Advanced Pathophysiology FINAL
EXAM STUDY GUIDE
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NR 507 Final exam study guide
NR-507 Study Guide Q’s & A’s
1. Types of immunity ch 7 & 8
a. Innate- natural epithelial barrier and inflammation the make innate
resistance and protection pg. 191 Innate immunity includes two lines of
defense: Natural barriers and inflammation.
i. Natural barriers- physical, mechanical, and biochemical barriers at the
body’s surfaces
ii. Inflamation- associated with infection usually initiates an adaptive
process that results in a long-term and very effective immunity to the
infecting microorganism, referred to a adaptive, acquired or specific
immunity. Use of the Epithelial cells with no memory function
involved.
b. Adaptive/ acquired- immune response or immunity, after innate and
inflammation, Third line of defense, initiated when innate immune system
signals the cells of adaptive immunity. There is a delay between primary
exposure to antigen and maximum response, however there is immediate action
against secondary exposure. Response is specific toward antigen. Involves T
lymphocytes, B Lymphocytes, macrophages, and dentric cells. Specific
immunologic memory by T and B lymphocytes
i. Active (Acquired) -after natural exposure to an antigen or after
immunization pg. 227
ii. Passive (Acquired)- preformed antibodies or t lymphocytes are
transferred rom a donor to the recipient, maternal to fetus, or
bone marrow transplant pg. 227
Questions
➢ What type of immunity is produced when an immunoglobulin crosses the placenta?
▪ Passive-aquired immunity
➢ The mucosal secretions of the cervix secrete which immunoglobulin?
▪ IgA
➢ A student nurse asks the clinician which cells are most primary in a
patient's immunity. What is the clinician's best answer?
• Lymphocytes.
➢ A nurse recalls humoral immunity is generated through the process of:
• producing antibodies.
➢ While taking a health history, if a person has resistance to a disease from
natural exposure to an antigen, how would the nurse document this form of
immunity?
• Active acquired
➢ What type of immunity will the nurse expect in an individual who is given
a vaccine?
• Active acquired immunity
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NR 507 Final exam study guide
➢ A new mother asks the nurse about immunity of her newborn as she is
breastfeeding. The nurse's response should include a discussion on which type
of immunity?
• Passive
➢ The nurse has been explaining to a student nurse about the different types
of immunity. Which response indicates that the student nurse has a good
understanding of adaptive immunity?
• Both the humoral and cell-mediated immunity develop memory
cells
➢ Cancer cells and virus-infected body cells can be killed before activation
of adaptive immunity by
• natural killer cells
➢ The primary immune response .
•
has a lag period while B cells proliferate and differentiate
into plasma cells
➢ Which of the following is true about the number of binding sites per functional
antibody unit?
• IgM contains 10 binding sites.
➢ Which cell of the immune system is absolutely required for an adaptive
immune response?
• Helper T cell
➢ The adaptive immune system involves three major cell types: antigen-presenting
cells, T cells, which constitute cell- mediated immunity, and B cells, which
govern humoral immunity.
➢ The nurse understands that the function of IgG is as what?
• A bond with target cells and a promoter of phagocytosis
➢ The nurse understands that which type of immunity is the longest acting?
• Natural active
➢ Natural killer cells are specialized lymphocytes that are one of the major parts
of which immunity?
• Innate
2. Alveolar ventilation/perfusion- pg. 1239 Ch 34 Effective gas exchange depends on an
approximately even distribution of gas (ventilation) and blood (perfusion) in all portion
s of the lungs. The lungs are suspended from the hila in the thoracic cavity. When the
individual is in an upright position, gravity pulls the lungs down toward the diaphragm
and compresses their lower portions or bases.
a. Ratio between the amount of air getting into the alveoli and the amount of blood
being sent to the lungs.
Questions
➢ A consequence of alveolar hypoxia is:
Pulmonary artery vasoconstriction
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NR 507 Final exam study guide
➢ The pressure required to inflate an alveolus is inversely related to:
Alveolus radius
➢ The nurse is describing the movement of blood into and out of the
capillary beds of the lungs to the body organs and tissues. What
term should the nurse use to describe this process?
