the following laboratory
results during treatment with this medication?
1. Blood culture
2. Blood glucose level
3. Blood urea nitrogen
4. Complete blood count - CORRECT ANSWERS- 4. Complete
blood count
Rationale:A common side effect of therapy with zidovudine is
leukopenia and anemia. The nurse monitors the complete blood
count results for these changes. Options 1, 2, and 3 are unrelated
to the use of this medication.
he nurse is reviewing the results of serum laboratory studies
drawn on a client with acquired immunodeficiency syndrome who
is receiving didanosine (Videx). The nurse interprets that the
client may have the medication discontinued by the health care
provider if which of the following significantly elevated results is
noted?
1. Serum protein
2. Blood glucose
PHARM V1, 2025/2026 WITH
CORRECT/ACCURATE ANSWERS
A nurse is reviewing the record of a client who has been
prescribed baclofen (Lioresal). Which of the following disorders, if
noted in the client's history, would alert the nurse to contact the
health care provider?
1. Seizure disorders
2. Hyperthyroidism
3. Diabetes mellitus
4. Coronary artery disease - CORRECT ANSWERS- 1. Seizure
disorders
Rationale:Clients with seizure disorders may have a lowered
seizure threshold when baclofen is administered. Concurrent
therapy may require an increase in the anticonvulsive medication.
The disorders in options 2, 3, and 4 are not a concern when the
client is taking baclofen.
Cyclobenzaprine (Flexeril) is prescribed for a client to treat
muscle spasms, and the nurse is reviewing the client's record.
Which of the following disorders, if noted in the client's record,
would indicate a need to contact the health care provider
regarding the administration of this medication?
,1. Glaucoma
2. Emphysema
3. Hyperthyroidism
4. Diabetes mellitus - CORRECT ANSWERS- 1. Glaucoma
Rationale:Because this medication has anticholinergic effects, it
should be used with caution in clients with a history of urinary
retention, angle-closure glaucoma, and increased intraocular
pressure. Cyclobenzaprine hydrochloride should be used only for
short-term 2- to 3-week therapy.
In monitoring a client's response to disease-modifying
antirheumatic drugs (DMARDs), which findings would the nurse
interpret as acceptable responses? Select all that apply
.1. Symptom control during periods of emotional stress
2. Normal white blood cell counts, platelet, and neutrophil counts
3. Radiological findings that show nonprogression of joint
degeneration
4. An increased range of motion in the affected joints 3 months
into therapy
5. Inflammation and irritation at the injection site 3 days after
injection is given
6. A low-grade temperature upon rising in the morning that
remains throughout the day - CORRECT ANSWERS- 1. Symptom
control during periods of emotional stress
2. Normal white blood cell counts, platelet, and neutrophil counts
,3. Radiological findings that show nonprogression of joint
degeneration
4. An increased range of motion in the affected joints 3 months
into therapy
Rationale:Because emotional stress frequently exacerbates the
symptoms of rheumatoid arthritis, the absence of symptoms is a
positive finding. DMARDs are given to slow progression of joint
degeneration. In addition, the improvement in the range of
motion after 3 months of therapy with normal blood work is a
positive finding. Temperature elevation and inflammation and
irritation at the medication injection site could indicate signs of
infection.
The client who is human immunodeficiency virus seropositive has
been taking stavudine (d4t, Zerit). The nurse monitors which of
the following most closely while the client is taking this
medication?
1. Gait
2. Appetite
3. Level of consciousness
4. Hemoglobin and hematocrit blood levels - CORRECT ANSWERS-
1. Gait
Rationale:Stavudine (d4t, Zerit) is an antiretroviral used to
manage human immunodeficiency virus infection in clients who
do not respond to or who cannot tolerate conventional therapy.
, The medication can cause peripheral neuropathy, and the nurse
should monitor the client's gait closely and ask the client about
paresthesia. Options 2, 3, and 4 are unrelated to the use of the
medication.
The client with acquired immunodeficiency syndrome has begun
therapy with zidovudine (Retrovir, Azidothymidine, AZT, ZDV).
The nurse carefully monitors which of the following laboratory
results during treatment with this medication?
1. Blood culture
2. Blood glucose level
3. Blood urea nitrogen
4. Complete blood count - CORRECT ANSWERS- 4. Complete
blood count
Rationale:A common side effect of therapy with zidovudine is
leukopenia and anemia. The nurse monitors the complete blood
count results for these changes. Options 1, 2, and 3 are unrelated
to the use of this medication.
he nurse is reviewing the results of serum laboratory studies
drawn on a client with acquired immunodeficiency syndrome who
is receiving didanosine (Videx). The nurse interprets that the
client may have the medication discontinued by the health care
provider if which of the following significantly elevated results is
noted?
1. Serum protein
2. Blood glucose