Perfusion
➢ A pulmonologist is discussing the base of the lungs with staff.
Which information should be included? At the base of the lungs:
Arterial perfusion pressure exceeds alveolar gas pressure
When the pulmonologist discusses the condition in which a series of alveoli in
the left lower lo
➢ be receive adequate ventilation but do not have adequate perfusion, which
statement indicates the nurse understands this condition? When this occurs in
a patient it is called:
Alveolar dead space
➢ Which of the following conditions should the nurse monitor for in a patient
with hypoventilation?
hypercapnia
➢ A nurse is describing the pathophysiology of emphysema. Which information
should the nurse include? Emphysema results in:
the destruction of alveolar septa and air trapping
3. Dermatologic conditions and terminology ch. 46 pg. 1620,
a. macules- freckles, flat moles, change in color, less than1 cm,
b. nevi- moles pg. 1641,
c. pityriasis rosea- benign self-limiting inflammatory disorder that occurs in
young adults, with seasonal peaks spring and fall. Harmful in pregnancy.
Associated with a virus, starts with a herald patch, circular. Salmon pink, and
demarcated, usually on the trunk, acyclovir and erythromycin, and
corticosteroid creams for itching. Should go away within a few months.
d. Papule - An elevated, firm, circumscribed area less than 1 cm in diameter, Wart
(verruca), elevated moles, lichen planus, fibroma, insect bite
e. Patch - A flat, nonpalpable, irregular-shaped macule more than 1 cm in diameter,
Vitiligo, port-wine stains, mongolian spots, café-au-lait spots
f. Plaque- Elevated, firm, and rough lesion with flat top surface greater than 1 cm
in diameter, Psoriasis, seborrheic and actinic keratosis
g. Wheal - Elevated, irregular-shaped area of cutaneous edema; solid, transient;
variable diameter, Insect bites, urticaria, allergic reaction
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EXAM STUDY GUIDE
written by
GradePotential
The Marketplace to Buy and Sell your Study Material
At Stuvia, you will find the best notes, summaries, flashcards & other study material. Search for your
school or uni and find the study material you need.
www.stuvia.com
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NR 507 Final exam study guide
NR-507 Study Guide Q’s & A’s
1. Types of immunity ch 7 & 8
a. Innate- natural epithelial barrier and inflammation the make innate
resistance and protection pg. 191 Innate immunity includes two lines of
defense: Natural barriers and inflammation.
i. Natural barriers- physical, mechanical, and biochemical barriers at the
body’s surfaces
ii. Inflamation- associated with infection usually initiates an adaptive
process that results in a long-term and very effective immunity to the
infecting microorganism, referred to a adaptive, acquired or specific
immunity. Use of the Epithelial cells with no memory function
involved.
b. Adaptive/ acquired- immune response or immunity, after innate and
inflammation, Third line of defense, initiated when innate immune system
signals the cells of adaptive immunity. There is a delay between primary
exposure to antigen and maximum response, however there is immediate action
against secondary exposure. Response is specific toward antigen. Involves T
lymphocytes, B Lymphocytes, macrophages, and dentric cells. Specific
immunologic memory by T and B lymphocytes
i. Active (Acquired) -after natural exposure to an antigen or after
immunization pg. 227
ii. Passive (Acquired)- preformed antibodies or t lymphocytes are
transferred rom a donor to the recipient, maternal to fetus, or
bone marrow transplant pg. 227
Questions
➢ What type of immunity is produced when an immunoglobulin crosses the placenta?
▪ Passive-aquired immunity
➢ The mucosal secretions of the cervix secrete which immunoglobulin?
▪ IgA
➢ A student nurse asks the clinician which cells are most primary in a
patient's immunity. What is the clinician's best answer?
• Lymphocytes.
➢ A nurse recalls humoral immunity is generated through the process of:
• producing antibodies.
➢ While taking a health history, if a person has resistance to a disease from
natural exposure to an antigen, how would the nurse document this form of
immunity?
• Active acquired
➢ What type of immunity will the nurse expect in an individual who is given
a vaccine?
• Active acquired immunity
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NR 507 Final exam study guide
➢ A new mother asks the nurse about immunity of her newborn as she is
breastfeeding. The nurse's response should include a discussion on which type
of immunity?
• Passive
➢ The nurse has been explaining to a student nurse about the different types
of immunity. Which response indicates that the student nurse has a good
understanding of adaptive immunity?
• Both the humoral and cell-mediated immunity develop memory
cells
➢ Cancer cells and virus-infected body cells can be killed before activation
of adaptive immunity by
• natural killer cells
➢ The primary immune response .
•
has a lag period while B cells proliferate and differentiate
into plasma cells
➢ Which of the following is true about the number of binding sites per functional
antibody unit?
• IgM contains 10 binding sites.
➢ Which cell of the immune system is absolutely required for an adaptive
immune response?
• Helper T cell
➢ The adaptive immune system involves three major cell types: antigen-presenting
cells, T cells, which constitute cell- mediated immunity, and B cells, which
govern humoral immunity.
➢ The nurse understands that the function of IgG is as what?
• A bond with target cells and a promoter of phagocytosis
➢ The nurse understands that which type of immunity is the longest acting?
• Natural active
➢ Natural killer cells are specialized lymphocytes that are one of the major parts
of which immunity?
• Innate
2. Alveolar ventilation/perfusion- pg. 1239 Ch 34 Effective gas exchange depends on an
approximately even distribution of gas (ventilation) and blood (perfusion) in all portion
s of the lungs. The lungs are suspended from the hila in the thoracic cavity. When the
individual is in an upright position, gravity pulls the lungs down toward the diaphragm
and compresses their lower portions or bases.
a. Ratio between the amount of air getting into the alveoli and the amount of blood
being sent to the lungs.
Questions
➢ A consequence of alveolar hypoxia is:
Pulmonary artery vasoconstriction
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NR 507 Final exam study guide
➢ The pressure required to inflate an alveolus is inversely related to:
Alveolus radius
➢ The nurse is describing the movement of blood into and out of the
capillary beds of the lungs to the body organs and tissues. What
term should the nurse use to describe this process?
Perfusion
➢ A pulmonologist is discussing the base of the lungs with staff.
Which information should be included? At the base of the lungs:
Arterial perfusion pressure exceeds alveolar gas pressure
When the pulmonologist discusses the condition in which a series of alveoli in
the left lower lo
➢ be receive adequate ventilation but do not have adequate perfusion, which
statement indicates the nurse understands this condition? When this occurs in
a patient it is called:
Alveolar dead space
➢ Which of the following conditions should the nurse monitor for in a patient
with hypoventilation?
hypercapnia
➢ A nurse is describing the pathophysiology of emphysema. Which information
should the nurse include? Emphysema results in:
the destruction of alveolar septa and air trapping
3. Dermatologic conditions and terminology ch. 46 pg. 1620,
a. macules- freckles, flat moles, change in color, less than1 cm,
b. nevi- moles pg. 1641,
c. pityriasis rosea- benign self-limiting inflammatory disorder that occurs in
young adults, with seasonal peaks spring and fall. Harmful in pregnancy.
Associated with a virus, starts with a herald patch, circular. Salmon pink, and
demarcated, usually on the trunk, acyclovir and erythromycin, and
corticosteroid creams for itching. Should go away within a few months.
d. Papule - An elevated, firm, circumscribed area less than 1 cm in diameter, Wart
(verruca), elevated moles, lichen planus, fibroma, insect bite
e. Patch - A flat, nonpalpable, irregular-shaped macule more than 1 cm in diameter,
Vitiligo, port-wine stains, mongolian spots, café-au-lait spots
f. Plaque- Elevated, firm, and rough lesion with flat top surface greater than 1 cm
in diameter, Psoriasis, seborrheic and actinic keratosis
g. Wheal - Elevated, irregular-shaped area of cutaneous edema; solid, transient;
variable diameter, Insect bites, urticaria, allergic reaction
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